Sexual dimorphism in cardiac remodeling: the molecular mechanisms ruled by sex hormones in the heart
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A. Leite-Moreira | F. Amado | R. Ferreira | Fábio Trindade | J. Neves | Rita Nogueira-Ferreira | Mário Santos | Cláudia Ferreira | Francisco Amado
[1] Brian A. Aguado,et al. Matters of the heart: Cellular sex differences. , 2021, Journal of molecular and cellular cardiology.
[2] Xiumeng Hua,et al. Single-Cell Transcriptomic Atlas of Different Human Cardiac Arteries Identifies Cell Types Associated With Vascular Physiology , 2021, Arteriosclerosis, thrombosis, and vascular biology.
[3] R. Mostany,et al. Alterations in the estrogen receptor profile of cardiovascular tissues during aging , 2021, GeroScience.
[4] D. Kass,et al. Cellular and molecular pathobiology of heart failure with preserved ejection fraction , 2021, Nature Reviews Cardiology.
[5] Catherine L. Worth,et al. Cells of the adult human heart , 2020, Nature.
[6] C. Shim. Heart Failure with Preserved Ejection Fraction: the Major Unmet Need in Cardiology , 2020, Korean circulation journal.
[7] M. Eghbali,et al. The Role of Estrogen Receptors in Cardiovascular Disease , 2020, International journal of molecular sciences.
[8] M. Estrada,et al. Androgen-Regulated Cardiac Metabolism in Aging Men , 2020, Frontiers in Endocrinology.
[9] V. Regitz-Zagrosek. Sex and Gender Differences in Heart Failure , 2020, International journal of heart failure.
[10] S. Anker,et al. Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future , 2020, Clinical Research in Cardiology.
[11] Wenwei Bai,et al. Testosterone Supplementation in Patients With Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials , 2020, Frontiers in Endocrinology.
[12] F. Brozovich,et al. The vasculature in HFpEF vs HFrEF: differences in contractile protein expression produce distinct phenotypes , 2019, Heliyon.
[13] D. Kitzman,et al. Heart failure with preserved ejection fraction: New approaches to diagnosis and management , 2019, Clinical cardiology.
[14] Sanjiv J. Shah,et al. Effects of Sacubitril-Valsartan Versus Valsartan in Women Compared With Men With Heart Failure and Preserved Ejection Fraction , 2019, Circulation.
[15] H. D. den Ruijter,et al. Estrogen Contributions to Microvascular Dysfunction Evolving to Heart Failure With Preserved Ejection Fraction , 2019, Front. Endocrinol..
[16] Yangxin Li,et al. The Influence of Sex on Cardiac Physiology and Cardiovascular Diseases , 2019, Journal of Cardiovascular Translational Research.
[17] E. Dworatzek,et al. The Role of 17β-Estradiol and Estrogen Receptors in Regulation of Ca2+ Channels and Mitochondrial Function in Cardiomyocytes , 2019, Front. Endocrinol..
[18] R. Wachter,et al. Heterogeneous Metabolic Response to Exercise Training in Heart Failure with Preserved Ejection Fraction , 2019, Journal of clinical medicine.
[19] A. Abreu,et al. Exercise training in women with cardiovascular disease: Differential response and barriers - review and perspective. , 2019, European journal of preventive cardiology.
[20] J. Lindenfeld,et al. Sex Differences in Outcomes and Responses to Spironolactone in Heart Failure With Preserved Ejection Fraction: A Secondary Analysis of TOPCAT Trial. , 2019, JACC. Heart failure.
[21] V. Regitz-Zagrosek,et al. Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload , 2019, Biology of Sex Differences.
[22] R. Mostany,et al. Estrogen receptor profiles across tissues from male and female Rattus norvegicus , 2019, Biology of Sex Differences.
[23] G. Su,et al. G Protein-Coupled Estrogen Receptor 1 Inhibits Angiotensin II-Induced Cardiomyocyte Hypertrophy via the Regulation of PI3K-Akt-mTOR Signalling and Autophagy , 2019, International journal of biological sciences.
[24] N. Stachenfeld,et al. Sex differences in endothelial function important to vascular health and overall cardiovascular disease risk across the lifespan. , 2018, American journal of physiology. Heart and circulatory physiology.
[25] Mohammad T Elnakish,et al. Protein Kinase A as a Promising Target for Heart Failure Drug Development. , 2018, Archives of medical research.
[26] Shiqiang Yu,et al. GPR30 Attenuates Myocardial Fibrosis in Diabetic Ovariectomized Female Rats: Role of iNOS Signaling. , 2018, DNA and cell biology.
[27] V. Regitz-Zagrosek,et al. Sex-specific regulation of collagen I and III expression by 17&bgr;-Estradiol in cardiac fibroblasts: role of estrogen receptors , 2018, Cardiovascular research.
[28] T. Marwick,et al. Sex Differences in Cardiovascular Pathophysiology: Why Women Are Overrepresented in Heart Failure With Preserved Ejection Fraction , 2018, Circulation.
[29] J. Tardif,et al. Sex, drugs, and heart failure: a sex‐sensitive review of the evidence base behind current heart failure clinical guidelines , 2018, ESC heart failure.
[30] H. Van Remmen,et al. G protein‐coupled estrogen receptor (GPER) deficiency induces cardiac remodeling through oxidative stress , 2018, Translational research : the journal of laboratory and clinical medicine.
[31] L. Lei,et al. Hormone treatments in congestive heart failure , 2018, The Journal of international medical research.
[32] M. Eghbali,et al. The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy , 2017, Biology of Sex Differences.
[33] I. Lambrinoudaki,et al. Androgens and cardiovascular disease in women and men. , 2017, Maturitas.
[34] K. Yin,et al. Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease. , 2017, American journal of physiology. Heart and circulatory physiology.
[35] E. Claudio,et al. GPER modulates tone and coronary vascular reactivity in male and female rats. , 2017, Journal of molecular endocrinology.
[36] A. Goette,et al. Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men , 2017, Experimental biology and medicine.
[37] I. König,et al. Sex in basic research: concepts in the cardiovascular field. , 2017, Cardiovascular research.
[38] Shannon M. Dunlay,et al. Epidemiology of heart failure with preserved ejection fraction , 2017, Nature Reviews Cardiology.
[39] E. Dworatzek,et al. Targeted basic research to highlight the role of estrogen and estrogen receptors in the cardiovascular system , 2017, Pharmacological research.
[40] E. Morselli,et al. The effects of oestrogens and their receptors on cardiometabolic health , 2017, Nature Reviews Endocrinology.
[41] M. Budoff,et al. Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone , 2017, JAMA.
[42] G. Norton,et al. Sex-Specific Effects of Adrenergic-Induced Left Ventricular Remodeling in Spontaneously Hypertensive Rats. , 2017, Journal of cardiac failure.
[43] I. Barba,et al. High-fat diet induces metabolic changes and reduces oxidative stress in female mouse hearts. , 2017, The Journal of nutritional biochemistry.
[44] M. Estrada,et al. GSK-3β/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy , 2016, PloS one.
[45] E. Levin,et al. Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors , 2016, Nature Reviews Molecular Cell Biology.
[46] G. Hankins,et al. Testosterone downregulates angiotensin II type-2 receptor via androgen receptor-mediated ERK1/2 MAP kinase pathway in rat aorta , 2016, Journal of the renin-angiotensin-aldosterone system : JRAAS.
[47] J. Jose,et al. Testosterone as a marker of coronary artery disease severity in middle aged males , 2016, Indian heart journal.
[48] J. K. Kim,et al. The Role of Estrogen and Estrogen Receptors on Cardiomyocytes: An Overview. , 2016, The Canadian journal of cardiology.
[49] M. L. Porto,et al. Sex differences in the regulation of spatially distinct cardiac mitochondrial subpopulations , 2016, Molecular and Cellular Biochemistry.
[50] Wendy J Mack,et al. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. , 2016, The New England journal of medicine.
[51] E. Murphy,et al. The Expanding Complexity of Estrogen Receptor Signaling in the Cardiovascular System. , 2016, Circulation research.
[52] Susan Cheng,et al. Sex differences in cardiovascular ageing , 2016, Heart.
[53] M. Bauzá-Thorbrügge,et al. GPER mediates the effects of 17β-estradiol in cardiac mitochondrial biogenesis and function , 2016, Molecular and Cellular Endocrinology.
[54] E. Dworatzek,et al. Effects of aging on cardiac extracellular matrix in men and women , 2016, Proteomics. Clinical applications.
[55] J. Oliver,et al. Sexual Dimorphism in the Alterations of Cardiac Muscle Mitochondrial Bioenergetics Associated to the Ageing Process. , 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.
[56] S. Orrù,et al. Molecular effects of supraphysiological doses of doping agents on health. , 2015, Molecular bioSystems.
[57] L. Fu,et al. Testosterone replacement attenuates mitochondrial damage in a rat model of myocardial infarction. , 2015, The Journal of endocrinology.
[58] S. Howlett,et al. Testosterone modulates cardiac contraction and calcium homeostasis: cellular and molecular mechanisms , 2015, Biology of Sex Differences.
[59] Hao Wang,et al. Activation of GPR30 inhibits cardiac fibroblast proliferation , 2015, Molecular and Cellular Biochemistry.
[60] Wei Zhao,et al. MiR-22/Sp-1 Links Estrogens With the Up-Regulation of Cystathionine γ-Lyase in Myocardium, Which Contributes to Estrogenic Cardioprotection Against Oxidative Stress. , 2015, Endocrinology.
[61] Tepmanas Bupha-Intr,et al. Significant role of estrogen in maintaining cardiac mitochondrial functions , 2015, The Journal of Steroid Biochemistry and Molecular Biology.
[62] A. Godoy,et al. Androgen receptor in human endothelial cells. , 2015, The Journal of endocrinology.
[63] Zhuoli Zhang,et al. 17β-estradiol prevents cardiac diastolic dysfunction by stimulating mitochondrial function: A preclinical study in a mouse model of a human hypertrophic cardiomyopathy mutation , 2015, The Journal of Steroid Biochemistry and Molecular Biology.
[64] J. Fuscoe,et al. Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different Ages , 2015, PloS one.
[65] Yang Ruan,et al. SIRT1 Functions as an Important Regulator of Estrogen-Mediated Cardiomyocyte Protection in Angiotensin II-Induced Heart Hypertrophy , 2014, Oxidative medicine and cellular longevity.
[66] V. Regitz-Zagrosek,et al. Sex‐dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload , 2014, European journal of heart failure.
[67] V. Regitz-Zagrosek,et al. Maladaptive remodeling is associated with impaired survival in women but not in men after aortic valve replacement. , 2014, JACC. Cardiovascular imaging.
[68] R. Rose,et al. Sex differences in SR Ca(2+) release in murine ventricular myocytes are regulated by the cAMP/PKA pathway. , 2014, Journal of molecular and cellular cardiology.
[69] Yi‐Jen Chen,et al. Androgen attenuates cardiac fibroblasts activations through modulations of transforming growth factor-β and angiotensin II signaling. , 2014, International journal of cardiology.
[70] D. Vassallo,et al. Na+K+-ATPase Activity and K+ Channels Differently Contribute to Vascular Relaxation in Male and Female Rats , 2014, PloS one.
[71] J. Manson,et al. Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial. , 2014, Annals of internal medicine.
[72] B. Yao,et al. Effects of dihydrotestosterone on adhesion and proliferation via PI3-K/Akt signaling in endothelial progenitor cells , 2014, Endocrine.
[73] M. Guescini,et al. Effects of sex hormones on inflammatory response in male and female vascular endothelial cells , 2014, Journal of Endocrinological Investigation.
[74] Dong I. Lee,et al. PDE5 inhibitor efficacy is estrogen dependent in female heart disease. , 2014, The Journal of clinical investigation.
[75] A. Arnold,et al. The number of X chromosomes influences protection from cardiac ischaemia/reperfusion injury in mice: one X is better than two. , 2014, Cardiovascular research.
[76] C. Pestana,et al. Testosterone induces apoptosis in vascular smooth muscle cells via extrinsic apoptotic pathway with mitochondria-generated reactive oxygen species involvement. , 2014, American journal of physiology. Heart and circulatory physiology.
[77] I. Stefanon,et al. Sex hormones in the cardiovascular system , 2014, Hormone molecular biology and clinical investigation.
[78] T. Hsieh,et al. The Effect of Testosterone on Cardiovascular Disease , 2014, American journal of men's health.
[79] T. McKinsey,et al. Estrogen regulates histone deacetylases to prevent cardiac hypertrophy , 2013, Molecular biology of the cell.
[80] M. Estrada,et al. Testosterone increases GLUT4‐dependent glucose uptake in cardiomyocytes , 2013, Journal of cellular physiology.
[81] V. Regitz-Zagrosek,et al. Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart. , 2013, International journal of cardiology.
[82] R. Karas,et al. Rapid Estrogen Receptor Signaling Mediates Estrogen-Induced Inhibition of Vascular Smooth Muscle Cell Proliferation , 2013, Arteriosclerosis, thrombosis, and vascular biology.
[83] W. Paulus,et al. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. , 2013, Journal of the American College of Cardiology.
[84] R. Karas,et al. Emerging evidence of the importance of rapid, non-nuclear estrogen receptor signaling in the cardiovascular system , 2013, Steroids.
[85] T. Jones,et al. Testosterone: a vascular hormone in health and disease. , 2013, The Journal of endocrinology.
[86] P. Maki,et al. Critical window hypothesis of hormone therapy and cognition: a scientific update on clinical studies , 2013, Menopause.
[87] S. Howlett,et al. Sex differences in mechanisms of cardiac excitation–contraction coupling , 2013, Pflügers Archiv - European Journal of Physiology.
[88] V. Regitz-Zagrosek,et al. 17β-Estradiol-induced interaction of ERα with NPPA regulates gene expression in cardiomyocytes. , 2012, Cardiovascular research.
[89] L. Køber,et al. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial , 2012, BMJ : British Medical Journal.
[90] Masahiro Akishita,et al. Src kinase-mediates androgen receptor-dependent non-genomic activation of signaling cascade leading to endothelial nitric oxide synthase. , 2012, Biochemical and biophysical research communications.
[91] D. Vassallo,et al. Myocardial Contractile Dysfunction Induced by Ovariectomy Requires AT1Receptor Activation in Female Rats , 2012, Cellular Physiology and Biochemistry.
[92] M. Ares,et al. Androgens Contribute to Sex Differences in Myocardial Remodeling under Pressure Overload by a Mechanism Involving TGF-β , 2012, PloS one.
[93] P. Chambon,et al. The role of estrogen receptor α and β in regulating vascular smooth muscle cell proliferation is based on sex. , 2012, The Journal of surgical research.
[94] V. Regitz-Zagrosek,et al. Transcriptome characterization of estrogen-treated human myocardium identifies myosin regulatory light chain interacting protein as a sex-specific element influencing contractile function. , 2012, Journal of the American College of Cardiology.
[95] P. Komesaroff,et al. Physiological effects of androgens on human vascular endothelial and smooth muscle cells in culture , 2011, Steroids.
[96] Saizhu Wu,et al. Testosterone suppresses oxidative stress via androgen receptor-independent pathway in murine cardiomyocytes. , 2011, Molecular medicine reports.
[97] E. Simpson,et al. Aromatase deficiency confers paradoxical postischemic cardioprotection. , 2011, Endocrinology.
[98] Hyung-Seok Kim,et al. Casein Kinase-2&agr;1 Induces Hypertrophic Response by Phosphorylation of Histone Deacetylase 2 S394 and its Activation in the Heart , 2011, Circulation.
[99] G. Nickenig,et al. Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase , 2011, Basic Research in Cardiology.
[100] D. Lubahn,et al. Estrogen receptor-beta prevents cardiac fibrosis. , 2010, Molecular endocrinology.
[101] P. Morris,et al. Low serum testosterone and increased mortality in men with coronary heart disease , 2010, Heart.
[102] A. Jiang,et al. PGC-1 Coactivators in Cardiac Development and Disease , 2010, Circulation research.
[103] M. Flamini,et al. Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo. , 2010, Molecular human reproduction.
[104] RolandHetzer,et al. Regression of Myocardial Hypertrophy After Aortic Valve Replacement , 2010 .
[105] N. Kato,et al. VEGF signaling is disrupted in the hearts of mice lacking estrogen receptor alpha. , 2010, European journal of pharmacology.
[106] H. Randeva,et al. G-protein coupled estrogen receptor 1 expression in rat and human heart: Protective role during ischaemic stress. , 2010, International journal of molecular medicine.
[107] T. Haystead,et al. Smoothelin-like 1 Protein Regulates Myosin Phosphatase-targeting Subunit 1 Expression during Sexual Development and Pregnancy* , 2010, The Journal of Biological Chemistry.
[108] A. Jette,et al. Adverse events associated with testosterone administration. , 2010, The New England journal of medicine.
[109] S. Howlett,et al. Sex differences in mechanisms of cardiac excitation–contraction coupling , 2010, Pflügers Archiv - European Journal of Physiology.
[110] E. Murphy,et al. Sex Differences in the Phosphorylation of Mitochondrial Proteins Result in Reduced Production of Reactive Oxygen Species and Cardioprotection in Females , 2010, Circulation Research.
[111] V. Regitz-Zagrosek,et al. Female sex and estrogen receptor-beta attenuate cardiac remodeling and apoptosis in pressure overload. , 2010, American journal of physiology. Regulatory, integrative and comparative physiology.
[112] Y. Ouchi,et al. Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: role of phosphatidylinositol 3-kinase/akt pathway. , 2010, Endocrinology.
[113] C. Hermenegildo,et al. Estradiol selectively stimulates endothelial prostacyclin production through estrogen receptor-{alpha}. , 2010, Journal of molecular endocrinology.
[114] A. Rousseau,et al. Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects. , 2010, Fertility and sterility.
[115] M. Maggiolini,et al. A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat. , 2009, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
[116] M. Marino,et al. Cell sex determines anoikis resistance in vascular smooth muscle cells , 2009, FEBS letters.
[117] E. Murphy,et al. Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats. , 2009, American journal of physiology. Heart and circulatory physiology.
[118] Seungho Wang,et al. The interaction of estrogen receptor alpha and caveolin-3 regulates connexin43 phosphorylation in metabolic inhibition-treated rat cardiomyocytes. , 2009, The international journal of biochemistry & cell biology.
[119] I. Netuka,et al. Gender Differences in Cardiac Ischemic Injury and Protection—Experimental Aspects , 2009, Experimental biology and medicine.
[120] E. Stefani,et al. Estrogen Contributes to Gender Differences in Mouse Ventricular Repolarization , 2009, Circulation research.
[121] M. Estrada,et al. Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway. , 2009, The Journal of endocrinology.
[122] L. Neyses,et al. Estrogen receptor alpha interacts with 17beta-hydroxysteroid dehydrogenase type 10 in mitochondria. , 2009, Biochemical and biophysical research communications.
[123] J. Hare,et al. Sex‐Specific Impact of Aldosterone Receptor Antagonism on Ventricular Remodeling and Gene Expression after Myocardial Infarction , 2009, Clinical and translational science.
[124] M. Morishima,et al. 17 beta-estradiol modulates expression of low-voltage-activated Ca(V)3.2 T-type calcium channel via extracellularly regulated kinase pathway in cardiomyocytes. , 2009, Endocrinology.
[125] S. Grandy,et al. Expression, Distribution and Regulation of Sex Steroid Hormone Receptors in Mouse Heart , 2009, Cellular Physiology and Biochemistry.
[126] A. Garnier,et al. Transcriptional control of mitochondrial biogenesis: the central role of PGC-1alpha. , 2008, Cardiovascular research.
[127] M. Vannan,et al. Estrogen inhibits cardiac hypertrophy: role of estrogen receptor-beta to inhibit calcineurin. , 2008, Endocrinology.
[128] A. Ahluwalia,et al. Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. , 2008, The Journal of endocrinology.
[129] John J. Evans,et al. Regulation of endothelin-1 release from human endothelial cells by sex steroids and angiotensin-II , 2008, Peptides.
[130] S. Mumby,et al. Direct interactions with G α i and G βγ mediate nongenomic signaling by estrogen receptor α . , 2007, Molecular endocrinology.
[131] P. Roca,et al. Caloric restriction and gender modulate cardiac muscle mitochondrial H2O2 production and oxidative damage. , 2007, Cardiovascular research.
[132] G. Kirilov,et al. Testosterone replacement therapy in male hypogonadism is not associated with increase of endothelin-1 levels. , 2007, International journal of andrology.
[133] C. Foresta,et al. Reduced number of circulating endothelial progenitor cells in hypogonadal men. , 2006, The Journal of clinical endocrinology and metabolism.
[134] E. Stefani,et al. Heart estrogen receptor alpha: distinct membrane and nuclear distribution patterns and regulation by estrogen. , 2006, Journal of molecular and cellular cardiology.
[135] C. Teloken,et al. Diabetes mellitus is associated with subnormal serum levels of free testosterone in men , 2005, BJU international.
[136] Takahiro Matsumoto,et al. Androgen Receptor Gene Knockout Male Mice Exhibit Impaired Cardiac Growth and Exacerbation of Angiotensin II-induced Cardiac Fibrosis* , 2005, Journal of Biological Chemistry.
[137] S. Ito,et al. Marked attenuation of production of collagen type I from cardiac fibroblasts by dehydroepiandrosterone. , 2005, American journal of physiology. Endocrinology and metabolism.
[138] S. Chu,et al. Sex differences in expression of calcium-handling proteins and beta-adrenergic receptors in rat heart ventricle. , 2005, Life sciences.
[139] S. Moncada,et al. Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo , 2005, Circulation.
[140] James A. Clark,et al. Estrogen receptor-β mediates male-female differences in the development of pressure overload hypertrophy , 2005 .
[141] V. Regitz-Zagrosek,et al. Upregulation of Myocardial Estrogen Receptors in Human Aortic Stenosis , 2004, Circulation.
[142] R. Karas,et al. 17&bgr;-Estradiol Reduces Cardiomyocyte Apoptosis In Vivo and In Vitro via Activation of Phospho-Inositide-3 Kinase/Akt Signaling , 2004, Circulation research.
[143] S. Schaefer,et al. Gender modulation of Ca(2+) uptake in cardiac mitochondria. , 2004, Journal of molecular and cellular cardiology.
[144] Y. Jiang,et al. Testosterone Regulates mRNA Levels of Calcium Regulatory Proteins in Cardiac Myocytes , 2004, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[145] David Handelsman,et al. Dihydrotestosterone promotes vascular cell adhesion molecule-1 expression in male human endothelial cells via a nuclear factor-kappaB-dependent pathway. , 2004, Endocrinology.
[146] Anne-Marie Brun-Zinkernagel,et al. Mitochondrial localization of estrogen receptor β , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[147] R. Khalil,et al. Gender, sex hormones, and vascular tone. , 2004, American journal of physiology. Regulatory, integrative and comparative physiology.
[148] J. Isner,et al. Estrogen-Mediated, Endothelial Nitric Oxide Synthase–Dependent Mobilization of Bone Marrow–Derived Endothelial Progenitor Cells Contributes to Reendothelialization After Arterial Injury , 2003, Circulation.
[149] Dan Yang,et al. Mechanisms of 17beta-estradiol on the production of ET-1 in ovariectomized rats. , 2003, Life sciences.
[150] T. Simoncini,et al. Dehydroepiandrosterone modulates endothelial nitric oxide synthesis via direct genomic and nongenomic mechanisms. , 2003, Endocrinology.
[151] Lei Li,et al. Plasma membrane localization and function of the estrogen receptor α variant (ER46) in human endothelial cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[152] Roberto Colombo,et al. Protein carbonyl groups as biomarkers of oxidative stress. , 2003, Clinica chimica acta; international journal of clinical chemistry.
[153] R. Baron,et al. Src Kinase Mediates Phosphatidylinositol 3-Kinase/Akt-dependent Rapid Endothelial Nitric-oxide Synthase Activation by Estrogen* , 2003, The Journal of Biological Chemistry.
[154] T. Kigoshi,et al. Testosterone inhibits tumor necrosis factor‐α‐induced vascular cell adhesion molecule‐1 expression in human aortic endothelial cells , 2002, FEBS letters.
[155] C. Kooperberg,et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. , 2002, JAMA.
[156] T. Mukherjee,et al. Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: Implications in atherosclerosis , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[157] L. Dakovska,et al. Increased plasma endothelin levels in patients with male hypogonadism , 2002, Andrologia.
[158] A. Tedgui,et al. Age and gender effects on cardiomyocyte apoptosis in the normal human heart. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.
[159] Mark A Sussman,et al. Myocardial Akt Activation and Gender: Increased Nuclear Activity in Females Versus Males , 2001, Circulation research.
[160] C. Curl,et al. Effects of gender on intracellular [Ca2+] in rat cardiac myocytes , 2001, Pflügers Archiv.
[161] A. Özer,et al. 17β-Estradiol modulates endothelin-1 expression and release in human endothelial cells , 2000 .
[162] J. Bender,et al. Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[163] E. Vittinghoff,et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. , 1998, JAMA.
[164] C. Grohé,et al. Expression of oestrogen receptor alpha and beta in rat heart: role of local oestrogen synthesis. , 1998, The Journal of endocrinology.
[165] R. Karas,et al. Cardiac myocytes and fibroblasts contain functional estrogen receptors 1 , 1997, FEBS letters.
[166] W. Catterall,et al. Increased Expression of the Cardiac L-type Calcium Channel in Estrogen Receptor–deficient Mice , 1997, The Journal of general physiology.
[167] T. Kumai,et al. Effects of ovariectomy and estrogen replacement on aorta angiotensin-converting enzyme activity in rats. , 1997, Japanese journal of pharmacology.
[168] P. Anversa,et al. Gender differences and aging: effects on the human heart. , 1995, Journal of the American College of Cardiology.
[169] M. Eghbali,et al. Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium. , 1994, Journal of molecular and cellular cardiology.
[170] E. Simpson,et al. Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification. , 1992, The Journal of clinical endocrinology and metabolism.
[171] L. Heywood. Testosterone levels in the male laboratory rat: variation under experimental conditions. , 1980, International journal of andrology.
[172] A. Beale,et al. Sex Differences in Heart Failure with Preserved Ejection Fraction Therapy: Potential Mechanisms and Clinical Implications , 2020 .
[173] E. Jones. Disease , 2020, Palgrave Studies in Economic History.
[174] G. Heyndrickx,et al. Heart Function Analysis in Cardiac Patients with Focus on Sex-Specific Aspects. , 2018, Advances in experimental medicine and biology.
[175] C. Lavie,et al. Testosterone and Cardiovascular Health , 2018, Mayo Clinic proceedings.
[176] Georgios Kararigas,et al. Mechanistic Pathways of Sex Differences in Cardiovascular Disease. , 2017, Physiological reviews.
[177] B. Wan,et al. Dihydrotestosterone modulates endothelial progenitor cell function via RhoA/ROCK pathway. , 2016, American journal of translational research.
[178] J. Houštěk,et al. Sex difference in the sensitivity of cardiac mitochondrial permeability transition pore to calcium load , 2015, Molecular and Cellular Biochemistry.
[179] Richard E. White,et al. Testosterone-induced relaxation of coronary arteries: activation of BKCa channels via the cGMP-dependent protein kinase. , 2012, American journal of physiology. Heart and circulatory physiology.
[180] E. Barrett-Connor,et al. Low serum testosterone and mortality in older men. , 2008, The Journal of clinical endocrinology and metabolism.
[181] Greta L. Hoetzer,et al. Gender differences in circulating endothelial progenitor cell colony-forming capacity and migratory activity in middle-aged adults. , 2007, The American journal of cardiology.
[182] P. Doevendans,et al. Estrogen receptor beta protects the murine heart against left ventricular hypertrophy. , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[183] E. Levin,et al. Estrogen Inhibits Cardiomyocyte Hypertrophy in Vitro : ANTAGONISM OF CALCINEURIN-RELATED HYPERTROPHY THROUGH INDUCTION OF MCIP1* , 2005 .
[184] K. Korach,et al. Estrogen receptor- (cid:1) mediates male-female differences in the development of pressure overload hypertrophy , 2004 .
[185] Anne-Marie Brun-Zinkernagel,et al. Mitochondrial localization of estrogen receptor beta. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[186] E. Levin,et al. ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. , 2002, Molecular endocrinology.
[187] Hong Zhao,et al. Effects of testosterone and 17-beta-estradiol on TNF-alpha-induced E-selectin and VCAM-1 expression in endothelial cells. Analysis of the underlying receptor pathways. , 2002, Life sciences.
[188] M. Ziolo,et al. Mechanisms of sex differences in rat cardiac myocyte response to beta-adrenergic stimulation. , 2002, American journal of physiology. Heart and circulatory physiology.
[189] M. Chappell,et al. Estrogen regulation of angiotensin-converting enzyme mRNA. , 1999, Hypertension.
[190] V. Regitz-Zagrosek,et al. The FASEB Journal • Research Communication Estrogen receptor alpha up-regulation and redistribution in human heart failure , 2022 .
[191] V. Vladimir,et al. Spotlight Issue on Signaling in Cardiac Metabolism: Transcriptional Control of Mitochondrial Biogenesis. the Central Role of Pgc-1α , 2022 .