A new look at dietary carbohydrate: chemistry, physiology and health

The current view of dietary carbohydrates as simply providing us with energy is outdated. Because of their varied chemistry and physical form the rate and extent to which the different types are digested in and absorbed from the small intestine varies. This in turn leads to affects on satiety, blood glucose and insulin, protein glycosylation, lipids and bile acids. Some carbohydrates reach the colon where they are fermented and affect many aspects of large bowel function, colonocyte and hepatic metabolism.  A new framework for classifying and measuring food carbohydrates is needed to allow a greater understanding of the role of individual species in health and to inform the public of their importance. A classification based primarily on molecular size (degree of polymerisation) into sugars, oligosaccharides and polysaccharides, is suggested, with sub-groups identified by the nature of the monosaccharides. Greater knowledge of the chemical and physical properties of carbohydrates allow a more precise relation with physiology and health to be drawn.  The Carbohydrate Group met in Paris in December 1995 at the invitation of Gerard Pascal, Director of CNERNA. Financial support for the meeting was provided by CNERNA.

[1]  A. Cerami,et al.  Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. , 1988, The New England journal of medicine.

[2]  G. Livesey,et al.  Food energy values of dietary fibre components and decreased deposition of body fat. , 1987, International journal of obesity.

[3]  P. Rutgeerts,et al.  13CO2 breath test to measure the hydrolysis of various starch formulations in healthy subjects. , 1990, Gut.

[4]  L. F. Burroughs,et al.  DEPLETION AND DISRUPTION OF DIETARY FIBRE EFFECTS ON SATIETY, PLASMA-GLUCOSE, AND SERUM-INSULIN , 1977, The Lancet.

[5]  D. Southgate Determination of food carbohydrates , 1976 .

[6]  J. Cummings,et al.  Mechanism of action of dietary fibre in the human colon , 1980, Nature.

[7]  M. Roberfroid,et al.  The biochemistry of oligofructose, a nondigestible fiber: an approach to calculate its caloric value. , 2009, Nutrition reviews.

[8]  H. Englyst,et al.  The classification and measurement of dietary carbohydrates , 1996 .

[9]  M. Roberfroid,et al.  Dietary fiber, inulin, and oligofructose: a review comparing their physiological effects. , 1993, Critical reviews in food science and nutrition.

[10]  K. König,et al.  Nutritional role of sugars in oral health. , 1995, The American journal of clinical nutrition.

[11]  G R Gibson,et al.  Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. , 1995, The Journal of nutrition.

[12]  R. D. Lawrence,et al.  CARBOHYDRATE CONTENT OF FOODS , 1932 .

[13]  M. Itakura,et al.  Effects of fructo-oligosaccharides on blood glucose and serum lipids in diabetic subjects , 1984 .

[14]  K. Hermansen,et al.  Differential glycaemic effects of potato, rice and spaghetti in Type 1 (insulin-dependent) diabetic patients at constant insulinaemia , 1986, Diabetologia.

[15]  W. Dills,et al.  Protein fructosylation: fructose and the Maillard reaction. , 1993, The American journal of clinical nutrition.

[16]  D. van Treeck,et al.  Soluble fiber and serum lipids: a literature review. , 1994, Journal of the American Dietetic Association.

[17]  H. Englyst,et al.  Gastrointestinal effects of food carbohydrate. , 1995, The American journal of clinical nutrition.

[18]  J. Durnin,et al.  Calorie conversion factors. An experimental reassessment of the factors used in the calculation of the energy value of human diets , 1970, British Journal of Nutrition.

[19]  S. Bingham,et al.  Digestion and physiological properties of resistant starch in the human large bowel , 1996, British Journal of Nutrition.

[20]  H. Englyst,et al.  Measurement of rapidly available glucose (RAG) in plant foods: a potential in vitro predictor of the glycaemic response , 1996, British Journal of Nutrition.

[21]  J. Rumessen,et al.  Fructans of Jerusalem artichokes: intestinal transport, absorption, fermentation, and influence on blood glucose, insulin, and C-peptide responses in healthy subjects. , 1990, The American journal of clinical nutrition.

[22]  P. Würsch Starch in human nutrition. , 1989, World review of nutrition and dietetics.

[23]  T. Wolever,et al.  Glycemic index of foods: a physiological basis for carbohydrate exchange. , 1981, The American journal of clinical nutrition.

[24]  D. Southgate Digestion and metabolism of sugars. , 1995, The American journal of clinical nutrition.

[25]  W. E. W. ROEDlGER Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man , 2006 .

[26]  N. Asp Classification and methodology of food carbohydrates as related to nutritional effects. , 1995, The American journal of clinical nutrition.

[27]  T. Wolever,et al.  Sugars and blood glucose control. , 1995, The American journal of clinical nutrition.

[28]  H. Dixon Abbreviated terminology of oligosaccharide chains. Recommendations 1980. , 1983, Archives of biochemistry and biophysics.

[29]  J. Van Loo,et al.  On the presence of inulin and oligofructose as natural ingredients in the western diet. , 1995, Critical reviews in food science and nutrition.

[30]  H. Englyst,et al.  Determination of the non-starch polysaccharides in plant foods by gas-liquid chromatography of constituent sugars as alditol acetates. , 1982, The Analyst.

[31]  N. Asp,et al.  Determination of Insoluble and Soluble Dietary Fiber in Foods and Food Products: Collaborative Study , 1992 .

[32]  S. Fry,et al.  MECHANISMS OF ACTION OF DIETARY FIBRE ON LIPID AND CHOLESTEROL METABOLISM , 1993 .

[33]  D. Burkitt,et al.  Refined Carbohydrate Foods and Disease: Some Implications of Dietary Fibre , 1975, Diabetes.

[34]  G R Gibson,et al.  Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. , 1995, Gastroenterology.

[35]  T. Takizawa,et al.  Effects of Fructooligosaccharides on Intestinal Flora and Human Health , 1986 .

[36]  J. Cummings FERMENTATION IN THE HUMAN LARGE INTESTINE: EVIDENCE AND IMPLICATIONS FOR HEALTH , 1983, The Lancet.

[37]  G. Reaven,et al.  Plasma Glucose and Insulin Responses to Orally Administered Simple and Complex Carbohydrates , 1976, Diabetes.

[38]  M. Quigley,et al.  Determination of dietary fibre as non-starch polysaccharides with gas-liquid chromatographic, high-performance liquid chromatographic or spectrophotometric measurement of constituent sugars. , 1994, The Analyst.

[39]  H. Englyst,et al.  Classification and measurement of nutritionally important starch fractions. , 1992, European journal of clinical nutrition.

[40]  K. B. Bach Knudsen,et al.  Recovery of inulin from Jerusalem artichoke (Helianthus tuberosus L.) in the small intestine of man , 1995, British Journal of Nutrition.

[41]  C. Edwards,et al.  Short Chain Fatty Acids , 1999 .

[42]  H. Büller,et al.  Lactose intolerance , 1991, The Lancet.

[43]  A M Prentice,et al.  Sugar and body weight regulation. , 1995, The American journal of clinical nutrition.

[44]  S. Green,et al.  Carbohydrates and human appetite. , 1994, The American journal of clinical nutrition.

[45]  B. Bowman,et al.  Health effects of dietary fructose. , 1993, The American journal of clinical nutrition.

[46]  J. Muir,et al.  Effect of resistant starch on fecal bulk and fermentation-dependent events in humans. , 1995, The American journal of clinical nutrition.

[47]  M. Roberfroid,et al.  Involvement of lipogenesis in the lower VLDL secretion induced by oligofructose in rats , 1996, British Journal of Nutrition.