Oxidant-induced DNA damage by quartz in alveolar epithelial cells.

[1]  Roel P F Schins,et al.  MECHANISMS OF GENOTOXICITY OF PARTICLES AND FIBERS , 2002, Inhalation toxicology.

[2]  David M. Brown,et al.  Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. , 2001, Toxicology and applied pharmacology.

[3]  H Greim,et al.  Toxicity of fibers and particles. Report of the workshop held in Munich, Germany, 26-27 October 2000. , 2001, Inhalation toxicology.

[4]  F. Seiler,et al.  Quartz exposure of the rat lung leads to a linear dose response in inflammation but not in oxidative DNA damage and mutagenicity. , 2001, American journal of respiratory cell and molecular biology.

[5]  J. Paulauskis,et al.  Endocytosis of ultrafine particles by A549 cells. , 2001, American journal of respiratory cell and molecular biology.

[6]  M. O’Reilly,et al.  Pulmonary chemokine and mutagenic responses in rats after subchronic inhalation of amorphous and crystalline silica. , 2000, Toxicological sciences : an official journal of the Society of Toxicology.

[7]  L. Marnett,et al.  Oxyradicals and DNA damage. , 2000, Carcinogenesis.

[8]  T. Hei,et al.  Role of oxyradicals in mutagenicity and DNA damage induced by crocidolite asbestos in mammalian cells. , 1999, Cancer research.

[9]  Zhuo Zhang,et al.  Critical role of GSH in silica-induced oxidative stress, cytotoxicity, and genotoxicity in alveolar macrophages. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[10]  P. Borm,et al.  Neutrophils cause oxidative DNA damage in alveolar epithelial cells. , 1999, Free radical biology & medicine.

[11]  B. Fubini Surface chemistry and quartz hazard , 1998 .

[12]  W. Wallace,et al.  Phospholipid surfactant adsorption by respirable quartz and in vitro expression of cytotoxicity and DNA damage. , 1998, Toxicology letters.

[13]  V. Castranova,et al.  Reactive oxygen species and silica-induced carcinogenesis. , 1998, Journal of toxicology and environmental health. Part B, Critical reviews.

[14]  P. Borm,et al.  The quartz hazard: a variable entity. , 1998, The Annals of occupational hygiene.

[15]  Bindu Raju,et al.  Silica, Some Silicates, Coal Dust and Para-aramid Fibrils. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 68 , 1998, Cancer Causes & Control.

[16]  W. Whong,et al.  Detection of mineral-dust-induced DNA damage in two mammalian cell lines using the alkaline single cell gel/comet assay. , 1997, Mutation research.

[17]  F. Seiler,et al.  Formation and persistence of 8-oxoguanine in rat lung cells as an important determinant for tumor formation following particle exposure. , 1997, Environmental health perspectives.

[18]  S. Linn,et al.  Formation, Prevention, and Repair of DNA Damage by Iron/Hydrogen Peroxide* , 1997, The Journal of Biological Chemistry.

[19]  R. V. van Klaveren,et al.  Involvement of an NAD(P)H oxidase-like enzyme in superoxide anion and hydrogen peroxide generation by rat type II cells. , 1997, Thorax.

[20]  H. Ochi,et al.  Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model. , 1997, Laboratory investigation; a journal of technical methods and pathology.

[21]  J. Carter,et al.  Effects of particle exposure and particle-elicited inflammatory cells on mutation in rat alveolar epithelial cells. , 1997, Carcinogenesis.

[22]  P. Borm,et al.  Particles, inflammation and respiratory tract carcinogenesis. , 1996, Toxicology letters.

[23]  A. Churg,et al.  The uptake of mineral particles by pulmonary epithelial cells. , 1996, American journal of respiratory and critical care medicine.

[24]  J. Carter,et al.  Characterizing mutagenesis in the hprt gene of rat alveolar epithelial cells. , 1995, Experimental lung research.

[25]  C. Cross,et al.  DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells , 1995, FEBS letters.

[26]  X. Shi,et al.  DNA strand breakage, thymine glycol production, and hydroxyl radical generation induced by different samples of crystalline silica in vitro. , 1995, Environmental research.

[27]  J. Nath,et al.  Silica-induced micronuclei and chromosomal aberrations in Chinese hamster lung (V79) and human lung (Hel 299) cells. , 1995, Mutation research.

[28]  S. Tsugane,et al.  Oxidative DNA damage induced by silica in vivo. , 1995, Environmental research.

[29]  B. Gilks,et al.  Rat mesothelial and tracheal epithelial cells show equal DNA sensitivity to hydrogen peroxide-induced oxidant injury. , 1995, The American journal of physiology.

[30]  U Saffiotti,et al.  Silica radical-induced DNA damage and lipid peroxidation. , 1994, Environmental health perspectives.

[31]  X. Shi,et al.  Mechanisms of carcinogenesis by crystalline silica in relation to oxygen radicals. , 1994, Environmental health perspectives.

[32]  U Saffiotti,et al.  Oxidative DNA damage by crystalline silica. , 1993, Free radical biology & medicine.

[33]  L. Loeb,et al.  8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. , 1992, The Journal of biological chemistry.

[34]  J. Crapo,et al.  Hydrogen peroxide production by alveolar type II cells, alveolar macrophages, and endothelial cells. , 1991, The American journal of physiology.

[35]  M Volante,et al.  Chemical functionalities at the silica surface determining its reactivity when inhaled. Formation and reactivity of surface radicals. , 1990, Toxicology and industrial health.

[36]  P. Olive,et al.  Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the “Comet” Assay , 1990 .

[37]  Xianglin Shi,et al.  Generation of free radicals from freshly fractured silica dust. Potential role in acute silica-induced lung injury. , 1988, The American review of respiratory disease.

[38]  J. Jackson,et al.  Oxidant-induced DNA damage of target cells. , 1988, The Journal of clinical investigation.

[39]  R. Tice,et al.  A simple technique for quantitation of low levels of DNA damage in individual cells. , 1988, Experimental cell research.

[40]  J. Barrett,et al.  Dependence of asbestos- and mineral dust-induced transformation of mammalian cells in culture on fiber dimension. , 1984, Cancer research.

[41]  A. Brody,et al.  Deposition and translocation of inhaled silica in rats. Quantification of particle distribution, macrophage participation, and function. , 1982, Laboratory investigation; a journal of technical methods and pathology.

[42]  Barry H. Smith,et al.  A continuous tumor‐cell line from a human lung carcinoma with properties of type II alveolar epithelial cells , 1976, International journal of cancer.

[43]  R. Tice,et al.  Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing , 2000, Environmental and molecular mutagenesis.

[44]  J. Spencer,et al.  Hydrogen peroxide induces oxidative DNA damage in rat type II pulmonary epithelial cells , 1999, Environmental and molecular mutagenesis.

[45]  U Saffiotti,et al.  Direct interaction between crystalline silica and DNA - a proposed model for silica carcinogenesis. , 1995, Scandinavian journal of work, environment & health.

[46]  J. Nath,et al.  チャイニーズハムスター肺(V79)細胞とヒト肺(Hel299)細胞における,シリカにより誘発される小核と染色体異常 , 1995 .

[47]  M Volante,et al.  Physicochemical properties of crystalline silica dusts and their possible implication in various biological responses. , 1995, Scandinavian journal of work, environment & health.

[48]  W. W. Nichols,et al.  Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: Analysis by pulsed field gel electrophoresis and implications for alkaline elution assays , 1994, Environmental and molecular mutagenesis.

[49]  W. Pryor Why is the hydroxyl radical the only radical that commonly adds to DNA? Hypothesis: it has a rare combination of high electrophilicity, high thermochemical reactivity, and a mode of production that can occur near DNA. , 1988, Free radical biology & medicine.

[50]  L. M. Holland,et al.  Silica-induced alveolar cell tumors in rats. , 1987, American journal of industrial medicine.