Natural Inhibitors of Snake Venom Metallopeptidases

[1]  Magno Junqueira,et al.  Unraveling the processing and activation of snake venom metalloproteinases. , 2014, Journal of proteome research.

[2]  A. Mukherjee,et al.  Characterization of a Kunitz-type protease inhibitor peptide (Rusvikunin) purified from Daboia russelii russelii venom. , 2014, International journal of biological macromolecules.

[3]  J. Huntington Natural inhibitors of thrombin , 2014, Thrombosis and Haemostasis.

[4]  S. Serrano,et al.  Interaction of Bothrops jararaca venom metalloproteinases with protein inhibitors. , 2014, Toxicon : official journal of the International Society on Toxinology.

[5]  N. Cerdà-Costa,et al.  Architecture and function of metallopeptidase catalytic domains , 2014, Protein science : a publication of the Protein Society.

[6]  M. S. Luna,et al.  Activation of Bothrops jararaca snake venom gland and venom production: a proteomic approach. , 2013, Journal of proteomics.

[7]  J. Calvete Snake venomics: from the inventory of toxins to biology. , 2013, Toxicon : official journal of the International Society on Toxinology.

[8]  Jian-yin Lin,et al.  Recombinant snake venom metalloproteinase inhibitor BJ46A inhibits invasion and metastasis of B16F10 and MHCC97H cells through reductions of matrix metalloproteinases 2 and 9 activities , 2013, Anti-cancer drugs.

[9]  W. Wüster,et al.  Complex cocktails: the evolutionary novelty of venoms. , 2013, Trends in ecology & evolution.

[10]  F. Markland,et al.  Snake venom metalloproteinases. , 2013, Toxicon : official journal of the International Society on Toxinology.

[11]  S. Jansa,et al.  Snake‐venom resistance as a mammalian trophic adaptation: lessons from didelphid marsupials , 2012, Biological reviews of the Cambridge Philosophical Society.

[12]  N. Casewell On the ancestral recruitment of metalloproteinases into the venom of snakes. , 2012, Toxicon : official journal of the International Society on Toxinology.

[13]  J. Perales,et al.  Using mass spectrometry to explore the neglected glycan moieties of the antiophidic proteins DM43 and DM64 , 2012, Proteomics.

[14]  E. Pérez-Payá,et al.  Identification of new snake venom metalloproteinase inhibitors using compound screening and rational Peptide design. , 2012, ACS medicinal chemistry letters.

[15]  C. Robinson,et al.  The interaction of the antitoxin DM43 with a snake venom metalloproteinase analyzed by mass spectrometry and surface plasmon resonance. , 2012, Journal of mass spectrometry : JMS.

[16]  P. Ho,et al.  Venomics profiling of Thamnodynastes strigatus unveils matrix metalloproteinases and other novel proteins recruited to the toxin arsenal of rear-fanged snakes. , 2012, Journal of proteome research.

[17]  Alex Bateman,et al.  MEROPS: the database of proteolytic enzymes, their substrates and inhibitors , 2011, Nucleic Acids Res..

[18]  S. Terada,et al.  Novel Function of Antihemorrhagic Factor HSF as an SSP-Binding Protein in Habu (Trimeresurus flavoviridis) Serum , 2011 .

[19]  J. Fox,et al.  Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases. , 2011, Journal of proteomics.

[20]  C. Salas,et al.  Plant proteinases and inhibitors: an overview of biological function and pharmacological activity. , 2011, Current protein & peptide science.

[21]  S. Jansa,et al.  Adaptive Evolution of the Venom-Targeted vWF Protein in Opossums that Eat Pitvipers , 2011, PloS one.

[22]  N. Rawlings Peptidase inhibitors in the MEROPS database. , 2010, Biochimie.

[23]  C. Scott,et al.  Biologic protease inhibitors as novel therapeutic agents. , 2010, Biochimie.

[24]  K. Ikeda,et al.  Up-regulation of the expressions of phospholipase A2 inhibitors in the liver of a venomous snake by its own venom phospholipase A2. , 2010, Biochemical and biophysical research communications.

[25]  A. Yarlequé,et al.  The novel metalloproteinase atroxlysin-I from Peruvian Bothrops atrox (Jergón) snake venom acts both on blood vessel ECM and platelets. , 2010, Archives of biochemistry and biophysics.

[26]  A. Johnsen,et al.  Human CRISP-3 binds serum alpha(1)B-glycoprotein across species. , 2010, Biochimica et biophysica acta.

[27]  C. Garlanda,et al.  An integrated view of humoral innate immunity: pentraxins as a paradigm. , 2010, Annual review of immunology.

[28]  J. Fox,et al.  Proteomic profiling of snake venom metalloproteinases (SVMPs): insights into venom induced pathology. , 2009, Toxicon : official journal of the International Society on Toxinology.

[29]  S. Ferreira,et al.  Conformational plasticity of DM43, a metalloproteinase inhibitor from Didelphis marsupialis: chemical and pressure-induced equilibrium (un)folding studies. , 2009, Biochimica et biophysica acta.

[30]  M. Deshimaru,et al.  Snake fetuin: isolation and structural analysis of new fetuin family proteins from the sera of venomous snakes. , 2009, Toxicon : official journal of the International Society on Toxinology.

[31]  J. Fox,et al.  Snake Venom Metalloproteinases , 2009 .

[32]  G. Domont,et al.  Crotalid snake venom subproteomes unraveled by the antiophidic protein DM43. , 2009, Journal of proteome research.

[33]  Kiyoshi Ikeda,et al.  Up-regulation of the expression of leucine-rich α2-glycoprotein in hepatocytes by the mediators of acute-phase response , 2009, Biochemical and Biophysical Research Communications.

[34]  P. Ho,et al.  Bothrops insularis venomics: a proteomic analysis supported by transcriptomic-generated sequence data. , 2009, Journal of proteomics.

[35]  L. van der Weerd,et al.  Evolution and diversification of the Toxicofera reptile venom system. , 2009, Journal of proteomics.

[36]  F. Gomis-Rüth Catalytic Domain Architecture of Metzincin Metalloproteases* , 2009, The Journal of Biological Chemistry.

[37]  J. Fox,et al.  Insights into and speculations about snake venom metalloproteinase (SVMP) synthesis, folding and disulfide bond formation and their contribution to venom complexity , 2008, The FEBS journal.

[38]  M. Deshimaru,et al.  Properties and cDNA cloning of antihemorrhagic factors in sera of Chinese and Japanese mamushi (Gloydius blomhoffi). , 2008, Toxicon : official journal of the International Society on Toxinology.

[39]  J. Gutiérrez,et al.  Trends in snakebite envenomation therapy: scientific, technological and public health considerations. , 2007, Current pharmaceutical design.

[40]  M. Deshimaru,et al.  Active fragments of the antihemorrhagic protein HSF from serum of habu (Trimeresurus flavoviridis). , 2007, Toxicon : official journal of the International Society on Toxinology.

[41]  R. Theakston,et al.  Neutralization of the haemorrhagic activities of viperine snake venoms and venom metalloproteinases using synthetic peptide inhibitors and chelators. , 2007, Toxicon : official journal of the International Society on Toxinology.

[42]  S. Takeda,et al.  Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C‐shaped scaffold , 2006, The EMBO journal.

[43]  M. Ohno,et al.  Properties and cDNA cloning of an antihemorrhagic factor (HSF) purified from the serum of Trimeresurus flavoviridis. , 2005, Toxicon : official journal of the International Society on Toxinology.

[44]  J. Fox,et al.  Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases. , 2005, Toxicon : official journal of the International Society on Toxinology.

[45]  J. Gutiérrez,et al.  Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage. , 2005, Toxicon : official journal of the International Society on Toxinology.

[46]  G. Domont,et al.  Natural inhibitors of snake venom hemorrhagic metalloproteinases. , 2005, Toxicon : official journal of the International Society on Toxinology.

[47]  Lars Kjeldsen,et al.  Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. , 2004, Biochemistry.

[48]  David G Myszka,et al.  Characterizing high-affinity antigen/antibody complexes by kinetic- and equilibrium-based methods. , 2004, Analytical biochemistry.

[49]  Neil D Rawlings,et al.  Evolutionary families of peptidase inhibitors. , 2004, The Biochemical journal.

[50]  J. Gutiérrez,et al.  Snake venom metalloproteinases: structure/function relationships studies using monoclonal antibodies. , 2003, Toxicon : official journal of the International Society on Toxinology.

[51]  G. Domont,et al.  Natural phospholipase A(2) myotoxin inhibitor proteins from snakes, mammals and plants. , 2003, Toxicon : official journal of the International Society on Toxinology.

[52]  G. Domont,et al.  PO41, a snake venom metalloproteinase inhibitor isolated from Philander opossum serum. , 2003, Toxicon : official journal of the International Society on Toxinology.

[53]  S. Serrano,et al.  Molecular cloning and expression of structural domains of bothropasin, a P-III metalloproteinase from the venom of Bothrops jararaca. , 2003, Toxicon : official journal of the International Society on Toxinology.

[54]  J. M. Gutierrez,et al.  Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum. , 2002, European journal of biochemistry.

[55]  J. Fox,et al.  Structural and Functional Analyses of DM43, a Snake Venom Metalloproteinase Inhibitor from Didelphis marsupialisSerum* , 2002, The Journal of Biological Chemistry.

[56]  M. R. McKeller,et al.  The effects of Western Diamondback Rattlesnake (Crotalus atrox) venom on the production of antihemorrhagins and/or antibodies in the Virginia opossum (Didelphis virginiana). , 2002, Toxicon : official journal of the International Society on Toxinology.

[57]  J. Fox,et al.  BJ46a, a snake venom metalloproteinase inhibitor. Isolation, characterization, cloning and insights into its mechanism of action. , 2001, European journal of biochemistry.

[58]  D. Mebs,et al.  The antihemorrhagic factor, erinacin, from the European hedgehog (Erinaceus europaeus), a metalloprotease inhibitor of large molecular size possessing ficolin/opsonin P35 lectin domains. , 2000, Toxicon : official journal of the International Society on Toxinology.

[59]  G. Faure,et al.  Natural inhibitors of toxic phospholipases A(2). , 2000, Biochimie.

[60]  J. Gutiérrez,et al.  Effectiveness of batimastat, a synthetic inhibitor of matrix metalloproteinases, in neutralizing local tissue damage induced by BaP1, a hemorrhagic metalloproteinase from the venom of the snake bothrops asper. , 2000, Biochemical pharmacology.

[61]  G. Domont,et al.  Isolation and characterization of DM40 and DM43, two snake venom metalloproteinase inhibitors from Didelphis marsupialis serum. , 2000, Biochimica et biophysica acta.

[62]  R. Huber,et al.  Structural basis of the endoproteinase-protein inhibitor interaction. , 2000, Biochimica et biophysica acta.

[63]  J. Gutiérrez,et al.  Citrate inhibition of snake venom proteases. , 1998, Toxicon : official journal of the International Society on Toxinology.

[64]  P. Gopalakrishnakone,et al.  Snake envenomation and protective natural endogenous proteins: a mini review of the recent developments (1991-1997). , 1998, Toxicon : official journal of the International Society on Toxinology.

[65]  D. K. Smith,et al.  Sequence profiles of immunoglobulin and immunoglobulin-like domains. , 1997, Journal of molecular biology.

[66]  G. Domont,et al.  Inhibitory properties of the antibothropic complex from the South American opossum (Didelphis marsupialis) serum. , 1997, Toxicon : official journal of the International Society on Toxinology.

[67]  J. Fox,et al.  Expression, activation, and processing of the recombinant snake venom metalloproteinase, pro-atrolysin E. , 1996, Archives of biochemistry and biophysics.

[68]  G. Domont,et al.  Isolation of protein factors from opossum (Didelphis albiventris) serum which protect against Bothrops jararaca venom. , 1996, Toxicon : official journal of the International Society on Toxinology.

[69]  S. Jones,et al.  Principles of protein-protein interactions. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[70]  Z. Qi,et al.  Characterization of the antihemorrhagic factors of mongoose (Herpestes edwardsii). , 1994, Toxicon : official journal of the International Society on Toxinology.

[71]  M. Paine,et al.  Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family. , 1992, The Journal of biological chemistry.

[72]  Y. Yamakawa,et al.  Primary structure of the antihemorrhagic factor in serum of the Japanese Habu: a snake venom metalloproteinase inhibitor with a double-headed cystatin domain. , 1992, Journal of biochemistry.

[73]  Z. Vogel,et al.  How the mongoose can fight the snake: the binding site of the mongoose acetylcholine receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[74]  J. Catanese,et al.  Isolation from opossum serum of a metalloproteinase inhibitor homologous to human alpha 1B-glycoprotein. , 1992, Biochemistry.

[75]  J. Fox,et al.  Interaction of hemorrhagic metalloproteinases with human alpha 2-macroglobulin. , 1990, Biochemistry.

[76]  M. Horowitz,et al.  Snake acetylcholine receptor: cloning of the domain containing the four extracellular cysteines of the alpha subunit. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[77]  E. Auerswald,et al.  The arrangement of disulfide loops in human alpha 2-HS glycoprotein. Similarity to the disulfide bridge structures of cystatins and kininogens. , 1989, The Journal of biological chemistry.

[78]  N. Ishioka,et al.  Amino acid sequence of human plasma alpha 1B-glycoprotein: homology to the immunoglobulin supergene family. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[79]  S. Magnusson,et al.  Primary structure of human alpha 2-macroglobulin. V. The complete structure. , 1984, The Journal of biological chemistry.

[80]  J. Fox,et al.  Proteolytic specificity and cobalt exchange of hemorrhagic toxin e, a zinc protease isolated from the venom of the western diamondback rattlesnake (Crotalus atrox). , 1983, Biochemistry.

[81]  Eiki Ogawa,et al.  Small serum protein-1 changes the susceptibility of an apoptosis-inducing metalloproteinase HV1 to a metalloproteinase inhibitor in habu snake (Trimeresurus flavoviridis). , 2013, Journal of biochemistry.

[82]  F. Gomis-Rüth,et al.  Matrix metalloproteinases: fold and function of their catalytic domains. , 2010, Biochimica et biophysica acta.

[83]  K. Brew,et al.  The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. , 2010, Biochimica et biophysica acta.

[84]  S. Mackessy,et al.  Reptile venom glands: form, function, and future. , 2009 .

[85]  G. Domont,et al.  Natural inhibitors: innate immunity to snake venoms. , 2009 .

[86]  A. Sali,et al.  Integrating diverse data for structure determination of macromolecular assemblies. , 2008, Annual review of biochemistry.

[87]  G. Domont,et al.  Detection of an antibothropic fraction in opossum (Didelphis marsupialis) milk that neutralizes Bothrops jararaca venom. , 1999, Toxicon : official journal of the International Society on Toxinology.

[88]  J. Bieth Theoretical and practical aspects of proteinase inhibition kinetics. , 1995, Methods in enzymology.

[89]  J. Fox,et al.  Hemorrhagic metalloproteinases from snake venoms. , 1994, Pharmacology & therapeutics.

[90]  G. Domont,et al.  Natural anti-snake venom proteins. , 1991, Toxicon : official journal of the International Society on Toxinology.

[91]  A. F. Williams,et al.  The immunoglobulin superfamily--domains for cell surface recognition. , 1988, Annual review of immunology.

[92]  C. A. Wit,et al.  Purification and characterization of α2-, α2-β- and β-macroglobulin inhibitors in the hedgehog, Erinaceus europaeus: β-macroglobulin identified as the plasma antihemorrhagic factor , 1987 .

[93]  J. Perales,et al.  Isolation and partial characterization of a protein fraction from the opossum (Didelphis marsupialis) serum, with protecting property against the Bothrops jararaca snake venom. , 1986, Anais da Academia Brasileira de Ciencias.

[94]  I. Kato,et al.  Protein inhibitors of proteinases. , 1980, Annual review of biochemistry.