The role of NOD-like Receptors in shaping adaptive immunity.

[1]  S. Diebold Innate recognition of viruses. , 2010, Immunology letters.

[2]  F. Sutterwala,et al.  Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome , 2009, Proceedings of the National Academy of Sciences.

[3]  Dan R. Littman,et al.  Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria , 2009, Cell.

[4]  J. Tschopp,et al.  Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors , 2009, Nature Medicine.

[5]  Yusuke Nakamura,et al.  Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. , 2009, The Journal of allergy and clinical immunology.

[6]  Philippa Marrack,et al.  Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity1 , 2009, The Journal of Immunology.

[7]  渡部 英基 Danger Signaling through the Inflammasome Acts as a Master Switch between Tolerance and Sensitization , 2009 .

[8]  L. Joosten,et al.  Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF1 , 2009, The Journal of Immunology.

[9]  F. Re,et al.  Cutting Edge: Necrosis Activates the NLRP3 Inflammasome1 , 2009, The Journal of Immunology.

[10]  S. Cullen,et al.  Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. , 2009, Immunity.

[11]  G. Núñez,et al.  Cutting Edge: TNF-α Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation1 , 2009, The Journal of Immunology.

[12]  E. Alnemri,et al.  Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1 , 2009, The Journal of Immunology.

[13]  J. Pfeilschifter,et al.  Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors* , 2009, The Journal of Biological Chemistry.

[14]  E. Sousa,et al.  Innate recognition of viruses , 2009 .

[15]  D. Kastner,et al.  Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity. , 2009, Immunity.

[16]  Fuping Zhang,et al.  A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. , 2009, Immunity.

[17]  J. Girard,et al.  The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1 , 2009, Proceedings of the National Academy of Sciences.

[18]  Richard A Flavell,et al.  Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. , 2009, Vaccine.

[19]  J. Bertin,et al.  NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury* , 2009, Journal of Biological Chemistry.

[20]  R. Webby,et al.  The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. , 2009, Immunity.

[21]  J. Ting,et al.  The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. , 2009, Immunity.

[22]  P. Marrack,et al.  Towards an understanding of the adjuvant action of aluminium , 2009, Nature Reviews Immunology.

[23]  F. Martinon,et al.  The inflammasomes: guardians of the body. , 2009, Annual review of immunology.

[24]  J. Tschopp,et al.  Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome , 2009, Proceedings of the National Academy of Sciences.

[25]  Akiko Iwasaki,et al.  Inflammasome recognition of influenza virus is essential for adaptive immune responses , 2009, The Journal of experimental medicine.

[26]  T. Vanden Berghe,et al.  Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes *S , 2008, Molecular & Cellular Proteomics.

[27]  H. Hammad,et al.  Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome , 2008, The Journal of Immunology.

[28]  K. Rock,et al.  Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.

[29]  G. Núñez,et al.  The Nlrp3 inflammasome is critical for aluminium hydroxide‐mediated IL‐1β secretion but dispensable for adjuvant activity , 2008, European journal of immunology.

[30]  F. Re,et al.  Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP31 , 2008, The Journal of Immunology.

[31]  Richard A. Flavell,et al.  Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants , 2008, Nature.

[32]  C. Gabay,et al.  IL‐1, IL‐18, and IL‐33 families of cytokines , 2008, Immunological reviews.

[33]  J. Tschopp,et al.  Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica , 2008, Science.

[34]  Henk C. Hoogsteden,et al.  Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells , 2008, The Journal of experimental medicine.

[35]  Lois J. Maltais,et al.  The NLR gene family: a standard nomenclature. , 2008, Immunity.

[36]  S. Werner,et al.  Active Caspase-1 Is a Regulator of Unconventional Protein Secretion , 2008, Cell.

[37]  L. Santambrogio,et al.  Anthrax Lethal Toxin Triggers the Formation of a Membrane-Associated Inflammasome Complex in Murine Macrophages , 2009, Infection and Immunity.

[38]  Gabriel Núñez,et al.  Frontline : Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation , 2007 .

[39]  R. Flavell,et al.  Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. , 2007, Cell host & microbe.

[40]  F. Martinon,et al.  Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration , 2007, Cell Death and Differentiation.

[41]  E. Alnemri,et al.  The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation , 2007, Cell Death and Differentiation.

[42]  D. Philpott,et al.  Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. , 2007, Immunity.

[43]  Sheri L. Riccardi,et al.  NALP1 in vitiligo-associated multiple autoimmune disease. , 2007, The New England journal of medicine.

[44]  Graham F. Brady,et al.  Regulation of Legionella Phagosome Maturation and Infection through Flagellin and Host Ipaf* , 2006, Journal of Biological Chemistry.

[45]  B. Cookson,et al.  Caspase‐1‐dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages , 2006, Cellular microbiology.

[46]  S. Akira,et al.  Toll-like receptors and innate immunity , 2006, Journal of Molecular Medicine.

[47]  Alan Aderem,et al.  Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf , 2006, Nature Immunology.

[48]  F. Martinon,et al.  Gout-associated uric acid crystals activate the NALP3 inflammasome , 2006, Nature.

[49]  S. Akira,et al.  Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3 , 2006, Nature.

[50]  V. Dixit,et al.  Cryopyrin activates the inflammasome in response to toxins and ATP , 2006, Nature.

[51]  J. Bertin,et al.  Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. , 2006, Immunity.

[52]  W. Dietrich,et al.  Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin , 2006, Nature Genetics.

[53]  Richard A. Flavell,et al.  Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract , 2005, Science.

[54]  James E. Evans,et al.  Molecular identification of a danger signal that alerts the immune system to dying cells , 2003, Nature.

[55]  F. Martinon,et al.  The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. , 2002, Molecular cell.

[56]  A. Gabrielli,et al.  Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1 , NALP-3 and IPAF , 2022 .