Perforin deficiency attenuates inflammation and tumor growth in colitis‐associated cancer
暂无分享,去创建一个
M. Neurath | P. Galle | M. Schuler | S. Wirtz | M. Waldner | C. Becker | D. Seidel | I. Tubbe | P. Hähnel | K. Cappel
[1] M. Neurath,et al. The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6. , 2008, The Journal of clinical investigation.
[2] A. Jemal,et al. Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.
[3] C. Harris,et al. Inflammation and cancer: An ancient link with novel potentials , 2007, International journal of cancer.
[4] T. Ley,et al. Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance. , 2007, Immunity.
[5] Markus F Neurath,et al. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression , 2007, Nature Protocols.
[6] M. Neurath,et al. The T-box transcription factor eomesodermin controls CD8 T cell activity and lymph node metastasis in human colorectal cancer , 2007, Gut.
[7] G. Rabinovich,et al. Immunosuppressive strategies that are mediated by tumor cells. , 2007, Annual review of immunology.
[8] Stefan Wirtz,et al. Chemically induced mouse models of intestinal inflammation , 2007, Nature Protocols.
[9] Maximilian Waldner,et al. Colon cancer and the immune system: the role of tumor invading T cells. , 2006, World journal of gastroenterology.
[10] A. Filipovich. Hemophagocytic lymphohistiocytosis and related disorders , 2006, Current opinion in allergy and clinical immunology.
[11] J. Ferlay,et al. Estimates of the cancer incidence and mortality in Europe in 2006. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.
[12] Z. Trajanoski,et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. , 2005, The New England journal of medicine.
[13] H A Lehr,et al. In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy , 2005, Gut.
[14] C. Elia,et al. Apoptosis in the intestinal mucosa of patients with inflammatory bowel disease: evidence of altered expression of FasL and perforin cytotoxic pathways , 2005, International Journal of Colorectal Disease.
[15] T. Ley,et al. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. , 2004, Immunity.
[16] Stefan Wirtz,et al. TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling , 2004 .
[17] Hans Clevers,et al. At the Crossroads of Inflammation and Cancer , 2004, Cell.
[18] R. Kiesslich,et al. TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. , 2004, Immunity.
[19] R. Schreiber,et al. The immunobiology of cancer immunosurveillance and immunoediting. , 2004, Immunity.
[20] Å. Danielsson,et al. Cytolytic Capabilities of Lamina Propria and Intraepithelial Lymphocytes in Normal and Chronically Inflamed Human Intestine , 2004, Scandinavian journal of immunology.
[21] E. Bergmann-Leitner,et al. Identification and targeting of tumor escape mechanisms: a new hope for cancer therapy? , 2003, Current pharmaceutical design.
[22] M. Neurath,et al. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. , 2003, The Journal of clinical investigation.
[23] J. Henter. Biology and treatment of familial hemophagocytic lymphohistiocytosis: importance of perforin in lymphocyte-mediated cytotoxicity and triggering of apoptosis. , 2002, Medical and pediatric oncology.
[24] E. Wisse,et al. Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells , 2001, Cancer Immunology, Immunotherapy.
[25] K. Abrams,et al. The risk of colorectal cancer in ulcerative colitis: a meta-analysis , 2001, Gut.
[26] H Nagura,et al. CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. , 1998, Cancer research.
[27] W. Lutz,et al. Decreased tumor surveillance in perforin-deficient mice , 1996, The Journal of experimental medicine.
[28] D. Sachar,et al. Cancer in Crohn's disease: dispelling the myths. , 1994, Gut.
[29] Hans Hengartner,et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice , 1994, Nature.
[30] A. House,et al. Survival and the immune response in patients with carcinoma of the colorectum. , 1979, Gut.
[31] A. House,et al. Colonic carcinoma. A quantitative assessment of lymphocyte infiltration at the periphery of colonic tumors related to prognosis , 1978, Cancer.
[32] D. Jäger,et al. [Systemic therapy for colorectal cancer]. , 2005, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.
[33] L. Mazzucchelli,et al. Activated CD4+ and CD8+ cytotoxic cells are present in increased numbers in the intestinal mucosa from patients with active inflammatory bowel disease. , 1998, The American journal of pathology.
[34] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.
[35] Wallack Mk. Immunotherapy in colorectal cancer. , 1981, Missouri medicine.