Egr1 mediates the effect of insulin on leptin transcription in adipocytes
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[1] Adam T. Labadorf,et al. Chromatin Immunoprecipitation of Murine Brown Adipose Tissue. , 2018, Journal of visualized experiments : JoVE.
[2] S. Shin,et al. Leptin is a direct transcriptional target of EGR1 in human breast cancer cells , 2018, Molecular Biology Reports.
[3] Kornel Labun,et al. Accurate analysis of genuine CRISPR editing events with ampliCan , 2018, bioRxiv.
[4] P. Bickel,et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function , 2016, Nature Communications.
[5] Ana I. Domingos,et al. Sympathetic Neuro-adipose Connections Mediate Leptin-Driven Lipolysis , 2015, Cell.
[6] K. Kandror,et al. 4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL* , 2015, The Journal of Biological Chemistry.
[7] Neville E. Sanjana,et al. Improved vectors and genome-wide libraries for CRISPR screening , 2014, Nature Methods.
[8] R. T. Pickering,et al. Fat-specific Protein 27 Inhibits Lipolysis by Facilitating the Inhibitory Effect of Transcription Factor Egr1 on Transcription of Adipose Triglyceride Lipase* , 2014, The Journal of Biological Chemistry.
[9] Dudley Lamming,et al. A Central role for mTOR in lipid homeostasis. , 2013, Cell metabolism.
[10] Yuanyuan Wu,et al. Insulin Inhibits Lipolysis in Adipocytes via the Evolutionarily Conserved mTORC1-Egr1-ATGL-Mediated Pathway , 2013, Molecular and Cellular Biology.
[11] C. Mantzoros,et al. Leptin at the intersection of neuroendocrinology and metabolism: current evidence and therapeutic perspectives. , 2013, Cell metabolism.
[12] B. Manning,et al. Signal integration by mTORC1 coordinates nutrient input with biosynthetic output , 2013, Nature Cell Biology.
[13] S. Ricoult,et al. The multifaceted role of mTORC1 in the control of lipid metabolism , 2013, EMBO reports.
[14] Yuemao Shen,et al. Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids , 2012, Nature Medicine.
[15] D. Sabatini,et al. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. , 2010, Molecular cell.
[16] N. Sonenberg,et al. S6K1 plays a critical role in early adipocyte differentiation. , 2010, Developmental cell.
[17] Shijie Li,et al. Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis , 2010, Proceedings of the National Academy of Sciences.
[18] K. Kandror,et al. Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage , 2010, Diabetes.
[19] David M. Sabatini,et al. An Emerging Role of mTOR in Lipid Biosynthesis , 2009, Current Biology.
[20] G. Kilroy,et al. High Efficiency Lipid-Based siRNA Transfection of Adipocytes in Suspension , 2009, PloS one.
[21] Chin-Lee Wu,et al. Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway , 2009, PloS one.
[22] S. Fried,et al. Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion. , 2009, American journal of physiology. Endocrinology and metabolism.
[23] M. Moskowitz,et al. Obesity Increases Vascular Senescence and Susceptibility to Ischemic Injury Through Chronic Activation of Akt and mTOR , 2009, Science Signaling.
[24] J. Friedman. Leptin at 14 y of age: an ongoing story. , 2009, The American journal of clinical nutrition.
[25] J. Auwerx,et al. Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. , 2008, Cell metabolism.
[26] B. Manning,et al. The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid. , 2008, Molecular endocrinology.
[27] Claudio R. Santos,et al. SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth , 2008, Cell metabolism.
[28] S. Fried,et al. Feeding and Insulin Increase Leptin Translation , 2007, Journal of Biological Chemistry.
[29] S. Fried,et al. Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue Published, JLR Papers in Press, May 31, 2006. , 2006, Journal of Lipid Research.
[30] A. Marette,et al. Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance. , 2005, Endocrinology.
[31] Jie Chen,et al. regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis. , 2004, Diabetes.
[32] Johan Auwerx,et al. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity , 2004, Nature.
[33] A. Tzatsos,et al. Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes. , 2003, American journal of physiology. Endocrinology and metabolism.
[34] C. Russell,et al. Regulation of the leptin content of obese human adipose tissue. , 2001, American journal of physiology. Endocrinology and metabolism.
[35] J. Auwerx,et al. Leptin , 1998, The Lancet.
[36] W. Pandak,et al. Effect of enteral versus parenteral nutrition on leptin gene expression and release into the circulation. , 1997, Biochemical and biophysical research communications.
[37] W. Yeh,et al. Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[38] J. Auwerx,et al. Transient increase in obese gene expression after food intake or insulin administration , 1995, Nature.
[39] B. Lowell,et al. Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. , 1995, The Journal of clinical investigation.
[40] M. Deitel,et al. Increased obese mRNA expression in omental fat cells from massively obese humans , 1995, Nature Medicine.
[41] M. Maffei,et al. Positional cloning of the mouse obese gene and its human homologue , 1994, Nature.
[42] K. Kandror. Translational and Post-translational Control of Leptin Production by Fat Cells , 2016 .
[43] K. Kandror,et al. The mTOR complex 1 suppresses lipolysis, stimulates lipogenesis and promotes fat storage. Running title: mTORC1 controls lipid metabolism , 2010 .