Cocaine Induces Inflammatory Gut Milieu by Compromising the Mucosal Barrier Integrity and Altering the Gut Microbiota Colonization

[1]  P. Zunino,et al.  Alterations in the Gut Microbiota of Rats Chronically Exposed to Volatilized Cocaine and Its Active Adulterants Caffeine and Phenacetin , 2018, Neurotoxicity Research.

[2]  P. Dhawan,et al.  HDAC-4 regulates claudin-2 expression in EGFR-ERK1/2 dependent manner to regulate colonic epithelial cell differentiation , 2017, Oncotarget.

[3]  Pei-Yun Tsai,et al.  IL-22 Upregulates Epithelial Claudin-2 to Drive Diarrhea and Enteric Pathogen Clearance. , 2017, Cell host & microbe.

[4]  J. Schulzke,et al.  Water channels and barriers formed by claudins , 2017, Annals of the New York Academy of Sciences.

[5]  S. Buch,et al.  HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation , 2017, The Journal of Neuroscience.

[6]  M. Neurath,et al.  Mend Your Fences , 2017, Cellular and molecular gastroenterology and hepatology.

[7]  E. Nestler,et al.  Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine , 2016, Scientific Reports.

[8]  Patrice D Cani,et al.  Human Intestinal Barrier Function in Health and Disease , 2016, Clinical and Translational Gastroenterology.

[9]  A. Nusrat,et al.  Inflammation and the Intestinal Barrier: Leukocyte-Epithelial Cell Interactions, Cell Junction Remodeling, and Mucosal Repair. , 2016, Gastroenterology.

[10]  S. Buch,et al.  Cocaine induces astrocytosis through ER stress-mediated activation of autophagy , 2016, Autophagy.

[11]  F. Bäckhed,et al.  From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites , 2016, Cell.

[12]  J. Fuhrman,et al.  Every base matters: assessing small subunit rRNA primers for marine microbiomes with mock communities, time series and global field samples. , 2016, Environmental microbiology.

[13]  C. Lebrilla,et al.  Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella. , 2016, Cell host & microbe.

[14]  Lu Yang,et al.  Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis , 2016, Journal of Neuroinflammation.

[15]  C. Weber,et al.  Claudin-2-dependent paracellular channels are dynamically gated , 2015, eLife.

[16]  J. Karn,et al.  Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR. , 2015, Virology.

[17]  B. Moore,et al.  Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients , 2015, PloS one.

[18]  Lu Yang,et al.  Cocaine-mediated microglial activation involves the ER stress-autophagy axis , 2015, Autophagy.

[19]  Mandy B. Esch,et al.  TEER Measurement Techniques for In Vitro Barrier Model Systems , 2015, Journal of laboratory automation.

[20]  T. Kosten,et al.  Emerging drugs for the treatment of cocaine use disorder: a review of neurobiological targets and pharmacotherapy , 2015, Expert opinion on emerging drugs.

[21]  M. Washington,et al.  Targeted Colonic Claudin-2 Expression Renders Resistance to Epithelial Injury, Induces Immune Suppression and Protects from Colitis , 2014, Mucosal Immunology.

[22]  Jean-Bernard Beaudry,et al.  MarvelD3 couples tight junctions to the MEKK1–JNK pathway to regulate cell behavior and survival , 2014, Journal of Cell Biology.

[23]  A. Kane,et al.  Associations of cocaine use and HIV infection with the intestinal microbiota, microbial translocation, and inflammation. , 2014, Journal of studies on alcohol and drugs.

[24]  M. Vecchi,et al.  Central Role of the Gut Epithelial Barrier in the Pathogenesis of Chronic Intestinal Inflammation: Lessons Learned from Animal Models and Human Genetics , 2013, Front. Immunol..

[25]  M. Washington,et al.  Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling , 2013, Gut.

[26]  S. Haggarty,et al.  Class I HDAC Inhibition Blocks Cocaine-Induced Plasticity Through Targeted Changes in Histone Methylation , 2013, Nature Neuroscience.

[27]  T. Cassano,et al.  Data available on the extent of cocaine use and dependence: biochemistry, pharmacologic effects and global burden of disease of cocaine abusers. , 2012, Current medicinal chemistry.

[28]  M. Washington,et al.  Caudal Homeobox Protein Cdx-2 Cooperates with Wnt Pathway to Regulate Claudin-1 Expression in Colon Cancer Cells , 2012, PloS one.

[29]  William A. Walters,et al.  Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms , 2012, The ISME Journal.

[30]  Susan Morgello,et al.  Cocaine Hijacks σ1 Receptor to Initiate Induction of Activated Leukocyte Cell Adhesion Molecule: Implication for Increased Monocyte Adhesion and Migration in the CNS , 2011, The Journal of Neuroscience.

[31]  O. Nielsen,et al.  The role of CDX2 in intestinal homeostasis and inflammation. , 2011, Biochimica et biophysica acta.

[32]  L. Turco,et al.  Caco‐2 Cells as a Model for Intestinal Absorption , 2011, Current protocols in toxicology.

[33]  H. Gendelman,et al.  Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. , 2010, Blood.

[34]  S. Milatz,et al.  Claudin-2, a component of the tight junction, forms a paracellular water channel , 2010, Journal of Cell Science.

[35]  Y. Naito,et al.  Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice , 2010, Journal of Gastroenterology.

[36]  R. DuBois,et al.  The role of COX-2 in intestinal inflammation and colorectal cancer , 2010, Oncogene.

[37]  Honghong Yao,et al.  Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways , 2009, Journal of NeuroVirology.

[38]  G. Fuchs,et al.  Massive pan-gastrointestinal bleeding following cocaine use , 2009, World journal of pediatrics : WJP.

[39]  S. Zeissig,et al.  Epithelial Tight Junctions in Intestinal Inflammation , 2009, Annals of the New York Academy of Sciences.

[40]  E. Nestler,et al.  Nuclear Factor κB Signaling Regulates Neuronal Morphology and Cocaine Reward , 2009, The Journal of Neuroscience.

[41]  Barry Press,et al.  Permeability for intestinal absorption: Caco-2 assay and related issues. , 2008, Current drug metabolism.

[42]  J. Zwiller,et al.  Histone Deacetylase Inhibitors Decrease Cocaine But Not Sucrose Self-Administration in Rats , 2008, The Journal of Neuroscience.

[43]  Tetsuya Nakamura,et al.  Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision , 2007, Journal of Gastroenterology.

[44]  B. Lhermitte,et al.  Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation , 2007, Gut.

[45]  N. Volkow,et al.  Imaging the Addicted Human Brain , 2007, Science & practice perspectives.

[46]  U Wahnschaffe,et al.  Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease , 2006, Gut.

[47]  E. Nestler The Neurobiology of Cocaine Addiction , 2005, Science & practice perspectives.

[48]  M. Kreek,et al.  Conditioned place preference after single doses or “binge” cocaine in C57BL/6J and 129/J mice , 2002, Pharmacology Biochemistry and Behavior.

[49]  D. Goodenough,et al.  Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells. , 2000, Molecular biology of the cell.

[50]  Y. Berger,et al.  The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications , 1995, Cell Biology and Toxicology.

[51]  L. Cregler,et al.  Medical complications of cocaine abuse. , 1986, The New England journal of medicine.

[52]  H. Nalbandian,et al.  Intestinal ischemia caused by cocaine ingestion: report of two cases. , 1985, Surgery.

[53]  S. Beebe,et al.  Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-κB in transiently cotransfected heart cells , 2007, Cardiovascular Toxicology.

[54]  A. Stammati,et al.  The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics , 2005, Cell Biology and Toxicology.

[55]  Yuan Wang,et al.  Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells. , 2004, Experimental eye research.

[56]  John H. Jopson,et al.  A REPORT OF TWO CASES , 1902 .