Profiling of Ubiquitin-like Modifications Reveals Features of Mitotic Control

[1]  T. Johansen,et al.  The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation , 2012, Journal of Cell Science.

[2]  J. Casanova,et al.  Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency , 2012, Science.

[3]  A. Ciechanover,et al.  FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination , 2012, Molecular biology of the cell.

[4]  S. Gygi,et al.  Alternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins. , 2011, Molecular cell.

[5]  Xin-Yun Huang,et al.  SUMOylation-regulated Protein Phosphorylation, Evidence from Quantitative Phosphoproteomics Analyses* , 2011, The Journal of Biological Chemistry.

[6]  T. Urano,et al.  Mitotic kinase Aurora‐B is regulated by SUMO‐2/3 conjugation/deconjugation during mitosis , 2011, Genes to cells : devoted to molecular & cellular mechanisms.

[7]  P. B. Chock,et al.  FAT10 modifies p53 and upregulates its transcriptional activity. , 2011, Archives of biochemistry and biophysics.

[8]  S. French,et al.  Increased expression of FAT10 in colon benign, premalignant and malignant epithelial neoplasms. , 2011, Experimental and molecular pathology.

[9]  M. Malumbres,et al.  SUMOylation modulates the function of Aurora-B kinase , 2010, Journal of Cell Science.

[10]  J. Huibregtse,et al.  The ISG15 Conjugation System Broadly Targets Newly Synthesized Proteins: Implications for the Antiviral Function of ISG15 , 2010, Molecular Cell.

[11]  P. Sheppard,et al.  USE1 is a bispecific conjugating enzyme for ubiquitin and FAT10, which FAT10ylates itself in cis. , 2010, Nature communications.

[12]  R. Durbin,et al.  Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes , 2010, Nature.

[13]  O. Larsson,et al.  SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor , 2010, Science Signaling.

[14]  P. Klotman,et al.  FAT10: a Novel Mediator of Vpr-Induced Apoptosis in Human Immunodeficiency Virus-Associated Nephropathy , 2009, Journal of Virology.

[15]  G. Barton,et al.  System-Wide Changes to SUMO Modifications in Response to Heat Shock , 2009, Science Signaling.

[16]  M. Hochstrasser,et al.  Origin and function of ubiquitin-like proteins , 2009, Nature.

[17]  M. Roussel,et al.  E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. , 2009, Molecular cell.

[18]  Marc W Kirschner,et al.  Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays , 2009, Proceedings of the National Academy of Sciences.

[19]  B. Kessler,et al.  Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles , 2008, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

[20]  Karl Mechtler,et al.  BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals , 2008, Nature Methods.

[21]  M. Tyers,et al.  Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation. , 2008, Molecular cell.

[22]  M. Mann,et al.  In Vivo Identification of Human Small Ubiquitin-like Modifier Polymerization Sites by High Accuracy Mass Spectrometry and an in Vitro to in Vivo Strategy*S , 2008, Molecular & Cellular Proteomics.

[23]  S. Gygi,et al.  Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging , 2007, Nature.

[24]  H. Yoo,et al.  Identification of novel regulators of apoptosis using a high-throughput cell-based screen. , 2007, Molecules and cells.

[25]  M. Kirschner,et al.  Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation , 2007, Nature.

[26]  Jeffrey T Leek,et al.  The optimal discovery procedure for large-scale significance testing, with applications to comparative microarray experiments. , 2007, Biostatistics.

[27]  Dong-er Zhang,et al.  ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP. , 2007, Genes & development.

[28]  Daniela Hoeller,et al.  Ubiquitin and ubiquitin-like proteins in cancer pathogenesis , 2006, Nature Reviews Cancer.

[29]  S. Weissman,et al.  FAT10/Diubiquitin-Like Protein-Deficient Mice Exhibit Minimal Phenotypic Differences , 2006, Molecular and Cellular Biology.

[30]  Siew Hong Leong,et al.  FAT10 Plays a Role in the Regulation of Chromosomal Stability* , 2006, Journal of Biological Chemistry.

[31]  K. Jeang,et al.  p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers , 2006, Oncogene.

[32]  V. D’Agati,et al.  Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. , 2006, Journal of the American Society of Nephrology : JASN.

[33]  R. Brasseur,et al.  Exclusive Ubiquitination and Sumoylation on Overlapping Lysine Residues Mediate NF-κB Activation by the Human T-Cell Leukemia VirusTax Oncoprotein , 2005, Molecular and Cellular Biology.

[34]  G. Gill,et al.  Something about SUMO inhibits transcription. , 2005, Current opinion in genetics & development.

[35]  H. Murakami,et al.  Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner. , 2005, Pigment cell research.

[36]  Efterpi Papouli,et al.  Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. , 2005, Molecular cell.

[37]  M. Hipp,et al.  FAT10, a Ubiquitin-Independent Signal for Proteasomal Degradation , 2005, Molecular and Cellular Biology.

[38]  Hongtao Yu,et al.  Systematic Identification and Analysis of Mammalian Small Ubiquitin-like Modifier Substrates* , 2005, Journal of Biological Chemistry.

[39]  Marc W. Kirschner,et al.  Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry , 2004, Nature.

[40]  N. Hattori,et al.  Pathogenetic mechanisms of parkin in Parkinson's disease , 2004, The Lancet.

[41]  M. Tatham,et al.  SUMO and transcriptional regulation. , 2004, Seminars in cell & developmental biology.

[42]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[43]  O. Larsson,et al.  Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[44]  M. Choti,et al.  Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers , 2003, Oncogene.

[45]  Terence P. Speed,et al.  A comparison of normalization methods for high density oligonucleotide array data based on variance and bias , 2003, Bioinform..

[46]  Sridhar Ramaswamy,et al.  Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability , 2002, Cell.

[47]  Y. Benjamini,et al.  Controlling the false discovery rate in behavior genetics research , 2001, Behavioural Brain Research.

[48]  M. Groettrup,et al.  The Ubiquitin-like Protein FAT10 Forms Covalent Conjugates and Induces Apoptosis* , 2001, The Journal of Biological Chemistry.

[49]  R. Honda,et al.  Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1). , 2000, Biochemical and biophysical research communications.

[50]  Michele Pagano,et al.  SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 , 1999, Nature Cell Biology.

[51]  P. Howley,et al.  Identification of HHR23A as a Substrate for E6-associated Protein-mediated Ubiquitination* , 1999, The Journal of Biological Chemistry.

[52]  S. Weissman,et al.  A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[53]  M. Groettrup,et al.  FAT10 : Activated by UBA6 and Functioning in Protein Degradation. , 2010, Sub-cellular biochemistry.

[54]  T. Hunter,et al.  Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. , 2007, Nature Reviews Molecular Cell Biology.

[55]  A. Sharrocks,et al.  Interplay of the SUMO and MAP kinase pathways. , 2006, Ernst Schering Research Foundation workshop.

[56]  Anushya Muruganujan,et al.  PANTHER: a browsable database of gene products organized by biological function, using curated protein family and subfamily classification , 2003, Nucleic Acids Res..