Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes.
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D. Strachan | J. Todd | N. Walker | Richard W Jones | W. McArdle | S. Ring | L. Maier | J. Howson | Rebecca Bailey | F. Payne | C. Lowe | G. Spickett
[1] Wendy Thomson,et al. Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene. , 2005, Arthritis and rheumatism.
[2] Adrian Vella,et al. Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. , 2005, American journal of human genetics.
[3] D. Vercelli,et al. IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation. , 2005, The Journal of clinical investigation.
[4] Juliet M Chapman,et al. No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes. , 2005, American journal of human genetics.
[5] D. Clayton,et al. Genome-wide association studies: theoretical and practical concerns , 2005, Nature Reviews Genetics.
[6] S. Weiland,et al. A Comprehensive Analysis of Interleukin-4 Receptor Polymorphisms and Their Association with Atopy and IgE Regulation in Childhood , 2004, International Archives of Allergy and Immunology.
[7] M. Wills-Karp,et al. Interleukin‐13 in asthma pathogenesis , 2004, Immunological reviews.
[8] I. James,et al. Alleles of the IL12B 3'UTR associate with late onset of type 1 diabetes. , 2004, Human immunology.
[9] Adrian Vella,et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. , 2004, Diabetes.
[10] E. Silverman,et al. The IL12B gene is associated with asthma. , 2004, American journal of human genetics.
[11] G. K. Khurana Hershey,et al. Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants. , 2004, The Journal of allergy and clinical immunology.
[12] B. Lie,et al. CTLA-4 polymorphisms in allergy and asthma and the TH1/ TH2 paradigm. , 2004, The Journal of allergy and clinical immunology.
[13] Steven J. Schrodi,et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. , 2004, American journal of human genetics.
[14] Javier Martín,et al. Association of the CT60 marker of the CTLA4 gene with systemic lupus erythematosus. , 2004, Arthritis and rheumatism.
[15] S. Szabo,et al. Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities. , 2004, The Journal of allergy and clinical immunology.
[16] F. Pociot,et al. Genetic and functional evaluation of an interleukin-12 polymorphism (IDDM18) in families with type 1 diabetes , 2004, Journal of Medical Genetics.
[17] D. Clayton,et al. Betting odds and genetic associations. , 2004, Journal of the National Cancer Institute.
[18] Nunzio Bottini,et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes , 2004, Nature Genetics.
[19] D. Nicolae,et al. Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy. , 2004, The Journal of allergy and clinical immunology.
[20] J. Goldblatt,et al. Associations of the IL12B promoter polymorphism in longitudinal data from asthmatic patients 7 to 42 years of age. , 2004, The Journal of allergy and clinical immunology.
[21] Juliet M Chapman,et al. Detecting Disease Associations due to Linkage Disequilibrium Using Haplotype Tags: A Class of Tests and the Determinants of Statistical Power , 2003, Human Heredity.
[22] H. Malling,et al. Association between an interleukin-13 promoter polymorphism and atopy. , 2003, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.
[23] C. Cardwell,et al. A meta-analysis of the association between childhood type 1 diabetes and atopic disease. , 2003, Diabetes care.
[24] Chao Lu,et al. A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis , 2003, Human Genetics.
[25] T. Beaty,et al. Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study. , 2003, The Journal of allergy and clinical immunology.
[26] M. Chan-yeung,et al. Genetic variants of the IL13 and IL4 genes and atopic diseases in at-risk children , 2003, Genes and Immunity.
[27] A. Rao,et al. An epigenetic view of helper T cell differentiation , 2003, Nature Immunology.
[28] Luc J. Smink,et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease , 2003, Nature.
[29] P. McKeigue,et al. Problems of reporting genetic associations with complex outcomes , 2003, The Lancet.
[30] Thomas A Trikalinos,et al. Genetic associations in large versus small studies: an empirical assessment , 2003, The Lancet.
[31] E. Lander,et al. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease , 2003, Nature Genetics.
[32] D. Postma,et al. Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28. , 2002, The Journal of allergy and clinical immunology.
[33] D. Middleton,et al. The IL12B 3′ untranslated region DNA polymorphism is not associated with early-onset type 1 diabetes , 2002, Genes and Immunity.
[34] G. Morahan,et al. Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children , 2002, The Lancet.
[35] J. She,et al. IL-12p40 is associated with type 1 diabetes in Caucasian-American families. , 2002, Diabetes.
[36] R. Puri,et al. Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma. , 2002, The Journal of allergy and clinical immunology.
[37] L. Nisticò,et al. IL12B polymorphism and type 1 diabetes in the Italian population: a case-control study. , 2002, Diabetes.
[38] J. Hirschhorn,et al. A comprehensive review of genetic association studies , 2002, Genetics in Medicine.
[39] E. Silverman,et al. Lack of association between a polymorphism in the interleukin‐13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica , 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[40] John A. Todd,et al. Parameters for reliable results in genetic association studies in common disease , 2002, Nature Genetics.
[41] T. Spector,et al. Concordance and interrelationship of atopic diseases and markers of allergic sensitization among adult female twins. , 2001, The Journal of allergy and clinical immunology.
[42] David Clayton,et al. Epidemiological methods for studying genes and environmental factors in complex diseases , 2001, The Lancet.
[43] D. Postma,et al. Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. , 2001, American journal of respiratory cell and molecular biology.
[44] J. Todd,et al. Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models. , 2001, Immunity.
[45] Y. Matsuzawa,et al. Pancreatic biopsy as a procedure for detecting in situ autoimmune phenomena in type 1 diabetes: close correlation between serological markers and histological evidence of cellular autoimmunity. , 2001, Diabetes.
[46] K. Deichmann,et al. A novel polymorphism in the 5′ promoter region of the human interleukin-4 receptor α-chain gene is associated with decreased soluble interleukin-4 receptor protein levels , 2001, Immunogenetics.
[47] G. Morahan,et al. Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele , 2001, Nature Genetics.
[48] K. Chung,et al. Allergen-Specific Th1 Cells Counteract Efferent Th2 Cell-Dependent Bronchial Hyperresponsiveness and Eosinophilic Inflammation Partly Via IFN-γ1 , 2001, The Journal of Immunology.
[49] K. Deichmann,et al. Genetic variants of IL-13 signalling and human asthma and atopy. , 2000, Human molecular genetics.
[50] S. Weiland,et al. A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children. , 2000, The Journal of allergy and clinical immunology.
[51] A. Tsalenko,et al. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. , 2000, American journal of human genetics.
[52] S. Holgate. The epidemic of allergy and asthma , 1999, Nature.
[53] E. Groot,et al. An IL-13 promoter polymorphism associated with increased risk of allergic asthma , 1999, Genes and Immunity.
[54] S. Stevens,et al. Interferon-gamma therapy reduces blood leukocyte levels in patients with atopic dermatitis: correlation with clinical improvement. , 1999, Clinical immunology.
[55] D. Strachan. The epidemiology of childhood asthma , 1999, Allergy.
[56] Williams,et al. The natural history of childhood eczema: observations from the British 1958 birth cohort study , 1998, The British journal of dermatology.
[57] T. Chatila,et al. The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor. , 1997, The New England journal of medicine.
[58] H. Nolte,et al. Performance characteristics of a new automated enzyme immunoassay for the measurement of allergen-specific IgE. Summary of the probability outcomes comparing results of allergen skin testing to results obtained with the HYTEC system and CAP system. , 1997, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[59] T. Shirakawa,et al. Association between atopic asthma and a coding variant of Fc epsilon RI beta in a Japanese population. , 1996, Human molecular genetics.
[60] D. Strachan,et al. Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort , 1996, BMJ.
[61] A. James,et al. Fc(epsilon)RI-(beta) polymorphism and risk of atopy in a general population sample , 1995, BMJ.
[62] D. Strachan,et al. Childhood eczema: disease of the advantaged? , 1994, BMJ.
[63] D. Pipeleers,et al. Pancreatic beta cells in insulin-dependent diabetes. , 1992, Diabetes/metabolism reviews.
[64] D. P. Strachan,et al. Hay fever, hygiene, and household size. , 1989, BMJ.
[65] R. Townley,et al. Genetic analysis of allergic disease in twins. , 1984, The Journal of allergy and clinical immunology.
[66] R. Hubbard,et al. There is no evidence of an inverse relationship between TH2-mediated atopy and TH1-mediated autoimmune disorders: Lack of support for the hygiene hypothesis. , 2003, The Journal of allergy and clinical immunology.
[67] D. Clayton,et al. A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes. , 2002, American journal of human genetics.
[68] S. Constant,et al. Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches. , 1997, Annual review of immunology.