Biosynthesis of streptothricin antibiotics. III. Incorporation of D-glucosamine into D-gulosamine moiety of racemomycin-A.

When D-glucosamine-1-14C was added to a growing culture of Streptomyces lavendulae ISP-5069, a high incorporation of radioactivity into racemomycin-A was observed. Radioactivity was exclusively located in D-gulosamine moiety of the molecule.