Intravenous Transplantation of Human Umbilical Cord Blood Mononuclear Cells Overexpressing Nerve Growth Factor Improves Spatial Memory in APP/PS1 Transgenic Mice with a Model of Alzheimer’s Disease

[1]  A. Palotás,et al.  Tandem Delivery of Multiple Therapeutic Genes Using Umbilical Cord Blood Cells Improves Symptomatic Outcomes in ALS , 2017, Molecular Neurobiology.

[2]  Eric Westman,et al.  Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease , 2015, Alzheimer's & Dementia.

[3]  A. Palotás,et al.  Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule. , 2015, Current gene therapy.

[4]  R. Pallini,et al.  Human Olfactory Bulb Neural Stem Cells expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model , 2015, Journal of cellular physiology.

[5]  A. Cuello,et al.  Nerve growth factor metabolic dysfunction in Alzheimer's disease and Down syndrome. , 2014, Trends in pharmacological sciences.

[6]  H. Bobby Gaspar,et al.  Hematopoietic SCT in Europe: data and trends in 2011 , 2013, Bone Marrow Transplantation.

[7]  V. V. Solovieva,et al.  Analysis of the Efficiency of Gene-Cell Therapy in Transgenic Mice with Amyotrophic Lateral Sclerosis Phenotype , 2013, Bulletin of Experimental Biology and Medicine.

[8]  A. Zefirov,et al.  [The influence of beta-amyloid peptide on the functions of excitable tissues: physiological and pathological aspects]. , 2013, Uspekhi fiziologicheskikh nauk.

[9]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[10]  A. Cattaneo,et al.  Transgenic Mice with Chronic NGF Deprivation and Alzheimer's Disease-Like Pathology Display Hippocampal Region-Specific Impairments in Short- and Long-Term Plasticities , 2010, The Journal of Neuroscience.

[11]  Min Zhang,et al.  Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions , 2010, Journal of Translational Medicine.

[12]  T. Sejnowski,et al.  NGF Is Essential for Hippocampal Plasticity and Learning , 2009, The Journal of Neuroscience.

[13]  S. Capsoni,et al.  Development of a non invasive NGF-based therapy for Alzheimer's disease. , 2009, Current Alzheimer research.

[14]  M. Tuszynski,et al.  Therapeutic potential of CERE-110 (AAV2-NGF): Targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons , 2008, Experimental Neurology.

[15]  D. Harris,et al.  Umbilical cord blood: a unique source of pluripotent stem cells for regenerative medicine. , 2007, Current stem cell research & therapy.

[16]  R. Dermietzel,et al.  Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro. , 2007, Experimental hematology.

[17]  M. Tuszynski,et al.  Nerve Growth Factor Gene Therapy in Alzheimer Disease , 2007, Alzheimer disease and associated disorders.

[18]  B. Melchior,et al.  CNS immune privilege: hiding in plain sight , 2006, Immunological reviews.

[19]  Sophie Pezet,et al.  Neurotrophins: mediators and modulators of pain. , 2006, Annual review of neuroscience.

[20]  J. Rawlins,et al.  T-maze alternation in the rodent , 2006, Nature Protocols.

[21]  A. Cattaneo,et al.  Time window in cholinomimetic ability to rescue long-term potentiation in neurodegenerating anti-nerve growth factor mice. , 2006, Journal of Alzheimer's disease : JAD.

[22]  Z. Han,et al.  Human umbilical cord blood cells express neurotrophic factors , 2005, Neuroscience Letters.

[23]  Steven G Potkin,et al.  A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease , 2005, Nature Medicine.

[24]  E. Ekestern Neurotrophic Factors and Amyotrophic Lateral Sclerosis , 2004, Neurodegenerative Diseases.

[25]  D. Swaab,et al.  Alzheimer’s disease and NGF signaling , 2004, Journal of Neural Transmission.

[26]  T. Hawley,et al.  Multiparameter flow cytometry of fluorescent protein reporters. , 2004, Methods in molecular biology.

[27]  P. Sanberg,et al.  Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. , 2003, Journal of hematotherapy & stem cell research.

[28]  A. Cattaneo,et al.  β-Amyloid Plaques in a Model for Sporadic Alzheimer's Disease Based on Transgenic Anti-Nerve Growth Factor Antibodies , 2002, Molecular and Cellular Neuroscience.

[29]  E. Huang,et al.  Neurotrophins: roles in neuronal development and function. , 2001, Annual review of neuroscience.

[30]  E. Alleva,et al.  NGF expression in the developing rat brain: effects of maternal separation. , 2000, Brain research. Developmental brain research.

[31]  W. Galpern,et al.  NGF attenuates 3-nitrotyrosine formation in a 3-NP model of Huntington's disease. , 1996, Neuroreport.

[32]  W. Mcbride,et al.  Performance in the cross‐maze and slip funnel tests of four pairs of rat lines selectively bred for divergent alcohol drinking behavior , 1996, Addiction biology.

[33]  R. Macias,et al.  NGF in experimental models of parkinson disease , 1996, Molecular and chemical neuropathology.

[34]  E. Shooter,et al.  Nerve growth factor in neuronal development and maintenance. , 1987, The Journal of experimental biology.

[35]  F. Gage,et al.  Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[36]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.