Anti-proliferative and anti-inflammatory effects of 3β,6β,16β-Trihydroxylup-20(29)-ene on cutaneous inflammation.

[1]  E. Teixeira,et al.  Effect of the triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene isolated from the leaves of Combretum leprosum Mart. on cutaneous wounds in mice. , 2015, Journal of ethnopharmacology.

[2]  L. Moreira-Dill,et al.  A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro , 2015, BMC Complementary and Alternative Medicine.

[3]  J. Putney,et al.  Role of the store‐operated calcium entry protein, STIM1, in neutrophil chemotaxis and infiltration into a murine model of psoriasis‐inflamed skin , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  A. Harvey,et al.  The re-emergence of natural products for drug discovery in the genomics era , 2015, Nature Reviews Drug Discovery.

[5]  W. Bollag,et al.  The Antipsoriatic Agent Monomethylfumarate Has Antiproliferative, Prodifferentiative, and Anti-Inflammatory Effects on Keratinocytes , 2015, The Journal of Pharmacology and Experimental Therapeutics.

[6]  Robert J G Chalmers,et al.  Assessing psoriasis severity and outcomes for clinical trials and routine clinical practice. , 2015, Dermatologic clinics.

[7]  D. Moura,et al.  The natural triterpene 3β,6β,16β-trihydroxy-lup-20(29)-ene obtained from the flowers of Combretum leprosum induces apoptosis in MCF-7 breast cancer cells , 2014, BMC Complementary and Alternative Medicine.

[8]  E. Teixeira,et al.  Antimicrobial Effect of the Triterpene 3β,6β,16β-Trihydroxylup-20(29)-ene on Planktonic Cells and Biofilms from Gram Positive and Gram Negative Bacteria , 2014, BioMed research international.

[9]  N. Moorchung,et al.  A Study of Various Histopathological Features and their Relevance in Pathogenesis of Psoriasis , 2013, Indian journal of dermatology.

[10]  M. Otuki,et al.  Combretum leprosum Mart. (Combretaceae): potential as an antiproliferative and anti-inflammatory agent. , 2013, Journal of ethnopharmacology.

[11]  P. Filipe,et al.  Mechanisms of Action of Topical Corticosteroids in Psoriasis , 2012, International journal of endocrinology.

[12]  C. Baggio,et al.  Anti-inflammatory effect of triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene obtained from Combretum leprosum Mart & Eich in mice. , 2012, Journal of ethnopharmacology.

[13]  Xin Li,et al.  Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis , 2011, Evidence-based complementary and alternative medicine : eCAM.

[14]  Z. Zuo,et al.  Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity. , 2011, European journal of pharmacology.

[15]  A. Kimball,et al.  Latitude and psoriasis prevalence. , 2011, Journal of the American Academy of Dermatology.

[16]  J. Zuliani,et al.  Activity of the Lupane isolated from Combretum leprosum against Leishmania amazonensis promastigotes , 2011 .

[17]  D. Martins,et al.  Further analyses of mechanisms underlying the antinociceptive effect of the triterpene 3β, 6β, 16β-trihydroxylup-20(29)-ene in mice. , 2011, European journal of pharmacology.

[18]  D. Martins,et al.  Spinal antinociception evoked by the triterpene 3beta, 6beta, 16beta-trihydroxylup-20(29)-ene in mice: evidence for the involvement of the glutamatergic system via NMDA and metabotropic glutamate receptors. , 2009, European journal of pharmacology.

[19]  G. Krueger,et al.  Observations of psoriasis in the absence of therapeutic intervention identifies two unappreciated morphologic variants, thin-plaque and thick-plaque psoriasis, and their associated phenotypes. , 2006, The Journal of investigative dermatology.

[20]  C. Glass,et al.  Nuclear receptors versus inflammation: mechanisms of transrepression , 2006, Trends in Endocrinology & Metabolism.

[21]  I. Boehm.  Apoptosis in physiological and pathological skin: implications for therapy. , 2006, Current molecular medicine.

[22]  Yoshitaka Tanaka,et al.  Involvement of tumor necrosis factor (TNF)-alpha in phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin edema in mice. , 2006, Biochemical pharmacology.

[23]  A. Santos,et al.  Antinociceptive properties of the ethanolic extract and of the triterpene 3β,6β,16β-trihidroxilup-20(29)-ene obtained from the flowers of Combretum leprosum in mice , 2006, Pharmacology Biochemistry and Behavior.

[24]  A. Santos,et al.  Antinociceptive properties of the ethanolic extract and of the triterpene 3beta,6beta,16beta-trihidroxilup-20(29)-ene obtained from the flowers of Combretum leprosum in mice. , 2006, Pharmacology, biochemistry, and behavior.

[25]  Christopher K. Glass,et al.  Combinatorial roles of nuclear receptors in inflammation and immunity , 2006, Nature Reviews Immunology.

[26]  R. Schwartz,et al.  Adverse effects of topical glucocorticosteroids. , 2006, Journal of the American Academy of Dermatology.

[27]  R. Yunes,et al.  Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene. , 2005, European journal of pharmacology.

[28]  E. Bernardis,et al.  Protective effects of papaverine salicylate in mouse ear dermatitis and PAF-induced rat paw oedema , 1994, Agents and Actions.

[29]  P. Stanley,et al.  Temporal infiltration of leukocyte subsets into mouse skin inflamed with phorbol ester , 1992, Agents and Actions.

[30]  J. Young,et al.  Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents , 1989, Agents and Actions.

[31]  A. Gottlieb.  Psoriasis: emerging therapeutic strategies , 2005, Nature Reviews Drug Discovery.

[32]  David J Margolis,et al.  Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. , 2004, The journal of investigative dermatology. Symposium proceedings.

[33]  K. Asadullah,et al.  Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[34]  G. Weinstein,et al.  Psoriasis: current perspectives with an emphasis on treatment. , 1999, The American journal of medicine.

[35]  J. J. Moreno,et al.  Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin. , 1999, Biochemical pharmacology.

[36]  R. Gniadecki.  Regulation of keratinocyte proliferation. , 1998, General pharmacology.

[37]  R. Braz-Filho,et al.  Triterpenes and flavonoids from Combretum leprosum , 1993 .

[38]  P. Stanley,et al.  Mouse skin inflammation induced by multiple topical applications of 12-O-tetradecanoylphorbol-13-acetate. , 1991, Skin pharmacology : the official journal of the Skin Pharmacology Society.

[39]  D. Priebat,et al.  Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. , 1982, The Journal of investigative dermatology.