Laryngeal spindle cell carcinoma: A population‐based analysis of incidence and survival

Laryngeal spindle cell carcinoma (LSpCC) is a rare variant of squamous cell carcinoma. Surgery is the reported mainstay of treatment, but previous analyses failed to demonstrate survival outcomes by therapeutic modality. This study aims to carry out the largest population‐based analysis of this histology to determine tumor characteristics, incidence, survival, and prognostic indicators.

[1]  M. Xiao,et al.  Clinicopathological and immunohistochemical analysis of spindle cell carcinoma of the larynx or hypopharynx: A report of three cases , 2014, Oncology letters.

[2]  R. Seethala,et al.  Spindle Cell Carcinoma of the Larynx with Rhabdomyoblastic Heterologous Element: A Rare Form of Divergent Differentiation , 2013, Head and Neck Pathology.

[3]  S. El-Mofty,et al.  Spindle Cell Carcinomas of the Head and Neck Rarely Harbor Transcriptionally-Active Human Papillomavirus , 2013, Head and Neck Pathology.

[4]  C. Bradford,et al.  Clinical and Pathologic Predictors of Recurrence and Survival in Spindle Cell Squamous Cell Carcinoma , 2011, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[5]  L. Thompson Laryngeal Spindle Cell Squamous Cell Carcinoma , 2011, Ear, nose, & throat journal.

[6]  G. Altavilla,et al.  Spindle-cell Tumours of the Larynx: Diagnostic Pitfalls. A Case Report and Review of the Literature , 2003, Acta oto-laryngologica.

[7]  L. Thompson,et al.  Spindle Cell (Sarcomatoid) Carcinomas of the Larynx: A Clinicopathologic Study of 187 Cases , 2002, The American journal of surgical pathology.

[8]  A. Garden,et al.  Radiation Therapy for Early Stage (T1‐T2) Sarcomatoid Carcinoma of True Vocal Cords: Outcomes and Patterns of Failure , 1998, The Laryngoscope.

[9]  T. Sebo,et al.  Spindle cell carcinoma of the larynx: review of 26 cases including DNA content and immunohistochemistry. , 1997, Human pathology.

[10]  B. Hainau,et al.  Spindle cell carcinoma of the larynx. , 1984, Acta oto-laryngologica.

[11]  G. Brodsky,et al.  Carcino(pseudo)sarcoma of the larynx: the controversy continues. , 1984, Otolaryngologic clinics of North America.

[12]  J. Batsakis,et al.  ‘Pseudosarcoma’ of the mucous membranes in the head and neck , 1981, The Journal of Laryngology & Otology.

[13]  G. Berci,et al.  Pseudosarcoma of the larynx: a comprehensive analysis. , 1980, Archives of otolaryngology.

[14]  M. Maurizi [Sarcoma of the larynx]. , 1961, Annali di laringologia, otologia, rinologia, faringologia.