ONTOLOGY BASED DESIGN FOR INTEGRATIVE SIMULATION OF HUMAN PHYSIOLOGY

Mathematical modeling of physiological processes of human bodyhas been studiedin all levels fromcell up to organs and organ systems. Although the initial idea for working on individual models of human physiology was to have a better understanding of the whole mechanism, not enough integrative approaches have been developed yet. To build an integrative framework for physiological processes, the first step should be defining anatomical structure of human body. For the integration of the mathematical models, which represent physiological processes at different levels, horizontal and vertical connectionof the anatomical structure is required. In this paper we present the high level design of an application programming interface, which aims to provide integration of multilevel physiological models through an ontology based framework.

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