The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin.

[1]  R. Burgeson,et al.  Characterization and Expression of the Laminin γ3 Chain: A Novel, Non-Basement Membrane–associated, Laminin Chain , 1999, The Journal of cell biology.

[2]  T. Sasaki,et al.  Analysis of heparin, alpha-dystroglycan and sulfatide binding to the G domain of the laminin alpha1 chain by site-directed mutagenesis. , 1999, Journal of molecular biology.

[3]  R. Timpl,et al.  Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α‐dystroglycan and several extracellular matrix proteins , 1999 .

[4]  K. Campbell,et al.  Role of α-Dystroglycan as a Schwann Cell Receptor for Mycobacterium leprae , 1998 .

[5]  K. Campbell,et al.  A Role for Dystroglycan in Basement Membrane Assembly , 1998, Cell.

[6]  T. Südhof,et al.  The Making of Neurexins , 1998, Journal of neurochemistry.

[7]  K. Campbell,et al.  Dystroglycan in development and disease. , 1998, Current opinion in cell biology.

[8]  N. Smyth,et al.  The role of laminins in basement membrane function , 1998, Journal of anatomy.

[9]  R. Timpl,et al.  Structural analysis and proteolytic processing of recombinant G domain of mouse laminin α2 chain , 1998 .

[10]  P. Bork,et al.  Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxins. , 1998, Journal of molecular biology.

[11]  R. Kammerer,et al.  Electron microscopic structure of agrin and mapping of its binding site in laminin‐1 , 1998, The EMBO journal.

[12]  M. Ruegg,et al.  Agrin Is a High-affinity Binding Protein of Dystroglycan in Non-muscle Tissue* , 1998, The Journal of Biological Chemistry.

[13]  J. Ervasti,et al.  Tissue-specific Heterogeneity in α-Dystroglycan Sialoglycosylation , 1997, The Journal of Biological Chemistry.

[14]  M. Ruegg,et al.  Agrin Binds to the Nerve–Muscle Basal Lamina via Laminin , 1997, The Journal of cell biology.

[15]  R M Esnouf,et al.  An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. , 1997, Journal of molecular graphics & modelling.

[16]  I. Kanazawa,et al.  Structures of Sialylated O-Linked Oligosaccharides of Bovine Peripheral Nerve α-Dystroglycan , 1997, The Journal of Biological Chemistry.

[17]  M. Ruegg,et al.  Dystroglycan Is a Dual Receptor for Agrin and Laminin-2 in Schwann Cell Membrane* , 1996, The Journal of Biological Chemistry.

[18]  J. Fallon,et al.  Alternative splicing of agrin regulates its binding to heparin alpha-dystroglycan, and the cell surface. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[19]  R. Scheller,et al.  Alternative RNA splicing that determines agrin activity regulates binding to heparin and alpha-dystroglycan. , 1996, Development.

[20]  I. Kanazawa,et al.  Characterization of Dystroglycan‐Laminin Interaction in Peripheral Nerve , 1996, Journal of neurochemistry.

[21]  M. Ruegg,et al.  Alternative Splicing of Agrin Alters Its Binding to Heparin, Dystroglycan, and the Putative Agrin Receptor , 1996, Neuron.

[22]  W. Hoch,et al.  Agrin binding to alpha-dystroglycan. Domains of agrin necessary to induce acetylcholine receptor clustering are overlapping but not identical to the alpha-dystroglycan-binding region. , 1996, The Journal of biological chemistry.

[23]  J. Ervasti,et al.  Differential Heparin Inhibition of Skeletal Muscle -Dystroglycan Binding to Laminins (*) , 1996, The Journal of Biological Chemistry.

[24]  R. Timpl,et al.  Supramolecular assembly of basement membranes , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[25]  A. Utani,et al.  Identification of Cell Binding Sites in the Laminin α1 Chain Carboxyl-terminal Globular Domain by Systematic Screening of Synthetic Peptides (*) , 1995, The Journal of Biological Chemistry.

[26]  J. Engel,et al.  Electron microscopic evidence for a mucin‐like region in chick muscle α‐dystroglycan , 1995 .

[27]  N. Smalheiser,et al.  Purification of Cranin, a Laminin Binding Membrane Protein , 1995, The Journal of Biological Chemistry.

[28]  K. Campbell.  Three muscular dystrophies: Loss of cytoskeleton-extracellular matrix linkage , 1995, Cell.

[29]  R. Liddington,et al.  Crystal structure of the A domain from the a subunit of integrin CR3 (CD11 b/CD18) , 1995, Cell.

[30]  E A Merritt,et al.  Raster3D Version 2.0. A program for photorealistic molecular graphics. , 1994, Acta crystallographica. Section D, Biological crystallography.

[31]  K. Campbell,et al.  Dystroglycan is a binding protein of laminin and merosin in peripheral nerve , 1994, FEBS letters.

[32]  Collaborative Computational,et al.  The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.

[33]  C. Sander,et al.  The FSSP database of structurally aligned protein fold families. , 1994, Nucleic acids research.

[34]  Z. Hall,et al.  Dystroglycan binds nerve and muscle agrin , 1994, Neuron.

[35]  S. Carbonetto,et al.  Dystroglycan-α, a dystrophin-associated glycoprotein, is a functional agrin receptor , 1994, Cell.

[36]  K. Campbell,et al.  A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering , 1994, Cell.

[37]  J. Leszyk,et al.  Identification and purification of an agrin receptor from torpedo postsynaptic membranes: A heteromeric complex related to the dystroglycans , 1994, Neuron.

[38]  T. Blundell,et al.  Structure of pentameric human serum amyloid P component , 1994, Nature.

[39]  G. Kleywegt,et al.  Halloween ... Masks and Bones , 1994 .

[40]  N. Smalheiser.  Cranin interacts specifically with the sulfatide‐binding domain of laminin , 1993, Journal of neuroscience research.

[41]  P. Yurchenco,et al.  Cell and heparin binding in the distal long arm of laminin: identification of active and cryptic sites with recombinant and hybrid glycoprotein [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1623] , 1993, The Journal of cell biology.

[42]  P. Yurchenco,et al.  Self-assembly and calcium-binding sites in laminin. A three-arm interaction model. , 1993, The Journal of biological chemistry.

[43]  J. Ervasti,et al.  A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin , 1993, The Journal of cell biology.

[44]  S. Carbonetto,et al.  Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparin binding domain of laminin. , 1993, The Journal of biological chemistry.

[45]  K. Drickamer.  Ca2+-dependent carbohydrate-recognition domains in animal proteins , 1993 .

[46]  J. Engel.  8 – Structure and Function of Laminin , 1993 .

[47]  M. Baker,et al.  Sex hormone‐binding globulin, androgen‐binding protein, and vitamin K‐dependent protein S are homologous to laminin A, merosin, and Drosophila crumbs protein , 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[48]  K. Sharp,et al.  Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons , 1991, Proteins.

[49]  P. Kraulis.  A program to produce both detailed and schematic plots of protein structures , 1991 .

[50]  J. Zou,et al.  Improved methods for building protein models in electron density maps and the location of errors in these models. , 1991, Acta crystallographica. Section A, Foundations of crystallography.

[51]  J. Schittny,et al.  Heparin modulation of laminin polymerization. , 1990, The Journal of biological chemistry.

[52]  J Engel,et al.  Structure and function of laminin: anatomy of a multidomain glycoprotein , 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[53]  M. Paulsson.  The role of Ca2+ binding in the self-aggregation of laminin-nidogen complexes. , 1988, The Journal of biological chemistry.

[54]  R. Timpl,et al.  Protease resistance and conformation of laminin. , 1982, European journal of biochemistry.