Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology.
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[1] Yigong Shi. Caspase Activation Revisiting the Induced Proximity Model , 2004, Cell.
[2] Yigong Shi,et al. Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim , 2004, Nature Structural &Molecular Biology.
[3] R. Rich,et al. Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac* , 2003, Journal of Biological Chemistry.
[4] G. Salvesen,et al. Mechanisms of caspase activation. , 2003, Current opinion in cell biology.
[5] Christophe Briand,et al. Crystal Structure of Caspase-2, Apical Initiator of the Intrinsic Apoptotic Pathway* , 2003, Journal of Biological Chemistry.
[6] H. Horvitz,et al. NOBEL LECTURE: Worms, Life and Death , 2003, Bioscience reports.
[7] Yigong Shi,et al. Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination , 2003, Nature Structural Biology.
[8] H. Horvitz. Worms, Life, and Death (Nobel Lecture) , 2003, Chembiochem : a European journal of chemical biology.
[9] D. Green,et al. A unified model for apical caspase activation. , 2003, Molecular cell.
[10] C. Briand,et al. Insights into the regulatory mechanism for caspase-8 activation. , 2003, Molecular cell.
[11] S. Srinivasula,et al. Mechanism of XIAP-mediated inhibition of caspase-9. , 2003, Molecular cell.
[12] G. Gores,et al. Synthetic Smac/DIABLO Peptides Enhance the Effects of Chemotherapeutic Agents by Binding XIAP and cIAP1 in Situ * , 2002, The Journal of Biological Chemistry.
[13] Jun R Huh,et al. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms , 2002, Nature Cell Biology.
[14] R. Cagan,et al. Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1 , 2002, Nature Cell Biology.
[15] A. Ciechanover,et al. Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1 , 2002, Nature Cell Biology.
[16] Daniel A. Colón-Ramos,et al. Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition , 2002, Nature Cell Biology.
[17] G. Salvesen,et al. Apoptosis: IAP proteins: blocking the road to death's door , 2002, Nature Reviews Molecular Cell Biology.
[18] S. Lowe,et al. Generation and Characterization of Smac/DIABLO-Deficient Mice , 2002, Molecular and Cellular Biology.
[19] K. Lauber,et al. A caspase-related protease regulates apoptosis in yeast. , 2002, Molecular cell.
[20] G. Salvesen,et al. Reprieval from execution: the molecular basis of caspase inhibition. , 2002, Trends in biochemical sciences.
[21] Yigong Shi. A conserved tetrapeptide motif: potentiating apoptosis through IAP-binding , 2002, Cell Death and Differentiation.
[22] L. Schwartz,et al. Drosophila sickle Is a Novel grim-reaper Cell Death Activator , 2002, Current Biology.
[23] Michael Weller,et al. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo , 2002, Nature Medicine.
[24] G. Salvesen,et al. Structural basis for the activation of human procaspase-7 , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[25] R. Liddington,et al. Dimer formation drives the activation of the cell death protease caspase 9 , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[26] Yun-Ru Chen,et al. Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer. , 2001, Biochemistry.
[27] X. Wang. The expanding role of mitochondria in apoptosis. , 2001, Genes & development.
[28] Emad S. Alnemri,et al. Crystal Structure of a Procaspase-7 Zymogen Mechanisms of Activation and Substrate Binding , 2001, Cell.
[29] Yigong Shi,et al. Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. , 2001, Molecular cell.
[30] Emad S. Alnemri,et al. correction: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis , 2001, Nature.
[31] Stephanie Birkey Reffey,et al. Characterization of XIAP-Deficient Mice , 2001, Molecular and Cellular Biology.
[32] David G. Myszka,et al. Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex , 2001, Nature.
[33] R. Liddington,et al. Structural Basis for the Inhibition of Caspase-3 by XIAP , 2001, Cell.
[34] Young Chul Park,et al. Structural Basis of Caspase Inhibition by XIAP Differential Roles of the Linker versus the BIR Domain , 2001, Cell.
[35] S. Srinivasula,et al. Structural Basis of Caspase-7 Inhibition by XIAP , 2001, Cell.
[36] Emad S. Alnemri,et al. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis , 2001, Nature.
[37] G M Kasof,et al. Livin, a Novel Inhibitor of Apoptosis Protein Family Member* , 2001, The Journal of Biological Chemistry.
[38] Geng Wu,et al. Structural basis of IAP recognition by Smac/DIABLO , 2000, Nature.
[39] Stephen F. Betz,et al. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain , 2000, Nature.
[40] S. Srinivasula,et al. Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway* , 2000, The Journal of Biological Chemistry.
[41] B. Hay,et al. Understanding IAP function and regulation: a view from Drosophila , 2000, Cell Death and Differentiation.
[42] Junying Yuan,et al. Apoptosis in the nervous system , 2000, Nature.
[43] Xiaodong Wang,et al. Structural and biochemical basis of apoptotic activation by Smac/DIABLO , 2000, Nature.
[44] Xiaodong Wang,et al. Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition , 2000, Cell.
[45] Robert L Moritz,et al. Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins , 2000, Cell.
[46] K. Wilson,et al. The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity. , 2000, Chemistry & biology.
[47] J C Reed,et al. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[48] Y. Lazebnik,et al. Caspase-9 and APAF-1 form an active holoenzyme. , 1999, Genes & development.
[49] S. Nagata,et al. Fas ligand-induced apoptosis. , 1999, Annual review of genetics.
[50] J. Abrams. An emerging blueprint for apoptosis in Drosophila. , 1999, Trends in cell biology.
[51] Stephen W. Fesik,et al. NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP , 1999, Nature.
[52] G. Salvesen,et al. Caspase activation: the induced-proximity model. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[53] A. Tomasselli,et al. The atomic-resolution structure of human caspase-8, a key activator of apoptosis. , 1999, Structure.
[54] Emad S. Alnemri,et al. Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1 , 1999, Nature.
[55] J C Reed,et al. Caspase-9 Can Be Activated without Proteolytic Processing* , 1999, The Journal of Biological Chemistry.
[56] J C Reed,et al. IAP family proteins--suppressors of apoptosis. , 1999, Genes & development.
[57] M. Lutter,et al. Biochemical pathways of caspase activation during apoptosis. , 1999, Annual review of cell and developmental biology.
[58] D. Baltimore,et al. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. , 1998, Science.
[59] Y. Lazebnik,et al. Caspases: enemies within. , 1998, Science.
[60] Xiaodong Wang,et al. Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors , 1998, Cell.
[61] Junying Yuan,et al. Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis , 1998, Cell.
[62] S. Srinivasula,et al. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. , 1998, Molecular cell.
[63] G. Sirugo,et al. Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting* , 1998, The Journal of Biological Chemistry.
[64] D. Spencer,et al. Synthetic activation of caspases: artificial death switches. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[65] Brent R. Stockwell,et al. An Induced Proximity Model for Caspase-8 Activation* , 1998, The Journal of Biological Chemistry.
[66] D. Baltimore,et al. Autoproteolytic activation of pro-caspases by oligomerization. , 1998, Molecular cell.
[67] S. Srinivasula,et al. Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.
[68] D. Altieri,et al. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma , 1997, Nature Medicine.
[69] M. Grütter,et al. Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone* , 1997, The Journal of Biological Chemistry.
[70] N. Thornberry,et al. The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis , 1996, Nature Structural Biology.
[71] C. Thompson,et al. Apoptosis in the pathogenesis and treatment of disease , 1995, Science.
[72] J. Mankovich,et al. Crystal structure of the cysteine protease interleukin-1β-converting enzyme: A (p20/p10)2 homodimer , 1994, Cell.
[73] Mark A. Murcko,et al. Structure and mechanism of interleukin-lβ converting enzyme , 1994, Nature.
[74] A. Wyllie,et al. Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.