Optimization of Cardiac Resynchronization Therapy by Continuous Hemodynamic Monitoring:

We report the case of a 55‐year‐old male patient with severe congestive heart failure in whom both a hemodynamic monitor and a biventricular pacemaker were implanted. The potential usefulness of the monitor to optimize AV delay and heart rate was prospectively evaluated. The AV delay associated with the lowest filling pressures recorded by the monitor was similar to the optimal AV delay as determined by standard echocardiography. Heart rates >70 beats/min acutely improved hemodynamics but were not tolerated when programmed chronically. This case illustrates that continuous hemodynamic monitoring may offer a useful tool for device tuning and treatment monitoring in cardiac resynchronization therapy. (J Cardiovasc Electrophysiol, Vol. 15, pp. 94‐96, January 2004)

[1]  L. Rydén,et al.  Monitoring of pulmonary arterial diastolic pressure through a right ventricular pressure transducer. , 1995, Journal of cardiac failure.

[2]  R. Wilson,et al.  Measurement of pulmonary artery diastolic pressure from a right ventricular pressure transducer in patients with heart failure. , 1996, Journal of cardiac failure.

[3]  J. Leitch,et al.  The Importance of the Left Atrioventricular Interval during Atrioventricular Sequential Pacing , 1997, Pacing and clinical electrophysiology : PACE.

[4]  P. Ritter,et al.  Indications for Permanent Pacing and Choice of Pacemaker , 1998 .

[5]  L. Padeletti,et al.  Determination of the optimal atrioventricular delay in DDD pacing. Comparison between echo and peak endocardial acceleration measurements. , 1999, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[6]  J. Daubert,et al.  Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. , 2001, The New England journal of medicine.

[7]  D. Delurgio,et al.  Cardiac resynchronization in chronic heart failure. , 2002, The New England journal of medicine.

[8]  Lars Rydén,et al.  Continous haemodynamic monitoring during withdrawal of diuretics in patients with congestive heart failure , 2002 .

[9]  L. Rydén,et al.  Continuous haemodynamic monitoring during withdrawal of diuretics in patients with congestive heart failure. , 2002, European heart journal.

[10]  Philip Adamson,et al.  Continuous ambulatory right heart pressure measurements with an implantable hemodynamic monitor: a multicenter, 12-month follow-up study of patients with chronic heart failure. , 2002, Journal of cardiac failure.

[11]  F. Braunschweig,et al.  Continuous Hemodynamic Monitoring in Heart Failure , 2002, Journal of cardiovascular electrophysiology.

[12]  Milton Packer,et al.  Cardiac resynchronization in chronic heart failure. , 2002, The New England journal of medicine.

[13]  L. Rydén,et al.  Ongoing right ventricular hemodynamics in heart failure: clinical value of measurements derived from an implantable monitoring system. , 2003, Journal of the American College of Cardiology.