Robust Learning-Based Annotation of Medical Radiographs

In this paper, we propose a learning-based algorithm for automatic medical image annotation based on sparse aggregation of learned local appearance cues, achieving high accuracy and robustness against severe diseases, imaging artifacts, occlusion, or missing data. The algorithm starts with a number of landmark detectors to collect local appearance cues throughout the image, which are subsequently verified by a group of learned sparse spatial configuration models. In most cases, a decision could already be made at this stage by simply aggregating the verified detections. For the remaining cases, an additional global appearance filtering step is employed to provide complementary information to make the final decision. This approach is evaluated on a large-scale chest radiograph view identification task, demonstrating an almost perfect performance of 99.98% for a posteroanterior/anteroposterior (PA-AP) and lateral view position identification task, compared with the recently reported large-scale result of only 98.2% [1]. Our approach also achieved the best accuracies for a three-class and a multi-class radiograph annotation task, when compared with other state of the art algorithms. Our algorithm has been integrated into an advanced image visualization workstation, enabling content-sensitive hanging-protocols and auto-invocation of a computer aided detection algorithm for PA-AP chest images.

[1]  Thomas Martin Deserno,et al.  Automatic medical image annotation in ImageCLEF 2007: Overview, results, and discussion , 2008, Pattern Recognit. Lett..

[2]  Chungnan Lee,et al.  Projection profile analysis for identifying different views of chest radiographs. , 2006, Academic radiology.

[3]  Hermann Ney,et al.  Deformation Models for Image Recognition , 2007, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[4]  Matthijs C. Dorst Distinctive Image Features from Scale-Invariant Keypoints , 2011 .

[5]  Barbara Caputo,et al.  Discriminative cue integration for medical image annotation , 2008, Pattern Recognit. Lett..

[6]  Fredric C. Gey,et al.  ENSM-SE at CLEF 2006 : Fuzzy Proximity Method with an Adhoc Influence Function in Evaluation of Multilingual and Multi-modal Information Retrieval 7th Workshop of the Cross-Language Evaluation Forum, CLEF 2006, Alicante, Spain , 2007 .

[7]  Yoav Freund,et al.  A decision-theoretic generalization of on-line learning and an application to boosting , 1995, EuroCOLT.

[8]  Thomas Martin Deserno,et al.  Baseline Results for the ImageCLEF 2006 Medical Automatic Annotation Task , 2006, CLEF.

[9]  F. Netter Atlas of Human Anatomy , 1967 .

[10]  Yiqiang Zhan,et al.  Active Scheduling of Organ Detection and Segmentation in Whole-Body Medical Images , 2008, MICCAI.

[11]  Paul A. Viola,et al.  Rapid object detection using a boosted cascade of simple features , 2001, Proceedings of the 2001 IEEE Computer Society Conference on Computer Vision and Pattern Recognition. CVPR 2001.

[12]  Tobias Gass,et al.  Performing Image Classification with a Frequency-based Information Retrieval Schema for ImageCLEF 2006 , 2006, CLEF.

[13]  Hermann Ney,et al.  Deformations, patches, and discriminative models for automatic annotation of medical radiographs , 2008, Pattern Recognit. Lett..

[14]  Gabor Fichtinger,et al.  Medical Image Computing and Computer-Assisted Intervention - MICCAI 2008, 11th International Conference, New York, NY, USA, September 6-10, 2008, Proceedings, Part I , 2008, International Conference on Medical Image Computing and Computer-Assisted Intervention.

[15]  H. K. Huang,et al.  Orientation correction for chest images , 1992, Journal of Digital Imaging.

[16]  Thomas Martin Deserno,et al.  Baseline Results for the ImageCLEF 2007 Medical Automatic Annotation Task Using Global Image Features , 2007, CLEF.

[17]  Hui Luo,et al.  Automatic image hanging protocol for chest radiographs in PACS , 2006, IEEE Transactions on Information Technology in Biomedicine.

[18]  Kunio Doi,et al.  Performance evaluation of an advanced method for automated identification of view positions of chest radiographs by use of a large database , 2002, SPIE Medical Imaging.

[19]  John M. Boone,et al.  Automated Recognition of Lateral from PA Chest Radiographs: Saving Seconds in a PACS Environment , 2003, Journal of Digital Imaging.

[20]  Thomas Martin Deserno,et al.  Determining the View of Chest Radiographs , 2003, Journal of Digital Imaging.

[21]  Tobias Gass,et al.  Image Classification with a Frequency-Based Information Retrieval Scheme for ImageCLEFmed 2006 , 2006, CLEF.