What you count is what you target: the implications of maternal death classification for tracking progress towards reducing maternal mortality in developing countries.

The first target of the fifth United Nations Millennium Development Goal is to reduce maternal mortality by 75% between 1990 and 2015. This target is critically off track. Despite difficulties inherent in measuring maternal mortality, interventions aimed at reducing it must be monitored and evaluated to determine the most effective strategies in different contexts. In some contexts, the direct causes of maternal death, such as haemorrhage and sepsis, predominate and can be tackled effectively through providing access to skilled birth attendance and emergency obstetric care. In others, indirect causes of maternal death, such as HIV/AIDS and malaria, make a significant contribution and require alternative interventions. Methods of planning and evaluating maternal health interventions that do not differentiate between direct and indirect maternal deaths may lead to unrealistic expectations of effectiveness or mask progress in tackling specific causes. Furthermore, the need for additional or alternative interventions to tackle the causes of indirect maternal death may not be recognized if all-cause maternal death is used as the sole outcome indicator. This article illustrates the importance of differentiating between direct and indirect maternal deaths by analysing historical data from England and Wales and contemporary data from Ghana, Rwanda and South Africa. The principal aim of the paper is to highlight the need to differentiate deaths in this way when evaluating maternal mortality, particularly when judging progress towards the fifth Millennium Development Goal. It is recommended that the potential effect of maternity services failing to take indirect maternal deaths into account should be modelled.

[1]  C. Escoffery,et al.  Epidemiologic transition in maternal mortality and morbidity: New challenges for Jamaica , 2007, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[2]  T. Clutton-Brock,et al.  Saving Mothers’ Lives: Reviewing Maternal Deaths to Make Motherhood Safer 2006-2008 A Review , 2012 .

[3]  O. Campbell,et al.  Measuring maternal mortality: An overview of opportunities and options for developing countries , 2008, BMC medicine.

[4]  C. Menéndez,et al.  Clinico-Pathological Discrepancies in the Diagnosis of Causes of Maternal Death in Sub-Saharan Africa: Retrospective Analysis , 2009, PLoS medicine.

[5]  D. Chandramohan,et al.  Unstable malaria transmission and maternal mortality – experiences from Rwanda , 2002, Tropical medicine & international health : TM & IH.

[6]  W. Graham,et al.  Missing maternal deaths: Lessons from Souro Sanou University Hospital in Bobo-Dioulasso, Burkina Faso , 2007, Tropical doctor.

[7]  P. Byass,et al.  Revealing the burden of maternal mortality: a probabilistic model for determining pregnancy-related causes of death from verbal autopsies , 2007, Population health metrics.

[8]  C. AbouZahr Global burden of maternal death and disability. , 2003, British medical bulletin.

[9]  Michael A. Clemens,et al.  The Trouble with the MDGS: Confronting Expectations of Aid and Development Success , 2004 .

[10]  J. Haukoos,et al.  Recognition of undiagnosed HIV infection: an evaluation of missed opportunities in a predominantly urban minority population. , 2005, AIDS patient care and STDs.

[11]  S. Africa. Ten key recommendations from the third report on confidential enquiries into maternal deaths in South Africa 2002-2004 : recommendations , 2006 .

[12]  S. Anya Seasonal variation in the risk and causes of maternal death in the Gambia: malaria appears to be an important factor. , 2004, The American journal of tropical medicine and hygiene.

[13]  C. AbouZahr,et al.  Estimates of maternal mortality worldwide between 1990 and 2005: an assessment of available data , 2007, The Lancet.

[14]  Programme Manager's Planning Monitoring & Evaluation Toolkit Tool Number 4: Stakeholder Participation in Monitoring and Evaluation , 2022 .

[15]  O. Campbell,et al.  Strategies for reducing maternal mortality: getting on with what works , 2006, The Lancet.

[16]  D. Maine,et al.  The design and evaluation of maternal mortality programs. , 1997 .

[17]  C. Ronsmans,et al.  The effect of AIDS on maternal mortality in Malawi and Zimbabwe. , 2002, AIDS.

[18]  A Metin Gülmezoglu,et al.  WHO analysis of causes of maternal death: a systematic review , 2006, The Lancet.

[19]  Cemach Saving mothers' lives: reviewing maternal deaths to make motherhood safer - 2003-2005 , 2007 .

[20]  L. D’Ambruoso,et al.  Maternal health in the year 2076 , 2008, The Lancet.

[21]  Miranda Mugford,et al.  Birth Counts: Statistics of Pregnancy and Childbirth , 1984 .

[22]  A. Fitzmaurice,et al.  Evaluation of the delivery fee exemption policy in ghana: population estimates of changes in delivery service utilization in two regions. , 2007, Ghana medical journal.

[23]  C. Ronsmans,et al.  Verbal autopsies for maternal deaths. World Health Organization workshop held at the London School of Hygiene and Tropical Medicine 10-13 January 1994 London U.K. , 1995 .

[24]  C. Ronsmans,et al.  Seasonal variation in direct obstetric mortality in rural Senegal: role of malaria? , 2003, The American journal of tropical medicine and hygiene.

[25]  J. Bell,et al.  Effect of delivery care user fee exemption policy on institutional maternal deaths in the central and volta regions of ghana. , 2010, Ghana medical journal.

[26]  O. Campbell,et al.  Measuring progress in reducing maternal mortality. , 2008, Best practice & research. Clinical obstetrics & gynaecology.