Evaluation of efficacy of a herbal dentifrice on dentinal hypersensitivity: A clinical study

Background: Dentinal hypersensitivity is a one of the leading dental problems and herbal based formulations have been in use recently for the same. Objective: This study was conducted for the evaluation of the safety and efficacy of a novel herbal toothpaste in reduction of dentinal hypersensitivity in vivo. Materials and Methods: A total of12 subjects were randomly taken into consideration as a single group. Brushing instructions were given for 7 days use of toothpaste to all subjects. Sensitivity scores for tactile, air stimulus and cold water were recorded at baseline, 3rd and 7th day for the study subjects. Results: There was a significant reduction seen in the clinical parameters evaluated in all subjects at the end of the period of use of the toothpaste compared to baseline. Conclusion: The novel herbal dentifrice can be recommended for treatment of dentinal hypersensitivity. Keywords: Dentinal, Herbal dentifrice, Hypersensitivity.

[1]  H. Horner,et al.  Calcium oxalate crystals in plants , 1980, The Botanical Review.

[2]  E. Baran,et al.  Characterization of Calcium Oxalates Generated as Biominerals in Cacti1 , 2002, Plant Physiology.

[3]  C. Prati,et al.  Dentin morphology and permeability after brushing with different toothpastes in the presence and absence of smear layer. , 2002, Journal of periodontology.

[4]  J. C. Pereira,et al.  TREATING HYPERSENSITIVE DENTIN WITH THREE DIFFERENT POTASSIUM OXALATE- BASED GEL FORMULATIONS: A CLINICAL STUDY , 2002 .

[5]  J. Knowles,et al.  The effects of oxalate-containing products on the exposed dentine surface: an SEM investigation. , 2001, Journal of oral rehabilitation.

[6]  R. Holmes,et al.  Estimation of the oxalate content of foods and daily oxalate intake. , 2000, Kidney international.

[7]  R. Orchardson,et al.  The efficacy of potassium salts as agents for treating dentin hypersensitivity. , 2000, Journal of orofacial pain.

[8]  D. Pashley,et al.  Dentin permeability after toothbrushing with different toothpastes. , 1999, American journal of dentistry.

[9]  M. F. Morris,et al.  Clinical efficacy of two dentin desensitizing agents. , 1999, American journal of dentistry.

[10]  D. Gillam,et al.  The dentine disc. A review of its applicability as a model for the in vitro testing of dentine hypersensitivity. , 1997, Journal of oral rehabilitation.

[11]  L. Rimondini,et al.  Ultrastructure of hypersensitive and non-sensitive dentine. A study on replica models. , 1995, Journal of clinical periodontology.

[12]  J Arends,et al.  The diameter of dentinal tubules in human coronal dentine after demineralization and air drying. A combined light microscopy and SEM study. , 1995, Caries research.

[13]  C. Prati.  What is the clinical relevance of in vitro dentine permeability tests? , 1994, Journal of dentistry.

[14]  C. Prati,et al.  Mineralogical and crystallographical study of γ-calcium oxalate on dentine surfaces in vitro , 1994 .

[15]  D. Pashley.  Dentine permeability and its role in the pathobiology of dentine sensitivity. , 1994, Archives of oral biology.

[16]  D. Pashley,et al.  Dentinal tubule occlusion and root hypersensitivity. , 1991, Journal of periodontology.

[17]  K. Muzzin,et al.  Effects of potassium oxalate on dentin hypersensitivity in vivo. , 1989, Journal of periodontology.

[18]  D. Pashley,et al.  Scanning electron microscopy of the substructure of smear layers in human dentine. , 1988, Archives of oral biology.

[19]  D. Pashley,et al.  The effects of burnishing NaF/kaolin/glycerin paste on dentin permeability. , 1987, Journal of periodontology.

[20]  D. Pashley.  Dentin permeability, dentin sensitivity, and treatment through tubule occlusion. , 1986, Journal of endodontics.

[21]  M. Addy,et al.  Dentine hypersensitivity: aetiology, differential diagnosis and management , 1985, British Dental Journal.

[22]  D. Pashley,et al.  The effects of oxalate treatment on the smear layer of ground surfaces of human dentine. , 1985, Archives of oral biology.

[23]  D. Pashley,et al.  Dentin permeability. Effects of desensitizing dentifrices in vitro. , 1984, Journal of periodontology.

[24]  H. Arnott.  Three Systems of Biomineralization in Plants with Comments on the Associated Organic Matrix , 1982 .

[25]  D. Pashley,et al.  The Effects of Desensitizing Agents on the Hydraulic Conductance of Human Dentin in vitro , 1981, Journal of dental research.