New insights and updated guidelines for epigenome-wide association studies

[1]  Bastiaan T. Heijmans,et al.  From promises to practical strategies in epigenetic epidemiology , 2013, Nature Reviews Genetics.

[2]  Gavin Giovannoni,et al.  Inactive or moderately active human promoters are enriched for inter-individual epialleles , 2013, Genome Biology.

[3]  J. Montaner,et al.  DNA Isolation Method Is a Source of Global DNA Methylation Variability Measured with LUMA. Experimental Analysis and a Systematic Review , 2013, PloS one.

[4]  Timothy E. Reddy,et al.  Dynamic DNA methylation across diverse human cell lines and tissues , 2013, Genome research.

[5]  T. Miyakawa,et al.  Genomic responses in mouse models poorly mimic human inflammatory diseases , 2013 .

[6]  Martin J. Aryee,et al.  A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression , 2013, Epigenetics.

[7]  R. Gamelli,et al.  Genomic responses in mouse models poorly mimic human inflammatory diseases , 2013, Proceedings of the National Academy of Sciences.

[8]  Martin J. Aryee,et al.  Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in Rheumatoid Arthritis , 2013, Nature Biotechnology.

[9]  Vilmundur Gudnason,et al.  Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements , 2012, PloS one.

[10]  F. Lyko,et al.  Epigenetic cancer therapy: rationales, targets and drugs , 2012, Oncogene.

[11]  Gautier Koscielny,et al.  Analysis of variation at transcription factor binding sites in Drosophila and humans , 2012, Genome Biology.

[12]  Susan K. Murphy,et al.  450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy , 2012, Environmental health perspectives.

[13]  M. Dawson,et al.  Cancer Epigenetics: From Mechanism to Therapy , 2012, Cell.

[14]  Lee E. Edsall,et al.  A map of the cis-regulatory sequences in the mouse genome , 2012, Nature.

[15]  P. Laird,et al.  Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships , 2012, Human Genetics.

[16]  P. Gluckman,et al.  Developmental origins of non-communicable disease: Implications for research and public health , 2012, Environmental Health.

[17]  Alfonso Valencia,et al.  Distinct DNA methylomes of newborns and centenarians , 2012, Proceedings of the National Academy of Sciences.

[18]  Mukesh Verma,et al.  Epigenome-Wide Association Studies (EWAS) in Cancer , 2012, Current genomics.

[19]  Devin C. Koestler,et al.  DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.

[20]  J. Licht,et al.  Emerging epigenetic targets and therapies in cancer medicine. , 2012, Cancer discovery.

[21]  Dan Wang,et al.  IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data , 2012, Bioinform..

[22]  L. Hou,et al.  Environmental chemical exposures and human epigenetics. , 2012, International journal of epidemiology.

[23]  P. Falkai,et al.  Methyl- and acetyltransferases are stable epigenetic markers postmortem , 2011, Cell and Tissue Banking.

[24]  A. Dueñas-González,et al.  Pharmacokinetics of hydralazine, an antihypertensive and DNA-demethylating agent, using controlled-release formulations designed for use in dosing schedules based on the acetylator phenotype. , 2011, International journal of clinical pharmacology and therapeutics.

[25]  Kevin M. Bowling,et al.  Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation , 2011, PLoS genetics.

[26]  D. Balding,et al.  Epigenome-wide association studies for common human diseases , 2011, Nature Reviews Genetics.

[27]  Julie Herbstman,et al.  Prenatal environmental exposures, epigenetics, and disease. , 2011, Reproductive Toxicology.

[28]  Tim D. Spector,et al.  A twin approach to unraveling epigenetics , 2011, Trends in genetics : TIG.

[29]  P. Gluckman,et al.  The role of developmental plasticity and epigenetics in human health. , 2011, Birth defects research. Part C, Embryo today : reviews.

[30]  David M. Simcha,et al.  Tackling the widespread and critical impact of batch effects in high-throughput data , 2010, Nature Reviews Genetics.

[31]  Dirk Schübeler,et al.  Tackling the epigenome: challenges and opportunities for collaboration , 2010, Nature Biotechnology.

[32]  T. Mikkelsen,et al.  The NIH Roadmap Epigenomics Mapping Consortium , 2010, Nature Biotechnology.

[33]  Luigi Ferrucci,et al.  Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain , 2010, PLoS genetics.

[34]  S. Ozanne,et al.  Mechanisms involved in the developmental programming of adulthood disease. , 2010, The Biochemical journal.

[35]  R. Yuen,et al.  Human Placental-Specific Epipolymorphism and its Association with Adverse Pregnancy Outcomes , 2009, PloS one.

[36]  J. Borlak,et al.  The next innovation cycle in toxicogenomics: environmental epigenetics. , 2008, Mutation research.

[37]  R. Waterland,et al.  Epigenetic epidemiology of the developmental origins hypothesis. , 2007, Annual review of nutrition.

[38]  Stanley J. Watson,et al.  Methodological considerations for gene expression profiling of human brain , 2007, Journal of Neuroscience Methods.

[39]  N. Risch,et al.  Dissecting complex diseases in complex populations: asthma in latino americans. , 2007, Proceedings of the American Thoracic Society.

[40]  M. Esteller.  Cancer epigenomics: DNA methylomes and histone-modification maps , 2007, Nature Reviews Genetics.

[41]  Claudine Junien,et al.  Impact of diets and nutrients/drugs on early epigenetic programming , 2006, Journal of Inherited Metabolic Disease.

[42]  P. Laird,et al.  Sex differential in methylation patterns of selected genes in Singapore Chinese , 2005, Human Genetics.

[43]  A. Feinberg,et al.  Loss of IGF2 Imprinting: A Potential Marker of Colorectal Cancer Risk , 2003, Science.

[44]  M. Vazquez,et al.  Analysis of the methylation status of the KCNQ1OT and H19 genes in leukocyte DNA for the diagnosis and prognosis of Beckwith–Wiedemann syndrome , 2001, European Journal of Human Genetics.

[45]  S. Gore,et al.  Epigenetic therapies in MDS and AML. , 2013, Advances in experimental medicine and biology.