Evolutionary Origins of the Transforming Growth Factor-β Gene Family

ABSTRACT A molecular phylogeny for the transforming growth factor-β (TGF-β) gene family based on a comparison of nucleotide sequences is proposed. A phylogenetic tree constructed from these sequenc...

[1]  D. Burt,et al.  Correction: a new interpretation of a chicken transforming growth factor-beta 4 complementary DNA. , 1992, Molecular endocrinology.

[2]  D. Burt,et al.  Molecular cloning and primary structure of the chicken transforming growth factor-β2 gene , 1991 .

[3]  W. Gelbart,et al.  Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[4]  J. McPherson,et al.  Bone morphogenetic protein: chromosomal localization of human genes for BMP1, BMP2A, and BMP3. , 1991, Genomics.

[5]  E. Canalis,et al.  Recombinant transforming growth factor type beta 3: biological activities and receptor-binding properties in isolated bone cells , 1990, Molecular and cellular biology.

[6]  A. Roberts,et al.  cDNA cloning by PCR of rat transforming growth factor β-1 , 1990 .

[7]  I. Dawid,et al.  The sequence of TGF-β2 from Xenopus laevis , 1990 .

[8]  M. Dickinson,et al.  Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci. , 1990, Genomics.

[9]  M. Sporn,et al.  Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis. , 1990, The Journal of biological chemistry.

[10]  E. Chen,et al.  Complementary DNA Cloning of the Murine Transforming Growth Factor-β3 (TGFβ3) Precursor and the Comparative Expression of TGFβ3 and TGFβ1 Messenger RNA in Murine Embryos and Adult Tissues , 1989 .

[11]  R. Derynck,et al.  Human Transforming Growth Factor- β3: Recombinant Expression, Purification, and Biological Activities in Comparison with Transforming Growth Factors-β 1 and -β2 , 1989 .

[12]  E. Chen,et al.  Murine transforming growth factor-beta 2 cDNA sequence and expression in adult tissues and embryos. , 1989, Molecular endocrinology.

[13]  M. Sporn,et al.  Complementary deoxyribonucleic acid cloning of a messenger ribonucleic acid encoding transforming growth factor beta 4 from chicken embryo chondrocytes. , 1988, Molecular endocrinology.

[14]  R. Derynck,et al.  A new type of transforming growth factor‐beta, TGF‐beta 3. , 1988, The EMBO journal.

[15]  M. Sporn,et al.  Nucleotide sequence of chicken transforming growth factor-beta 1 (TGF-β 1) , 1988 .

[16]  M. Sporn,et al.  SEQUENCES OF INTEREST: Complementary Deoxyribonucleic Acid Cloning of a Novel Transforming Growth Factor-β Messenger Ribonucleic Acid from Chick Embryo Chondrocytes , 1988 .

[17]  M. Sporn,et al.  Complementary deoxyribonucleic acid cloning of bovine transforming growth factor-beta 1. , 1987, Molecular endocrinology.

[18]  G. Plowman,et al.  Cloning and Sequence Analysis of Simian Transforming Growth Factor-β cDNA , 1987 .

[19]  E. Chen,et al.  Intron-exon structure of the human transforming growth factor-β precursor gene , 1987 .

[20]  R. Derynck,et al.  Sequence of the porcine transforming growth factor-beta precursor. , 1987, Nucleic acids research.

[21]  E. Chen,et al.  The murine transforming growth factor-beta precursor. , 1986, The Journal of biological chemistry.

[22]  Anita B. Roberts,et al.  Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells , 1985, Nature.

[23]  C. Luo,et al.  A new method for estimating synonymous and nonsynonymous rates of nucleotide substitution considering the relative likelihood of nucleotide and codon changes. , 1985, Molecular biology and evolution.

[24]  J. Devereux,et al.  A comprehensive set of sequence analysis programs for the VAX , 1984, Nucleic Acids Res..

[25]  A. Feinberg,et al.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. , 1983, Analytical biochemistry.

[26]  T. Miyata,et al.  Nucleotide sequence divergence and functional constraint in mRNA evolution. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Sporn,et al.  Expression of transforming growth factor-beta s 1-4 in chicken embryo chondrocytes and myocytes. , 1991, Developmental biology.

[28]  M. Sporn,et al.  Complementary deoxyribonucleic acid cloning of an mRNA encoding transforming growth factor-beta 2 from chicken embryo chondrocytes. , 1990, Growth factors.

[29]  R. Derynck,et al.  Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family. , 1988, Oncogene research.

[30]  S. Hanks,et al.  Amino acid sequence of the BSC-1 cell growth inhibitor (polyergin) deduced from the nucleotide sequence of the cDNA. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[31]  M. Kimura Estimation of evolutionary distances between homologous nucleotide sequences. , 1981, Proceedings of the National Academy of Sciences of the United States of America.