Interpretation of Imprecision in Medical Data

Imprecision is an intrinsic part of all data types and even more so of medical data. In this paper, we revisit the definition of imprecision as well as closely related concepts of incompleteness, uncertainty, inaccuracy, and, in general, imperfection of data. We examine the traditional hierarchical approach to data, information, and knowledge in the context of medical data, which is characterized by heterogeneity, variable granularity and time-dependency. We observe that (1) imprecision has syntactic, semantic, and pragmatic aspects and (2) imprecision has its spectrum from most precise to most imprecise and unknown. We argue that interpretation of imprecision is highly contextual, and, furthermore, that medical data cannot be decoupled from their meanings and their intended usage. To address the contextual interpretation of imprecision, we present a framework for knowledge-based modeling of medical data, which comprises a semiotic approach, a fuzzy-logic approach, and a multidimensional approach.

[1]  Valentin Robu,et al.  An introduction to the Semantic Web for health sciences librarians. , 2006, Journal of the Medical Library Association : JMLA.

[2]  Amihai Motro,et al.  Accommodating imprecision in database systems: issues and solutions , 1990, SGMD.

[3]  Sheng-Cheng Huang,et al.  A semiotic view of information: Semiotics as a foundation of LIS research in information behavior , 2007, ASIST.

[4]  Daniel Sánchez,et al.  F-Cube Factory: a Fuzzy OLAP System for Supporting Imprecision , 2007, Int. J. Uncertain. Fuzziness Knowl. Based Syst..

[5]  Alvan R. Feinstein,et al.  Principles of Medical Statistics , 2001 .

[6]  Heinz J. Skala,et al.  On the problem of imprecision , 1976 .

[7]  Amihai Motro,et al.  VAGUE: a user interface to relational databases that permits vague queries , 1988, TOIS.

[8]  M. Carskadon,et al.  Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness. , 1986, Sleep.

[9]  Richard T. Watson,et al.  Data Management, Databases and Organizations , 2008 .

[10]  Torben Bach Pedersen,et al.  Supporting imprecision in multidimensional databases using granularities , 1999, Proceedings. Eleventh International Conference on Scientific and Statistical Database Management.

[11]  Philippe Smets,et al.  Imperfect Information: Imprecision and Uncertainty , 1996, Uncertainty Management in Information Systems.

[12]  E. de Valck,et al.  Sleepiness as a state-trait phenomenon, comprising both a sleep drive and a wake drive. , 2003, Medical hypotheses.

[13]  Simon Parsons,et al.  Addendum to "Current Approaches to Handling Imperfect Information in Data and Knowledge Bases" , 1996, IEEE Trans. Knowl. Data Eng..

[14]  Jerzy W. Grzymala-Busse,et al.  Rough Sets , 1995, Commun. ACM.

[15]  Lotfi A. Zadeh,et al.  Fuzzy Sets , 1996, Inf. Control..

[16]  R. M. Cantor Foundations of Roentgen semiotics , 2000 .

[17]  Kei-Hoi Cheung,et al.  Advancing translational research with the Semantic Web , 2007, BMC Bioinformatics.

[18]  Ewa Straszecka,et al.  Combining uncertainty and imprecision in models of medical diagnosis , 2006, Inf. Sci..

[19]  Miquel Porta,et al.  A Dictionary of Epidemiology , 2008 .

[20]  R. M. Cantor Diagnostic logic in Roentgen semiotics , 2004 .

[21]  Edward H. Shortliffe,et al.  Medical data: their acquisition, storage, and use , 1990 .

[22]  Piero P. Bonissone,et al.  Editorial: Reasoning with Uncertainty in Expert Systems , 1985, Int. J. Man Mach. Stud..

[23]  Vesa A. Niskanen Soft computing methods in human sciences , 2004 .

[24]  I. McDowell,et al.  Measuring health: A guide to rating scales and questionnaires, 3rd ed. , 2006 .