School-Age Outcomes in Children with Birth Weights under 750 g

Background Since the mid-1980s, increasing numbers of children with birth weights under 750 g have survived to school age. Methods We matched a regional cohort of 68 surviving children born from 1982 through 1986 with birth weights under 750 g (mean, 670 g; gestational age, 25.7 weeks) with 65 children weighing 750 to 1499 g at birth and 61 children born at term. Growth, neurosensory status, and functioning at school age in the three groups were compared. Associations of biologic and social risk factors with major developmental outcomes were examined by means of logistic-regression analyses. Results Children with birth weights under 750 g were inferior to both comparison groups in cognitive ability, psychomotor skills, and academic achievement. They had poorer social skills and adaptive behavior and more behavioral and attention problems. The mean (±SD) Mental Processing Composite score for the cohort was 87 ±15, as compared with 93 ±14 for children with birth weights of 750 to 1499 g and 100 ±13 for chil...

[1]  A. Edwards,et al.  RELATION BETWEEN ULTRASOUND APPEARANCE OF THE BRAIN OF VERY PRETERM INFANTS AND NEURODEVELOPMENTAL IMPARIMENT AT EIGHT YEARS , 1993, Developmental medicine and child neurology.

[2]  A. Ohlsson,et al.  Abnormal pulmonary outcomes in premature infants: prediction from oxygen requirement in the neonatal period. , 1988, Pediatrics.

[3]  J. Horbar,et al.  Decreasing mortality associated with the introduction of surfactant therapy: an observational study of neonates weighing 601 to 1300 grams at birth. The Members of the National Institute of Child Health and Human Development Neonatal Research Network. , 1993, Pediatrics.

[4]  C. Schatschneider,et al.  Sequelae of Haemophilus Influenzae Meningitis: Implications for the Study of Brain Disease and Development , 1992 .

[5]  J D Horbar,et al.  Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Network. , 1991, Pediatrics.

[6]  T. Hirata,et al.  Survival and outcome of infants 501 to 750 gm: a six-year experience. , 1983, The Journal of pediatrics.

[7]  D Mukherjee,et al.  Head circumference reference data: birth to 18 years. , 1987, Pediatrics.

[8]  D. Aram,et al.  Effect of very low birth weight and subnormal head size on cognitive abilities at school age. , 1991, The New England journal of medicine.

[9]  B. Sachs,et al.  Postirradiation treatment outcomes for children with acute lymphocytic leukemia: clarification of risks. , 1987, Journal of pediatric psychology.

[10]  A. Wilkinson,et al.  Functional abilities at age 4 years of children born before 29 weeks of gestation. , 1993, BMJ.

[11]  A. Fanaroff,et al.  Outcomes of extremely-low-birth-weight infants between 1982 and 1988. , 1989, The New England journal of medicine.

[12]  J. Fletcher.  Memory for verbal and nonverbal stimuli in learning disability subgroups: analysis by selective reminding. , 1985, Journal of experimental child psychology.

[13]  W. Allan,et al.  Intraventricular hemorrhage in preterm infants: declining incidence in the 1980s. , 1989, Pediatrics.

[14]  S. Sheps,et al.  Retinopathy of prematurity-induced blindness: birth weight-specific survival and the new epidemic. , 1990, Pediatrics.

[15]  E. Goldson,et al.  Eight-year school performance, neurodevelopmental, and growth outcome of neonates with bronchopulmonary dysplasia: a comparative study. , 1992, Pediatrics.

[16]  P Szatmari,et al.  Cognitive abilities and school performance of extremely low birth weight children and matched term control children at age 8 years: a regional study. , 1991, The Journal of pediatrics.

[17]  R. Barkley,et al.  Attention Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment , 1994 .

[18]  F. McLean,et al.  Intrauterine growth of live-born Caucasian infants at sea level: standards obtained from measurements in 7 dimensions of infants born between 25 and 44 weeks of gestation. , 1969, The Journal of pediatrics.

[19]  P. Auld,et al.  Survival and outcome of infants weighing <800 grams at birth , 1990 .

[20]  L. Papile,et al.  Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. , 1978, The Journal of pediatrics.

[21]  A. Kaufman,et al.  Short Forms of the K-ABC Mental Processing and Achievement Scales at Ages 4 to 12½ Years for Clinical and Screening Purposes , 1988 .

[22]  H. Taylor,et al.  Pseudoword repetition ability in learning-disabled children , 1989, Applied Psycholinguistics.

[23]  W M Moore,et al.  Physical growth: National Center for Health Statistics percentiles. , 1979, The American journal of clinical nutrition.

[24]  B. Vohr,et al.  Effects of intraventricular hemorrhage and socioeconomic status on perceptual, cognitive, and neurologic status of low birth weight infants at 5 years of age. , 1992, The Journal of pediatrics.

[25]  H. Whyte,et al.  Ocular sequelae in premature infants. , 1993, Pediatrics.

[26]  B. Rourke,et al.  Prediction of the reading and spelling performances of normal and retarded readers: A four-year follow-up , 1977, Journal of abnormal child psychology.