The GH–IGF-I axis and breast cancer

[1]  Marcel Garcia,et al.  Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells , 2002, Oncogene.

[2]  F. Speizer,et al.  A sequence repeat in the insulin‐like growth factor‐1 gene and risk of breast cancer , 2002, International journal of cancer.

[3]  E. Eppler,et al.  IGF-I in human breast cancer: low differentiation stage is associated with decreased IGF-I content. , 2002, European journal of endocrinology.

[4]  E. Riboli,et al.  Prospective study of IGF-I, IGF-binding proteins, and breast cancer risk, in Northern and Southern Sweden , 2002, Cancer Causes & Control.

[5]  G. Procopio,et al.  A randomized, multicenter prospective trial assessing long‐acting release octreotide pamoate plus tamoxifen as a first line therapy for advanced breast carcinoma , 2002, Cancer.

[6]  J. Baselga,et al.  Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect. , 2001, Journal of the National Cancer Institute.

[7]  Y. Lu,et al.  Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). , 2001, Journal of the National Cancer Institute.

[8]  J. Bourhis,et al.  Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells , 2001, British Journal of Cancer.

[9]  R. Shi,et al.  Polymorphic CA repeats in the IGF-I gene and breast cancer , 2001, Breast Cancer Research and Treatment.

[10]  S. Andò,et al.  IGF-I Receptor-induced Cell-Cell Adhesion of MCF-7 Breast Cancer Cells Requires the Expression of Junction Protein ZO-1* , 2001, The Journal of Biological Chemistry.

[11]  A. Leathem,et al.  IGF status is altered by tamoxifen in patients with breast cancer , 2001, Molecular pathology : MP.

[12]  A. Schally,et al.  Antagonists of GHRH decrease production of GH and IGF-I in MXT mouse mammary cancers and inhibit tumor growth. , 2001, Endocrinology.

[13]  M. Cazzaniga,et al.  Effect of low dose tamoxifen on the insulin-like growth factor system in healthy women , 2001, Breast Cancer Research and Treatment.

[14]  K. Friend Cancer and the potential place for growth hormone receptor antagonist therapy. , 2001, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[15]  S. Safe,et al.  Activation of adenosine deaminase in MCF-7 cells through IGF-estrogen receptor alpha crosstalk. , 2001, Journal of molecular endocrinology.

[16]  L. Kindblom,et al.  Growth hormone receptor is expressed in human breast cancer. , 2001, The American journal of pathology.

[17]  M. Papotti,et al.  Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines. , 2001, The Journal of clinical endocrinology and metabolism.

[18]  P. Elizalde,et al.  Activation of ErbB-2 via a hierarchical interaction between ErbB-2 and type I insulin-like growth factor receptor in mammary tumor cells , 2001, Oncogene.

[19]  W. Cohick,et al.  Insulin-Like Growth Factor I (IGF-I) and Cyclic Adenosine 3',5'-Monophosphate Regulate IGF-Binding Protein-3 Gene Expression by Transcriptional and Posttranscriptional Mechanisms in Mammary Epithelial Cells* *This work was supported by the USDA (Award 98-35026-6428 to W.S.C.), the New Jersey Agricul , 2000, Endocrinology.

[20]  J. Farndon,et al.  Insulin‐like growth factor binding protein‐3 (IGFBP‐3) potentiates paclitaxel‐induced apoptosis in human breast cancer cells , 2000, International journal of cancer.

[21]  A. Schally,et al.  Isolation and sequencing of cDNAs for splice variants of growth hormone-releasing hormone receptors from human cancers. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[22]  M. Martin,et al.  Regulation of estrogen receptor-alpha gene expression by epidermal growth factor. , 2000, The Journal of endocrinology.

[23]  R. Nicholson,et al.  Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer , 2000, British Journal of Cancer.

[24]  Alon Chen,et al.  Selective Expression of Neuropeptides in the Rat Mammary Gland: Somatostatin Gene Is Expressed During Lactation1. , 1999, Endocrinology.

[25]  S. Heffelfinger,et al.  Angiogenic growth factors in preinvasive breast disease. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[26]  D. Yee,et al.  Insulin‐like growth factor (IGF)‐I rescues breast cancer cells from chemotherapy‐induced cell death – proliferative and anti‐apoptotic effects , 1999, Breast Cancer Research and Treatment.

[27]  R. Glazer,et al.  Role of AKT1 in 17β-estradiol- and insulin-like growth factor I (IGF-I)-dependent proliferation and prevention of apoptosis in MCF-7 breast carcinoma cells , 1999 .

[28]  S. Hilsenbeck,et al.  Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. , 1999, Molecular endocrinology.

[29]  L. Hartmann,et al.  A randomized trial of tamoxifen alone or combined with octreotide in the treatment of women with metastatic breast carcinoma , 1999, Cancer.

[30]  N. Dobbs,et al.  Phase II study of RC-160 (vapreotide), an octapeptide analogue of somatostatin, in the treatment of metastatic breast cancer , 1999, British Journal of Cancer.

[31]  R. Kineman,et al.  Expression of growth hormone-releasing hormone (GHRH) messenger ribonucleic acid and the presence of biologically active GHRH in human breast, endometrial, and ovarian cancers. , 1999, The Journal of clinical endocrinology and metabolism.

[32]  Sandra,et al.  A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. , 1998, Cancer research.

[33]  David J Hunter,et al.  Circulating concentrations of insulin-like growth factor I and risk of breast cancer , 1998, The Lancet.

[34]  M. Waters,et al.  Cellular expression of growth hormone and prolactin receptors in human breast disorders , 1998, International journal of cancer.

[35]  N. Webster,et al.  Elevated insulin-like growth factor I receptor autophosphorylation and kinase activity in human breast cancer. , 1998, Cancer research.

[36]  L. Sciacca,et al.  Type I insulin-like growth factor receptor function in breast cancer , 1998, Breast Cancer Research and Treatment.

[37]  D. Leroith,et al.  Growth hormone treatment induces mammary gland hyperplasia in aging primates , 1997, Nature Medicine.

[38]  E. Surmacz,et al.  Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cells. , 1997, Cancer research.

[39]  G. Mengod,et al.  Somatostatin receptor subtypes sst1, sst2, sst3 and sst5expression in human pituitary, gastroentero‐pancreatic and mammary tumors , 1997 .

[40]  P. Fontanaud,et al.  Somatostatin and growth hormone-releasing hormone in normal and tumoral human breast tissue: endogenous content, in vitro pulsatile release, and regulation. , 1997, The Journal of clinical endocrinology and metabolism.

[41]  H. Huynh,et al.  Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation. , 1996, Cancer research.

[42]  P. Bontempo,et al.  Tyrosine kinase/p21ras/MAP‐kinase pathway activation by estradiol‐receptor complex in MCF‐7 cells. , 1996, The EMBO journal.

[43]  D. Hill,et al.  Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II) , 1995, British Journal of Cancer.

[44]  C. Roberts,et al.  Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid. , 1995, Endocrinology.

[45]  M. Blankenstein,et al.  Expression of the gene encoding growth hormone in the human mammary gland. , 1995, The Journal of clinical endocrinology and metabolism.

[46]  R. Wieczorek,et al.  Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid. , 1995, Endocrinology.

[47]  R. Rosenfeld,et al.  Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells. , 1993, The Journal of biological chemistry.

[48]  W. McGuire,et al.  Expression of insulin‐like growth factor binding proteins in human breast cancer correlates with estrogen receptor status , 1993, Journal of cellular biochemistry.

[49]  H. Huynh,et al.  In vivo inhibition of insulin-like growth factor I gene expression by tamoxifen. , 1993, Cancer research.

[50]  V. Ilvesmäki,et al.  Insulin-like growth factor binding proteins in human breast cancer tissue. , 1992, Cancer research.

[51]  C. Bruns,et al.  Preclinical studies on the anticancer activity of the somatostatin analogue octreotide (SMS 201-995). , 1992, Metabolism: clinical and experimental.

[52]  B. Carlsson,et al.  High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice , 1992, The Journal of Steroid Biochemistry and Molecular Biology.

[53]  J. Peyrat,et al.  Insulin-like growth factor 1 receptors in human breast tumour: localisation and quantification by histo-autoradiographic analysis. , 1992, British Journal of Cancer.

[54]  M. Pollak,et al.  Tamoxifen attenuates pulsatile growth hormone secretion: mediation in part by somatostatin. , 1992, Endocrinology.

[55]  J. Bonneterre,et al.  Insulin-like growth factor 1 receptors (IGF1-R) and IGF1 in human breast tumors , 1990, The Journal of Steroid Biochemistry and Molecular Biology.

[56]  M. Johnson,et al.  Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells. , 1990, The Journal of biological chemistry.

[57]  C. Osborne,et al.  Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. , 1989, The Journal of clinical investigation.

[58]  D. Yee,et al.  Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. , 1989, Molecular endocrinology.

[59]  S. Paik Expression of IGF-I and IGF-II mRNA in breast tissue , 2005, Breast Cancer Research and Treatment.

[60]  M. Ellis,et al.  Insulin-like growth factor mediated stromal-epithelial interactions in human breast cancer , 2004, Breast Cancer Research and Treatment.

[61]  L. Lai,et al.  EFFECT OF TRANSFORMING GROWTH FACTOR‐ β 1, INSULIN‐LIKE GROWTH FACTOR‐I AND INSULIN‐LIKE GROWTH FACTOR‐II ON CELL GROWTH AND OESTROGEN METABOLISM IN HUMAN BREAST CANCER CELL LINES , 2001 .

[62]  W. Ruan,et al.  Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development. , 1999, Endocrinology.

[63]  T. Crook,et al.  Analysis of somatostatin receptor subtype mRNA expression in human breast cancer. , 1997, British Journal of Cancer.

[64]  D. Yee,et al.  Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells. , 1997, The Journal of endocrinology.

[65]  P. Lønning,et al.  Insulin-like growth factors in breast cancer. , 1996, Acta oncologica.

[66]  J. Rosen,et al.  Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression. , 1996, Endocrinology.

[67]  H. Rochefort Oestrogens, proteases and breast cancer. From cell lines to clinical applications. , 1994, European journal of cancer.

[68]  D. Yee,et al.  Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells. , 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[69]  J. Bonneterre,et al.  Plasma insulin-like growth factor-1 (IGF-1) concentrations in human breast cancer. , 1993, European journal of cancer.