A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver.
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Jorgen W. Nelson | D. Baker | R. Gottardo | N. King | M. Pancera | Jorgen W Nelson | R. Sauerwein | A. Schön | R. Seder | R. Amino | A. Molina-Cruz | C. Barillas-Mury | B. Flynn | Y. Flores-Garcia | F. Zavala | J. Francica | R. Mason | I. Cockburn | R. Vistein | B. Mayer | A. H. Idris | Lawrence T. Wang | Lais S. Pereira | Marlon Dillon | A. Fabra-García | J. O'Connor | Annie S. P. Yang | N. Hurlburt | Neville K Kisalu | Nicole Cavett | Monica Gerber | Reid Ballard | D. Baker | D. Baker | Rachel Vistein | Alvaro Molina-Cruz | Azza H. Idris | Monica W. Gerber
[1] A. Bradley,et al. Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein , 2020, PLoS pathogens.
[2] R. Gottardo,et al. Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein , 2020, Malaria Journal.
[3] C. King,et al. Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages , 2019, Malaria Journal.
[4] Kohske Takahashi,et al. Welcome to the Tidyverse , 2019, J. Open Source Softw..
[5] H. Wardemann,et al. Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs , 2019, Nature Medicine.
[6] H. Wardemann,et al. Antibodies against Plasmodium falciparum malaria at the molecular level , 2019, Nature Reviews Immunology.
[7] P. Sinnis,et al. Antibody-Mediated Protection against Plasmodium Sporozoites Begins at the Dermal Inoculation Site , 2018, mBio.
[8] S. Thiberge,et al. Cytotoxic anti-circumsporozoite antibodies target malaria sporozoites in the host skin , 2018, Nature Microbiology.
[9] R. Seder,et al. Malaria prevention: from immunological concepts to effective vaccines and protective antibodies , 2018, Nature Immunology.
[10] I. Wilson,et al. Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts , 2018, Science Advances.
[11] S. Hoffman,et al. Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope , 2018, Science.
[12] J. Julien,et al. Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies. , 2018, Immunity.
[13] Erika L. Flannery,et al. Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo , 2018, Front. Immunol..
[14] S. Hoffman,et al. A public antibody lineage that potently inhibits malaria infection by dual binding to the circumsporozoite protein , 2018, Nature Medicine.
[15] Alex B. Miller,et al. A human monoclonal antibody prevents malaria infection and defines a new site of vulnerability on Plasmodium falciparum circumsporozoite protein , 2018, Nature Medicine.
[16] S. Hoffman,et al. Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection , 2018, The Journal of experimental medicine.
[17] S. Kappe,et al. Natural Parasite Exposure Induces Protective Human Anti‐Malarial Antibodies , 2017, Immunity.
[18] C. Janse,et al. An in vitro assay to measure antibody-mediated inhibition of P. berghei sporozoite invasion against P. falciparum antigens , 2017, Scientific Reports.
[19] I. Wilson,et al. Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein , 2017, Proceedings of the National Academy of Sciences.
[20] Lu Zhang,et al. Massively parallel de novo protein design for targeted therapeutics , 2017, Nature.
[21] P. V. van Genderen,et al. Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers , 2017, Science Translational Medicine.
[22] F. Frischknecht,et al. Plasmodium Sporozoite Biology. , 2017, Cold Spring Harbor perspectives in medicine.
[23] D. Christensen,et al. Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection , 2017, npj Vaccines.
[24] D. Christensen,et al. Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection , 2017, npj Vaccines.
[25] J. Whisstock,et al. Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice. , 2017, Cell reports.
[26] V. V. Ganusov,et al. Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids , 2017, Science Immunology.
[27] Mario Roederer,et al. Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection , 2017, Proceedings of the National Academy of Sciences.
[28] C. Wilke. Streamlined Plot Theme and Plot Annotations for 'ggplot2' , 2015 .
[29] Kwaku Poku Asante,et al. Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial , 2015 .
[30] Yuming Guo,et al. The effect of air pollution on human physiological function in China: a longitudinal study , 2015, The Lancet.
[31] Lirong Shi,et al. Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies. , 2015, The Journal of infectious diseases.
[32] S. C. T. P. Rts. Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial , 2015, The Lancet.
[33] Peter G. Kremsner,et al. Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. , 2015 .
[34] Kwaku Poku Asante,et al. A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine , 2014, BMC Medicine.
[35] D. Bates,et al. Fitting Linear Mixed-Effects Models Using lme4 , 2014, 1406.5823.
[36] G. van Gemert,et al. Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice , 2013, Malaria Journal.
[37] Mario Roederer,et al. Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine , 2013, Science.
[38] S. Thiberge,et al. Role of host cell traversal by the malaria sporozoite during liver infection , 2013, The Journal of experimental medicine.
[39] Kwaku Poku Asante,et al. Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data , 2013, The Lancet. Infectious diseases.
[40] A. Vaughan,et al. A rapid and scalable density gradient purification method for Plasmodium sporozoites , 2012, Malaria Journal.
[41] M. Hollingshead,et al. Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts , 2011, BMC biotechnology.
[42] K. Marsh,et al. Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial , 2011, The Lancet. Infectious diseases.
[43] David Firth,et al. Bias reduction in exponential family nonlinear models , 2009 .
[44] V. A. Stewart,et al. Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection. , 2009, The Journal of infectious diseases.
[45] A. Jin,et al. Structure of the Plasmodium falciparum Circumsporozoite Protein, a Leading Malaria Vaccine Candidate* , 2009, The Journal of Biological Chemistry.
[46] Kurt Hornik,et al. Implementing a Class of Permutation Tests: The coin Package , 2008 .
[47] M. Prevost,et al. Host cell traversal is important for progression of the malaria parasite through the dermis to the liver. , 2008, Cell host & microbe.
[48] C. Pipper,et al. [''R"--project for statistical computing]. , 2008, Ugeskrift for laeger.
[49] John A. Robinson,et al. Crystal structure of an NPNA-repeat motif from the circumsporozoite protein of the malaria parasite Plasmodium falciparum. , 2006, Chemical communications.
[50] J. Sattabongkot,et al. Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax. , 2006, The American journal of tropical medicine and hygiene.
[51] U. Frevert,et al. Intravital microscopy demonstrating antibody-mediated immobilisation of Plasmodium berghei sporozoites injected into skin by mosquitoes. , 2004, International journal for parasitology.
[52] M. Sällberg,et al. A Malaria Vaccine Candidate Based on a Hepatitis B Virus Core Platform , 2003, Intervirology.
[53] A. Holder,et al. Function of Region I and II Adhesive Motifs ofPlasmodium falciparum Circumsporozoite Protein in Sporozoite Motility and Infectivity* , 2002, The Journal of Biological Chemistry.
[54] L. Miller,et al. Malaria: A sporozoite runs through it , 2001, Current Biology.
[55] M. Mota,et al. Migration of Plasmodium sporozoites through cells before infection. , 2001, Science.
[56] J. Vanderberg,et al. Delayed migration of Plasmodium sporozoites from the mosquito bite site to the blood. , 1997, The American journal of tropical medicine and hygiene.
[57] Joe D. Cohen,et al. A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group. , 1997, The New England journal of medicine.
[58] V. Nussenzweig,et al. The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of plasmodium falciparum sporozoites , 1992, Cell.
[59] R. Lerner,et al. Conformational preferences of synthetic peptides derived from the immunodominant site of the circumsporozoite protein of Plasmodium falciparum by 1H NMR. , 1990, Biochemistry.
[60] J. Verhave,et al. The biotin‐streptavidin system in a two‐site ELISA for the detection of plasmodial sporozoite antigen in mosquitoes , 1988, Parasite immunology.
[61] V. Nussenzweig,et al. Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes , 1983, The Journal of experimental medicine.
[62] J. Vanderberg,et al. Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei , 1967, Nature.
[63] G. Andrew,et al. arm: Data Analysis Using Regression and Multilevel/Hierarchical Models , 2014 .
[64] H. Delemarre-van de Waal,et al. [A 2d patient with tropical malaria contracted in a natural way in the Netherlands]. , 1981, Nederlands tijdschrift voor geneeskunde.
[65] S. Holm. A Simple Sequentially Rejective Multiple Test Procedure , 1979 .
[66] J. Vanderberg,et al. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. V. In vitro effects of immune serum on sporozoites. , 1969, Military medicine.