Integrative inflammasome activity in the regulation of intestinal mucosal immune responses
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[1] H. Okamura,et al. IL18 polymorphism is associated with an increased risk of Crohn’s disease , 2002, Journal of Gastroenterology.
[2] L. Peyrin-Biroulet,et al. Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. , 2012, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[3] H. Herfarth,et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. , 2012, Immunity.
[4] B. Finlay,et al. Role of Inflammasomes in Host Defense against Citrobacter rodentium Infection* , 2012, The Journal of Biological Chemistry.
[5] Moshe Arditi,et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. , 2012, Immunity.
[6] E. Elinav,et al. Inflammasomes: far beyond inflammation , 2012, Nature Immunology.
[7] G. Núñez,et al. Sensing and reacting to microbes through the inflammasomes , 2012, Nature Immunology.
[8] R. Vance,et al. Lethal inflammasome activation by a multi-drug resistant pathobiont upon antibiotic disruption of the microbiota , 2012, Nature Medicine.
[9] G. Núñez,et al. NLRC4-driven interleukin-1β production discriminates between pathogenic and commensal bacteria and promotes host intestinal defense , 2012, Nature Immunology.
[10] Richard A. Flavell,et al. Inflammasomes in health and disease , 2012, Nature.
[11] Richard A. Flavell,et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity , 2012, Nature.
[12] P. Hylemon,et al. Linkage of gut microbiome with cognition in hepatic encephalopathy. , 2012, American journal of physiology. Gastrointestinal and liver physiology.
[13] D. Green,et al. The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. , 2011, Cancer cell.
[14] Jinfeng Liu,et al. Non-canonical inflammasome activation targets caspase-11 , 2011, Nature.
[15] Hao Xu,et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus , 2011, Nature.
[16] R. Vance,et al. Innate immune recognition of bacterial ligands by NAIPs dictates inflammasome specificity , 2011, Nature.
[17] Richard A Flavell,et al. Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation , 2011, Cell cycle.
[18] J. Bertin,et al. A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis , 2011, The Journal of Immunology.
[19] F. Bredin,et al. Genetic association between NLRP3 variants and Crohn's disease does not replicate in a large UK panel , 2011, Inflammatory bowel diseases.
[20] Yan Li,et al. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis , 2011, Inflammatory bowel diseases.
[21] Richard A. Flavell,et al. NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis , 2011, Cell.
[22] B. Chandran,et al. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection. , 2011, Cell host & microbe.
[23] M. Chamaillard,et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury , 2011, Proceedings of the National Academy of Sciences.
[24] Sky W. Brubaker,et al. Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome , 2011, Infection and Immunity.
[25] E. Elinav,et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4 , 2010, Proceedings of the National Academy of Sciences.
[26] A. Aderem,et al. Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria , 2010, Nature Immunology.
[27] M. Lamkanfi,et al. IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation , 2010, The Journal of Immunology.
[28] F. Marincola,et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18 , 2010, The Journal of experimental medicine.
[29] V. Dixit,et al. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella , 2010, The Journal of experimental medicine.
[30] H. Herfarth,et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer , 2010, The Journal of experimental medicine.
[31] J. Tschopp,et al. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome , 2010, Gut.
[32] Jongdae Lee,et al. ERK activation drives intestinal tumorigenesis in Apcmin/+ mice , 2010, Nature Medicine.
[33] N. Beauchemin,et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. , 2010, Immunity.
[34] M. Kastan,et al. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. , 2010, Immunity.
[35] B. Siegmund. Interleukin-18 in intestinal inflammation: friend and foe? , 2010, Immunity.
[36] Richard Bonneau,et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome , 2010, Proceedings of the National Academy of Sciences.
[37] J. Tschopp,et al. Thioredoxin-interacting protein links oxidative stress to inflammasome activation , 2010, Nature Immunology.
[38] J. Tschopp,et al. The Inflammasomes , 2010, Cell.
[39] M. Heikenwalder,et al. The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation. , 2009, Cell host & microbe.
[40] Jasmyn A. Dunn,et al. HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA , 2009, Science.
[41] M. Karin,et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. , 2009, Cancer cell.
[42] Ozge Canli,et al. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. , 2009, Cancer cell.
[43] E. Alnemri,et al. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA , 2009, Nature.
[44] Daniel R. Caffrey,et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC , 2009, Nature.
[45] Charles Giardina,et al. Mouse models for the study of colon carcinogenesis. , 2008, Carcinogenesis.
[46] Mathieu Lemire,et al. Common variants in the NLRP3 region contribute to Crohn's disease susceptibility , 2009, Nature Genetics.
[47] Sky W. Brubaker,et al. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin , 2008, Nature Immunology.
[48] M Ojima,et al. Relationship of Porphyromonas gingivalis with glycemic level in patients with type 2 diabetes following periodontal treatment. , 2008, Oral microbiology and immunology.
[49] K. Rock,et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.
[50] V. Nizet,et al. A Nod2–nalp1 Complex Mediates Caspase-1-dependent Il-1 Secretion in Response to Bacillus Anthracis Infection and Muramyl Dipeptide Nod2, a Nod-like Receptor (nlr), Is an Intracellular Sensor of Bacterial Muramyl Dipeptide (mdp) That Was Suggested to Promote Secretion of the Proinflammatory Cytokine , 2022 .
[51] A. Zhernakova,et al. Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. , 2008, American journal of human genetics.
[52] N. Mukaida,et al. Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. , 2008, The Journal of clinical investigation.
[53] F. Schmidt. Meta-Analysis , 2008 .
[54] C. Sasakawa,et al. Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages , 2007, PLoS pathogens.
[55] R. Medzhitov,et al. Regulation of Spontaneous Intestinal Tumorigenesis Through the Adaptor Protein MyD88 , 2007, Science.
[56] H. Lehr,et al. The ICE Inhibitor Pralnacasan Prevents DSS-Induced Colitis in C57BL/6 Mice and Suppresses IP-10 mRNA but Not TNF-α mRNA Expression , 2007, Digestive Diseases and Sciences.
[57] J. Ting,et al. Cutting Edge: Monarch-1 Suppresses Non-Canonical NF-κB Activation and p52-Dependent Chemokine Expression in Monocytes1 , 2007, The Journal of Immunology.
[58] J. Ting,et al. Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. , 2007, Journal of immunology.
[59] A. Zychlinsky,et al. Caspase-1-Mediated Activation of Interleukin-1β (IL-1β) and IL-18 Contributes to Innate Immune Defenses against Salmonella enterica Serovar Typhimurium Infection , 2006, Infection and Immunity.
[60] J. Bertin,et al. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis , 2006, The Journal of experimental medicine.
[61] J. Bertin,et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages , 2006, Nature Immunology.
[62] J. Bertin,et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. , 2006, Immunity.
[63] T. Tomita,et al. Association Between Il‐18 Gene Promoter Polymorphisms and Inflammatory Bowel Disease in a Japanese Population , 2005, Inflammatory bowel diseases.
[64] T. Sørensen,et al. Increased Risk of Intestinal Cancer in Crohn's Disease: A Meta-Analysis of Population-Based Cohort Studies , 2005, The American Journal of Gastroenterology.
[65] Stefan Wirtz,et al. TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling , 2004 .
[66] R. Kiesslich,et al. TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. , 2004, Immunity.
[67] Michael Karin,et al. IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer , 2004, Cell.
[68] Ruslan Medzhitov,et al. Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis , 2004, Cell.
[69] H. Lehr,et al. The Interleukin-1β-Converting Enzyme Inhibitor Pralnacasan Reduces Dextran Sulfate Sodium-Induced Murine Colitis and T Helper 1 T-Cell Activation , 2004, Journal of Pharmacology and Experimental Therapeutics.
[70] H. Lehr,et al. The interleukin-1 beta-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation. , 2004, The Journal of pharmacology and experimental therapeutics.
[71] S. Akira,et al. Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice. , 2003, Scandinavian journal of gastroenterology.
[72] T. Hibi,et al. Interleukin‐18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin‐18 transgenic mice , 2003, Journal of gastroenterology and hepatology.
[73] J. Bertin,et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF‐κB and caspase‐1 , 2002, FEBS letters.
[74] F. Martinon,et al. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. , 2002, Molecular cell.
[75] M. Neurath,et al. Treatment of T Cell-Dependent Experimental Colitis in SCID Mice by Local Administration of an Adenovirus Expressing IL-18 Antisense mRNA1 , 2002, The Journal of Immunology.
[76] G. Fantuzzi,et al. IL-1β-converting enzyme (caspase-1) in intestinal inflammation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[77] S. Akira,et al. Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease. , 2001, Gastroenterology.
[78] G. Fantuzzi,et al. Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-γ and TNF-α production , 2001 .
[79] K. Abrams,et al. The risk of colorectal cancer in ulcerative colitis: a meta-analysis , 2001, Gut.
[80] G. Fantuzzi,et al. Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-gamma and TNF-alpha production. , 2001, American journal of physiology. Regulatory, integrative and comparative physiology.
[81] G. Fantuzzi,et al. IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[82] T. Hibi,et al. Interleukin 18 is a potent proliferative factor for intestinal mucosal lymphocytes in Crohn's disease. , 2000, Gastroenterology.
[83] C. Moskaluk,et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. , 1998, Journal of immunology.
[84] A. Moser,et al. Intestinal neoplasia in the ApcMin mouse: independence from the microbial and natural killer (beige locus) status. , 1997, Cancer research.
[85] John Saunders,et al. Friend and Foe , 1890, The Hospital.