Direct-to-consumer pharmacogenomic testing.

1367 ISSN 1462-2416 10.2217/PGS.11.100 © 2011 Future Medicine Ltd Pharmacogenomics (2011) 12(10), 1367–1370 “Although PGx testing may very well one day fulfill its promise of preventing serious consequences of adverse drug reactions as well as avoiding the costs of giving certain drugs to patients who are probably nonresponders, we caution against the premature translation of such tests directly to the public.”

[1]  Kelly Fryer-Edwards,et al.  The Ethical Challenges of Direct-to-Consumer Genetic Testing , 2007 .

[2]  W. Burke,et al.  Pharmacogenetic testing: not as simple as it seems , 2008, Genetics in Medicine.

[3]  P. Borry,et al.  Personal Genome Testing: Do You Know What You Are Buying? , 2009, The American journal of bioethics : AJOB.

[4]  J. Fullerton,et al.  Predictive and diagnostic genetic testing in psychiatry. , 2010, The Psychiatric clinics of North America.

[5]  Amy L. McGuire,et al.  An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commons. , 2008, JAMA.

[6]  Tao Wang,et al.  Social Networkers' Attitudes Toward Direct-to-Consumer Personal Genome Testing , 2009, The American journal of bioethics : AJOB.

[7]  Pascal Borry,et al.  Is there a doctor in the house? , 2011, Journal of Community Genetics.

[8]  B. Wilfond,et al.  Ethical and clinical practice considerations for genetic counselors related to direct‐to‐consumer marketing of genetic tests , 2006, American journal of medical genetics. Part C, Seminars in medical genetics.

[9]  Muin J Khoury,et al.  A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. , 2008, American journal of human genetics.

[10]  D. Avard,et al.  Are the kids really all right? Direct-to-consumer genetic testing in children: are company policies clashing with professional norms? , 2011, European Journal of Human Genetics.

[11]  C. Møldrup.  Ethical, Social and Legal Implications of Pharmacogenomics: A Critical Review , 2002, Public Health Genomics.

[12]  Pascal Borry,et al.  Where are you going, where have you been: a recent history of the direct-to-consumer genetic testing market , 2010, Journal of Community Genetics.

[13]  Raluca Mihaescu,et al.  Evaluation of risk prediction updates from commercial genome-wide scans , 2009, Genetics in Medicine.

[14]  Gail Javitt,et al.  The current landscape for direct-to-consumer genetic testing: legal, ethical, and policy issues. , 2008, Annual review of genomics and human genetics.

[15]  Pascal Borry,et al.  Statement of the ESHG on direct-to-consumer genetic testing for health-related purposes , 2010, European Journal of Human Genetics.

[16]  Richard R Sharp,et al.  Evaluating the utility of personal genomic information , 2009, Genetics in Medicine.

[17]  H. Wallace.  Most gene test sales are misleading , 2008, Nature Biotechnology.