Safety and tolerability of 6-month supplementation with a vitamin D, calcium and leucine-enriched whey protein medical nutrition drink in sarcopenic older adults

[1]  L. Donini,et al.  Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: the PROVIDE study , 2019, Aging Clinical and Experimental Research.

[2]  K. Dretakis,et al.  The role of parathyroid hormone (PTH) and vitamin D in falls and hip fracture type , 2019, Aging Clinical and Experimental Research.

[3]  G. Sergi,et al.  Dietary strategies for mitigating osteosarcopenia in older adults: a narrative review , 2019, Aging Clinical and Experimental Research.

[4]  Stuart M Phillips,et al.  Changes in Kidney Function Do Not Differ between Healthy Adults Consuming Higher- Compared with Lower- or Normal-Protein Diets: A Systematic Review and Meta-Analysis , 2018, The Journal of nutrition.

[5]  L. D. de Groot,et al.  The association between 25-hydroxyvitamin D concentration, physical performance and frailty status in older adults , 2018, European Journal of Nutrition.

[6]  J. Martínez,et al.  Higher Protein Intake Is Not Associated with Decreased Kidney Function in Pre-Diabetic Older Adults Following a One-Year Intervention—A Preview Sub-Study , 2018, Nutrients.

[7]  S. Walrand,et al.  Vitamin D supplementation restores the blunted muscle protein synthesis response in deficient old rats through an impact on ectopic fat deposition. , 2017, The Journal of nutritional biochemistry.

[8]  M. Drey,et al.  Nutrition, frailty, and sarcopenia , 2017, Aging Clinical and Experimental Research.

[9]  R. Kumar,et al.  Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment. , 2016, Endocrine reviews.

[10]  H. van Loveren,et al.  Dietary reference values for vitamin K , 2016, EFSA journal. European Food Safety Authority.

[11]  R. Elango,et al.  Determination of the safety of leucine supplementation in healthy elderly men , 2016, Amino Acids.

[12]  D. Fouque,et al.  Gastro-intestinal tolerance and renal safety of protein oral nutritional supplements in nursing home residents: A randomized controlled trial , 2016, The journal of nutrition, health & aging.

[13]  L. Donini,et al.  Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial. , 2015, Journal of the American Medical Directors Association.

[14]  L. D. de Groot,et al.  Macronutrient Intake and Inadequacies of Community-Dwelling Older Adults, a Systematic Review , 2015, Annals of Nutrition and Metabolism.

[15]  S. Minisola,et al.  The diagnosis and management of hypercalcaemia , 2015, BMJ : British Medical Journal.

[16]  L. D. de Groot,et al.  Micronutrient intakes and potential inadequacies of community-dwelling older adults: a systematic review , 2015, British Journal of Nutrition.

[17]  M. Petzold,et al.  Seasonal variations in serum 25-hydroxy vitamin D levels in a Swedish cohort , 2015, Endocrine.

[18]  K. Nair,et al.  Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group. , 2014, Clinical nutrition.

[19]  Lynette M. Smith,et al.  Incidence of hypercalciuria and hypercalcemia during vitamin D and calcium supplementation in older women , 2014, Menopause.

[20]  C. Cooper,et al.  The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: a consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). , 2014, Maturitas.

[21]  L. Schwingshackl,et al.  Comparison of High vs. Normal/Low Protein Diets on Renal Function in Subjects without Chronic Kidney Disease: A Systematic Review and Meta-Analysis , 2014, PloS one.

[22]  S. Walrand,et al.  1,25(OH)2-vitamin D3 enhances the stimulating effect of leucine and insulin on protein synthesis rate through Akt/PKB and mTOR mediated pathways in murine C2C12 skeletal myotubes. , 2013, Molecular nutrition & food research.

[23]  H. Bischoff-Ferrari,et al.  A randomized study on the effect of vitamin D₃ supplementation on skeletal muscle morphology and vitamin D receptor concentration in older women. , 2013, The Journal of clinical endocrinology and metabolism.

[24]  M. Cesari,et al.  Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. , 2013, Journal of the American Medical Directors Association.

[25]  R. Ball,et al.  Determination of the tolerable upper intake level of leucine in adult men. , 2012, The Journal of nutrition.

[26]  A. Renwick,et al.  A proposal for an upper limit of leucine safe intake in healthy adults. , 2012, The Journal of nutrition.

[27]  Efsa Panel on Dietetic Products Scientific Opinion on the Tolerable Upper Intake Level of vitamin D , 2012 .

[28]  Efsa Panel on Dietetic Products Scientific opinion on the Tolerable Upper Intake Level of calcium. , 2012 .

[29]  W. Willett,et al.  A pooled analysis of vitamin D dose requirements for fracture prevention. , 2012, The New England journal of medicine.

[30]  H. Bischoff-Ferrari Vitamin D and fracture prevention. , 2012, Rheumatic diseases clinics of North America.

[31]  L. Mosoni,et al.  Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance. , 2011, The Journal of nutritional biochemistry.

[32]  JoAnn E. Manson,et al.  The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know , 2010, The Journal of clinical endocrinology and metabolism.

[33]  J. Coad,et al.  Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient – a randomised, placebo-controlled trial , 2009, British Journal of Nutrition.

[34]  C. Schmid,et al.  A new equation to estimate glomerular filtration rate. , 2009, Annals of internal medicine.

[35]  R. Hayes,et al.  Serum vitamin D and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian screening trial. , 2009, Cancer research.

[36]  R. Stolzenberg-Solomon Vitamin D and pancreatic cancer. , 2009, Annals of epidemiology.

[37]  M. James,et al.  Derivation and internal validation of an equation for albumin-adjusted calcium , 2008, BMC clinical pathology.

[38]  M. Holick,et al.  Vitamin D and Skin Physiology: A D‐Lightful Story , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[39]  David Moher,et al.  Effectiveness and safety of vitamin D in relation to bone health. , 2007, Evidence report/technology assessment.

[40]  P. Elliott,et al.  Association between protein intake and blood pressure: the INTERMAP Study. , 2006, Archives of internal medicine.

[41]  Marjolein Visser,et al.  Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. , 2003, The Journal of clinical endocrinology and metabolism.

[42]  A. Frølich Prevalence of hypercalcaemia in normal and in hospital populations. , 1998, Danish medical bulletin.

[43]  B. Winblad,et al.  Levels of serum creatinine and estimated creatinine clearance over the age of 75: a study of an elderly Swedish population. , 1996, Archives of gerontology and geriatrics.

[44]  L. Bouter,et al.  Falls in the elderly: a prospective study of risk factors and risk profiles. , 1996, American journal of epidemiology.

[45]  P. Marckmann,et al.  High-protein diets and renal health. , 2015, Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.

[46]  Efsa Publication EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the Tolerable Upper Intake Level of vitamin D , 2012 .

[47]  Intakes for Calcium , Phosphorus , Magnesium , Vitamin D , and Fluoride , 1974 .