Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis

Facial, trigeminal, and hypoglossal motoneuron involvement was quantified in 25 amyotrophic lateral sclerosis patients and in normal controls. Measures included (1) maximum voluntary contraction of the lower lip, mandible, and tongue using custom-designed force transducers, (2) clinical functions of each muscle group, and in some patients (3) orofacial mobility using videofluoroscopy. All measures indicated that the tongue muscles were most severely affected, even in patients who initially had symptoms in the extremities.

[1]  T. Lawyer,et al.  AMYOTROPHIC LATERAL SCLEROSIS: A Clinicoanatomic Study of Fifty-Three Cases , 1953 .

[2]  F. Norris,et al.  The administration of guanidine in amyotrophic lateral sclerosis , 1974, Neurology.

[3]  J. Abbs,et al.  Orofacial fine motor control impairments in congenital spasticity , 1984, Neurology.

[4]  J. Dworkin.  Tongue strength measurement in patients with amyotrophic lateral sclerosis: qualitative vs quantitative procedures. , 1980, Archives of physical medicine and rehabilitation.

[5]  Kenneth M. Heilman,et al.  Directional hypokinesia , 1985, Neurology.

[6]  Dr. Juhani Hyvärinen.  The Parietal Cortex of Monkey and Man , 1982, Studies of Brain Function.

[7]  B. Frame,et al.  Nystagmus in motor neuron disease: Clinicopathological study of two cases , 1984, Annals of neurology.

[8]  R. Bálint.  Seelenlähmung des “Schauens”, optische Ataxie, räumliche Störung der Aufmerksamkeit. pp. 67–81 , 1909 .

[9]  G Holmes,et al.  DISTURBANCES OF VISUAL ORIENTATION , 1918, The British journal of ophthalmology.

[10]  W. Skrandies,et al.  The standing potential of the human eye reflects differences between upper and lower retinal areas , 1986, Vision Research.

[11]  J. C. Sterk,et al.  Reliability of dynamometry in patients with a neuromuscular disorder. , 1982, Engineering in medicine.

[12]  R. Muller.  Progressive motor neuron disease in adults; a clinical study with special reference to the course of the disease. , 1952, Acta psychiatrica et neurologica Scandinavica.

[13]  M. Swash,et al.  Pattern of involvement in the cervical segments in the early stage of motor neurone disease: A single fibre EMG study , 1982, Acta neurologica Scandinavica.

[14]  A. Luria,et al.  Disorders of "simultaneous perception" in a case of bilateral occipito-parietal brain injury. , 1959, Brain : a journal of neurology.

[15]  K. Heilman,et al.  Mechanisms underlying hemispatial neglect , 1979, Annals of neurology.

[16]  M Sawashima,et al.  Patterns of dysarthric movement in patients with amyotrophic lateral sclerosis and pseudobulbar palsy. , 1982, Folia phoniatrica.

[17]  C. Wiles,et al.  The measurement of muscle strength in patients with peripheral neuromuscular disorders. , 1983, Journal of neurology, neurosurgery, and psychiatry.

[18]  J. Brody,et al.  Epidemiology of motor-neuron diseases. , 1973, The New England journal of medicine.

[19]  P. Enderby,et al.  Frenchay Dysarthria Assessment , 1983 .

[20]  T. Shawker,et al.  Tongue Movement During Speech: A Real‐Time Ultrasound Evaluation , 1984, Journal of clinical ultrasound : JCU.

[21]  A D Rosen,et al.  Amyotrophic lateral sclerosis. Clinical features and prognosis. , 1978, Archives of neurology.

[22]  R. P. Mackay,et al.  Course and Prognosis in Amyotrophic Lateral Sclerosis , 1963 .

[23]  K M Heilman,et al.  Hemispace-visual field interactions in visual extinction. , 1987, Journal of neurology, neurosurgery, and psychiatry.

[24]  K. Boman,et al.  PROGNOSIS OF AMYOTROPHIC LATERAL SCLEROSIS , 1967, Acta neurologica Scandinavica.

[25]  J. de Ajuriaguerra,et al.  Balint's syndrome (psychic paralysis of visual fixation) and its minor forms. , 1954, Brain : a journal of neurology.

[26]  A. Aronson,et al.  Tongue force in normals and in dysarthric patients with amyotrophic lateral sclerosis. , 1980, Journal of speech and hearing research.

[27]  H. R. Tyler,et al.  Abnormalities of Perception with Defective Eye Movements (Bálint's Syndrome) , 1968 .

[28]  G. Holmes,et al.  DISTURBANCES OF SPATIAL ORIENTATION AND VISUAL ATTENTION, WITH LOSS OF STEREOSCOPIC VISION , 1919 .

[29]  M. Swash.  Vulnerability of lower brachial myotomes in motor neurone disease A clinical and single fibre EMG study , 1980, Journal of the Neurological Sciences.

[30]  W Skrandies,et al.  Human contrast sensitivity: regional retinal differences. , 1985, Human neurobiology.