Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role.

[1]  M. Benhamed,et al.  Heme Oxygenase Inhibits Human Airway Smooth Muscle Proliferation via a Bilirubin-dependent Modulation of ERK1/2 Phosphorylation* , 2003, Journal of Biological Chemistry.

[2]  W. Durante Heme oxygenase‐1 in growth control and its clinical application to vascular disease , 2003, Journal of cellular physiology.

[3]  Jun Liu,et al.  Rapamycin Induces Heme Oxygenase-1 in Human Pulmonary Vascular Cells: Implications in the Antiproliferative Response to Rapamycin , 2003, Circulation.

[4]  A. Choi,et al.  Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. , 2002, American journal of respiratory cell and molecular biology.

[5]  W. Durante Carbon monoxide and bile pigments: surprising mediators of vascular function , 2002, Vascular medicine.

[6]  W. Durante,et al.  Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. , 2002, Blood.

[7]  M. Carraway,et al.  Carbon monoxide promotes hypoxic pulmonary vascular remodeling. , 2002, American journal of physiology. Lung cellular and molecular physiology.

[8]  T. Minamino,et al.  Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[9]  J. Mitchell,et al.  Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat , 2001, British journal of pharmacology.

[10]  T. Evans,et al.  Endogenously released endothelin-1 from human pulmonary artery smooth muscle promotes cellular proliferation: relevance to pathogenesis of pulmonary hypertension and vascular remodeling. , 2001, American journal of respiratory cell and molecular biology.

[11]  T. Evans,et al.  Autocrine function of inducible nitric oxide synthase and cyclooxygenase-2 in proliferation of human and rat pulmonary artery smooth-muscle cells: species variation. , 1999, American journal of respiratory cell and molecular biology.

[12]  J. Wanstall,et al.  Inhibition by 1H‐[1,2,4]Oxadiazolo[4,3‐a]quinoxalin‐1‐one (ODQ) of Responses to Nitric Oxide‐donors in Rat Pulmonary Artery: Influence of the Mechanism of Nitric Oxide Generation , 1999, The Journal of pharmacy and pharmacology.

[13]  M. Carraway,et al.  Induction of ferritin and heme oxygenase-1 by endotoxin in the lung. , 1998, American journal of physiology. Lung cellular and molecular physiology.

[14]  Y. Kitamura,et al.  Induction of inducible nitric oxide synthase and heme oxygenase-1 in rat glial cells. , 1998, Life sciences.

[15]  J. Brien,et al.  The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate. , 1997, Canadian journal of physiology and pharmacology.

[16]  H. Seo,et al.  Quinazoline derivatives suppress nitric oxide production by macrophages through inhibition of NOS II gene expression , 1996, FEBS letters.

[17]  S. Snyder,et al.  Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[18]  D. Willis,et al.  Heme oxygenase: A novel target for the modulation of inflammatory response , 1996, Nature Medicine.

[19]  B. Milani,et al.  Carbonyl Derivatives of Chloride-Dimethyl Sulfoxide-Ruthenium(II) Complexes: Synthesis, Structural Characterization, and Reactivity of Ru(CO)x(DMSO)4-xCl2 Complexes (x = 1-3) , 1995 .

[20]  S. Kourembanas,et al.  Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[21]  C. Thiemermann,et al.  Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[22]  J. Mcgrath,et al.  Vasodilating effects of carbon monoxide. , 1988, Drug and chemical toxicology.