Perceived Work Overload and Chronic Worrying Predict Weekend–Weekday Differences in the Cortisol Awakening Response

Objective The cortisol increase after awakening has been shown to be associated with work-related stress. Several studies demonstrated a moderate stability of cortisol awakening responses on subsequent days, suggesting situation-dependent variance. This study tests whether cortisol awakening responses are different on weekdays compared with weekend days and whether such differences may be explained by chronic work overload and worrying. Methods Two hundred nineteen participants took saliva samples immediately after awakening and 30, 45, and 60 minutes later on 6 consecutive days starting on Saturday. Perceived chronic work overload and worrying were assessed by a standardized questionnaire. Results There is a clear weekend–weekday difference in the cortisol response to awakening. This difference is associated with chronic work overload and worry. Independent of sex and weekend–weekday differences in time of awakening and sleep duration, participants who report higher levels of chronic work overload and worrying show a stronger increase and higher mean levels of cortisol after awakening on weekdays, but not on weekend days. Conclusions The weekend–weekday differences in the cortisol awakening response and their association with chronic stress clearly demonstrate that the day of cortisol assessment is crucial in psychoendocrinological stress studies.

[1]  G. Davey,et al.  Beliefs about the consequences of worrying , 1996, Cognitive Therapy and Research.

[2]  C. Kirschbaum,et al.  Free cortisol awakening responses are influenced by awakening time , 2004, Psychoneuroendocrinology.

[3]  B. Kudielka,et al.  Compliance With Saliva Sampling Protocols: Electronic Monitoring Reveals Invalid Cortisol Daytime Profiles in Noncompliant Subjects , 2003, Psychosomatic medicine.

[4]  P. Schulz,et al.  Geschlechtsunterschiede bei stressbezogenen Variablen , 2002 .

[5]  Kenneth D. Belzer,et al.  Social problem solving and trait anxiety as predictors of worry in a college student population , 2002 .

[6]  D. Jacks,et al.  Effect of Exercise at Three Exercise Intensities on Salivary Cortisol , 2002, Journal of strength and conditioning research.

[7]  C. Kirschbauma,et al.  Awakening cortisol responses are influenced by health status and awakening time but not by menstrual cycle phase , 2002 .

[8]  F. Hucklebridge,et al.  Association between time of awakening and diurnal cortisol secretory activity , 2001, Psychoneuroendocrinology.

[9]  C. Ring,et al.  Effects of cold, mental and exercise stress on hemoconcentration: 4-week test-retest reliability , 2001 .

[10]  C. Kirschbaum,et al.  Increases in salivary cortisol on awakening on work and non-work days in men and women from the Whitehall II cohort , 2001 .

[11]  E. F. Colecchia,et al.  Transition from dim to bright light in the morning induces an immediate elevation of cortisol levels. , 2001, The Journal of clinical endocrinology and metabolism.

[12]  T. Meijman,et al.  Cortisol secretion throughout the day, perceptions of the work environment, and negative affect , 2000, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[13]  C. Kirschbaum,et al.  Genetic factors, perceived chronic stress, and the free cortisol response to awakening , 2000, Psychoneuroendocrinology.

[14]  H. Anisman,et al.  A prospective study of neuroendocrine and immune alterations associated with the stress of an oral academic examination among graduate students , 2000, Psychoneuroendocrinology.

[15]  Dirk H. Hellhammer,et al.  The cortisol awakening response - normal values and confounds. , 2000, Noise & health.

[16]  A Steptoe,et al.  Job Strain and Anger Expression Predict Early Morning Elevations in Salivary Cortisol , 2000, Psychosomatic medicine.

[17]  F. Scheer,et al.  Light affects morning salivary cortisol in humans. , 1999, The Journal of clinical endocrinology and metabolism.

[18]  I. Goldstein,et al.  Ambulatory blood pressure, heart rate, and neuroendocrine responses in women nurses during work and off work days. , 1999, Psychosomatic medicine.

[19]  C. Kirschbaum,et al.  The cortisol response to awakening in relation to different challenge tests and a 12-hour cortisol rhythm. , 1999, Life sciences.

[20]  C. Kirschbaum,et al.  Burnout, perceived stress, and cortisol responses to awakening. , 1999, Psychosomatic medicine.

[21]  Peter Schulz,et al.  Trierer Inventar zur Erfassung von chronischem Streß (TICS): Skalenkonstruktion, teststatistische Überprüfung und Validierung der Skala Arbeitsüberlastung , 1999 .

[22]  J. Smyth,et al.  STRESSORS AND MOOD MEASURED ON A MOMENTARY BASIS ARE ASSOCIATED WITH SALIVARY CORTISOL SECRETION , 1998, Psychoneuroendocrinology.

[23]  C. Kirschbaum,et al.  Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload , 1998 .

[24]  B. McEwen.  Protective and damaging effects of stress mediators. , 1998, The New England journal of medicine.

[25]  J. Schwartz,et al.  Does the relationship of ambulatory blood pressure to position and location vary by age, sex, race/ethnicity, or body mass index? , 1998, American journal of human biology : the official journal of the Human Biology Council.

[26]  C. Kirschbaum,et al.  Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical activity. , 1997, Life sciences.

[27]  K. Pennert,et al.  Does it matter whether ambulatory blood pressure is recorded during a work day or a non-work day? , 1996, Journal of hypertension.

[28]  H. Berkhof,et al.  Individual differences in cortisol responses to a laboratory speech task and their relationship to responses to stressful daily events , 1996, Biological Psychology.

[29]  J. Smyth,et al.  Effect of Chronic Stress Associated With Unemployment on Salivary Cortisol: Overall Cortisol Levels, Diurnal Rhythm, and Acute Stress Reactivity , 1995, Psychosomatic medicine.

[30]  C. Kirschbaum,et al.  Salivary cortisol in psychoneuroendocrine research: Recent developments and applications , 1994, Psychoneuroendocrinology.

[31]  G. Davey.  Trait factors and ratings of controllability as predictors of worrying about significant life stressors , 1994 .

[32]  Joseph E. Schwartz,et al.  Mood, Location and Physical Position as Predictors of Ambulatory Blood Pressure and Heart Rate: Application of a Multi-Level Random Effects Model , 1994, Annals of Behavioral Medicine.

[33]  S. Shiffman,et al.  Ecological Momentary Assessment (Ema) in Behavioral Medicine , 1994 .

[34]  D. Hellhammer,et al.  Endocrine correlates of stress vulnerability. , 1993, Psychotherapy and psychosomatics.

[35]  C. Kirschbaum,et al.  Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement , 1992, The Journal of Steroid Biochemistry and Molecular Biology.

[36]  J. Born,et al.  Nocturnal adrenocorticotropin and cortisol secretion depends on sleep duration and decreases in association with spontaneous awakening in the morning. , 1992, The Journal of clinical endocrinology and metabolism.

[37]  D. J. Mullaney,et al.  Automatic sleep/wake identification from wrist activity. , 1992, Sleep.

[38]  P. Mansfield,et al.  Women and their husbands: mood and arousal fluctuations across the menstrual cycle and days of the week. , 1989, Psychosomatic medicine.

[39]  A. Z. Arthur.  Stress as a State of Anticipatory Vigilance , 1987, Perceptual and motor skills.

[40]  John M. Neale,et al.  Prospective and cross-sectional mood reports offer no evidence of a "blue Monday" phenomenon. , 1985 .

[41]  F. E. Grubbs.  Procedures for Detecting Outlying Observations in Samples , 1969 .