Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization
暂无分享,去创建一个
Dan M Roden | Aravinda Chakravarti | Stefan Kääb | Serena Sanna | Calum A MacRae | Arne Pfeufer | Randall T Peterson | A. Chakravarti | D. Roden | D. Arking | A. Pfeufer | A. Amsterdam | D. Rosenbaum | S. Sanna | R. Peterson | S. Kääb | C. Macrae | D. Milan | Jeffrey R Winterfield | David S Rosenbaum | David J Milan | Ian L Jones | Dan E Arking | J. Mably | John D Mably | Albert M Kim | Adam H Amsterdam | Khaled M Sabeh | J. Winterfield | A. M. Kim | Ian L. Jones | Khaled Sabeh
[1] Thomas Lumley,et al. Common variants at ten loci influence QT interval duration in the QTGEN Study , 2009, Nature Genetics.
[2] Christian Gieger,et al. Common variants at ten loci modulate the QT interval duration in the QTSCD Study , 2009, Nature Genetics.
[3] T. Zhong,et al. Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish. , 2008, Developmental biology.
[4] S. Horvath,et al. Variations in DNA elucidate molecular networks that cause disease , 2008, Nature.
[5] E. Marbán,et al. CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart , 2008, Proceedings of the National Academy of Sciences.
[6] Benjamin Meder,et al. Deficient Zebrafish Ether-à-Go-Go-Related Gene Channel Gating Causes Short-QT Syndrome in Zebrafish Reggae Mutants , 2008, Circulation.
[7] Russell A. Wilke,et al. Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges , 2007, Nature Reviews Drug Discovery.
[8] D. Levy,et al. Common Genetic Variation in KCNH2 Is Associated With QT Interval Duration: The Framingham Heart Study , 2007, Circulation.
[9] Jan Huisken,et al. Zebrafish model for human long QT syndrome , 2007, Proceedings of the National Academy of Sciences.
[10] Michael J Ackerman,et al. Mutant Caveolin-3 Induces Persistent Late Sodium Current and Is Associated With Long-QT Syndrome , 2006, Circulation.
[11] M. Fishman,et al. santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish , 2006, Development.
[12] Christian Gieger,et al. A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization , 2006, Nature Genetics.
[13] Calum A MacRae,et al. Notch1b and neuregulin are required for specification of central cardiac conduction tissue , 2006, Development.
[14] Wolfgang Rottbauer,et al. High-throughput assay for small molecules that modulate zebrafish embryonic heart rate , 2005, Nature chemical biology.
[15] J. Nerbonne,et al. Molecular physiology of cardiac repolarization. , 2005, Physiological reviews.
[16] R. Holle,et al. Common Variants in Myocardial Ion Channel Genes Modify the QT Interval in the General Population: Results From the KORA Study , 2005, Circulation research.
[17] S. Priori,et al. Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers. , 2004, JAMA.
[18] S. Priori,et al. Association of Long QT Syndrome Loci and Cardiac Events Among Patients Treated With β-Blockers , 2004 .
[19] Nancy Hopkins,et al. Identification of 315 genes essential for early zebrafish development. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[20] A. Bozio,et al. Long QT syndrome in neonates: conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations. , 2004, Journal of the American College of Cardiology.
[21] Giuseppe Curigliano,et al. Drug-induced prolongation of the QT interval. , 2004, The New England journal of medicine.
[22] I. Novak,et al. Sodium and chloride transport in soft water and hard water acclimated zebrafish (Danio rerio). , 2003, Biochimica et biophysica acta.
[23] M. Fishman,et al. heart of glass Regulates the Concentric Growth of the Heart in Zebrafish , 2003, Current Biology.
[24] Gabriele Vacun,et al. Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia. , 2003, Toxicology and applied pharmacology.
[25] J. Erdmann,et al. A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization. , 2003, Cardiovascular research.
[26] Robert P. Thompson,et al. Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus hearts. , 2003, American journal of physiology. Heart and circulatory physiology.
[27] Calum A. MacRae,et al. Drugs That Induce Repolarization Abnormalities Cause Bradycardia in Zebrafish , 2003, Circulation.
[28] A. Gramolini,et al. Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death , 2003, Nature.
[29] J. Briggs. The zebrafish: a new model organism for integrative physiology. , 2002, American journal of physiology. Regulatory, integrative and comparative physiology.
[30] M. Sanguinetti,et al. Molecular and Cellular Mechanisms of Cardiac Arrhythmias , 2001, Cell.
[31] R. Prescott,et al. The relationship between QT intervals and mortality in ambulant patients with chronic heart failure. The united kingdom heart failure evaluation and assessment of risk trial (UK-HEART) , 1999, European heart journal.
[32] C. Nüsslein-Volhard,et al. Mutations affecting the cardiovascular system and other internal organs in zebrafish. , 1996, Development.
[33] T. Raghunathan,et al. Clinically silent electrocardiographic abnormalities and risk of primary cardiac arrest among hypertensive patients. , 1996, Circulation.
[34] P. Gillette,et al. Infants with long-QT syndrome and 2:1 atrioventricular block. , 1995, American heart journal.
[35] C. Nüsslein-Volhard,et al. Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate , 1994, Current Biology.
[36] A. Garson,et al. Prolonged QT interval in hypertrophic and dilated cardiomyopathy in children. , 1994, American heart journal.
[37] G. Vincent. Hypothesis for the molecular physiology of the Romano-Ward long QT syndrome. , 1992, Journal of the American College of Cardiology.
[38] M. Dick,et al. Two:one atrioventricular block in infants with congenital long QT syndrome. , 1987, The American journal of cardiology.
[39] W. Catterall,et al. Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore. , 1978, The Journal of biological chemistry.