Study on the Process of Drafting Alkaloids Extraction from Fritillaria Cirrhosa by Supercritical CO_2 Fluid

This experiment was carried out by supercritical CO2 fluid technology to extract the drifting alkaloids from Fritillaria cirrhosa.The pressure,temperature,extract time and modifier consumption were selected as the inspection conditions in single factor experiment.And on the basis of it,orthogonal experiment was carried out.The result indicates that the pressure and temperature are the mainly influential factors for the extraction of alkaloids.Analysis of the orthogonal experiment indicates that the best conditions to extract the drifting alkaloids from fritillaria cirrhosa are A1B3C3D2,i.e.,pressure: 20MPa,Ethyl alcohol consumption: 300ml,extract time:2 hours,temperature: 45℃,and the extraction rate:0.195%.