Regulation of imaginal disc cell size, cell number and organ size by Drosophila class IA phosphoinositide 3-kinase and its adaptor

[1]  E. Hafen,et al.  Drosophila S6 kinase: a regulator of cell size. , 1999, Science.

[2]  E. Hafen,et al.  Autonomous Control of Cell and Organ Size by CHICO, a Drosophila Homolog of Vertebrate IRS1–4 , 1999, Cell.

[3]  A. Casamayor,et al.  PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2 , 1999, Current Biology.

[4]  M. Waterfield,et al.  Signalling through phosphoinositide 3-kinases: the lipids take centre stage. , 1999, Current opinion in cell biology.

[5]  Lewis C. Cantley,et al.  The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function* , 1999, The Journal of Biological Chemistry.

[6]  D. Emlen,et al.  The developmental basis for allometry in insects. , 1999, Development.

[7]  I. Conlon,et al.  Size Control in Animal Development , 1999, Cell.

[8]  P J Bryant,et al.  A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells. , 1999, Development.

[9]  L. Pirola,et al.  Structure and function of phosphoinositide 3-kinases. , 1998, Biochimica et biophysica acta.

[10]  M. Dominguez,et al.  A dorsal/ventral boundary established by Notch controls growth and polarity in the Drosophila eye , 1998, Nature.

[11]  Entwistle.  A comparison between the use of a high‐resolution CCD camera and 35 mm film for obtaining coloured micrographs , 1998, Journal of microscopy.

[12]  A. Klippel,et al.  Activation of Phosphatidylinositol 3-Kinase Is Sufficient for Cell Cycle Entry and Promotes Cellular Changes Characteristic of Oncogenic Transformation , 1998, Molecular and Cellular Biology.

[13]  J. Woodgett,et al.  Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. , 1998, The Biochemical journal.

[14]  K. Siddle,et al.  Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. , 1998, The Biochemical journal.

[15]  T. P. Neufeld,et al.  Coordination of Growth and Cell Division in the Drosophila Wing , 1998, Cell.

[16]  J. Thomas,et al.  Methuselah meets diabetes. , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.

[17]  J. Downward.  SIGNAL TRANSDUCTION: Lipid-Regulated Kinases: Some Common Themes at Last , 1998 .

[18]  G M Rubin,et al.  Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. , 1998, Development.

[19]  A. Eszterhas,et al.  TGF-beta 1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells. , 1997, The American journal of physiology.

[20]  G. Thomas,et al.  TOR signalling and control of cell growth. , 1997, Current opinion in cell biology.

[21]  A. Eszterhas,et al.  TGF-β1 modulates EGF-stimulated phosphatidylinositol 3-kinase activity in human airway smooth muscle cells. , 1997, American journal of physiology. Lung cellular and molecular physiology.

[22]  M. Heisenberg,et al.  Isolation and characterization of the droPIK57 gene encoding a new regulatory subunit of phosphatidylinositol 3-kinase from Drosophila melanogaster. , 1997, Gene.

[23]  C. Lehner,et al.  Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. , 1997, Development.

[24]  Koutarou D. Kimura,et al.  daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. , 1997, Science.

[25]  B. Zetter,et al.  Isolation of a mouse cDNA encoding mSTI1, a stress-inducible protein containing the TPR motif. , 1997, Gene.

[26]  B. Hemmings.  Update: PtdIns(3,4,5)P3 Gets Its Message Across , 1997, Science.

[27]  G. Panayotou,et al.  Phosphoinositide 3-kinases: a conserved family of signal transducers. , 1997, Trends in biochemical sciences.

[28]  M. Waterfield,et al.  p60 Is an Adaptor for the DrosophilaPhosphoinositide 3-Kinase, Dp110* , 1997, The Journal of Biological Chemistry.

[29]  A. Garcı́a-Bellido,et al.  Developmental parameters of cell death in the wing disc of Drosophila. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[30]  P. Warne,et al.  Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras , 1997, Cell.

[31]  P. O’Farrell,et al.  Limb morphogenesis: connections between patterning and growth , 1997, Current Biology.

[32]  S. Zipursky,et al.  Induction of Drosophila eye development by decapentaplegic. , 1997, Development.

[33]  E. Hafen,et al.  The Drosophila phosphoinositide 3‐kinase Dp110 promotes cell growth. , 1996, The EMBO journal.

[34]  G. Struhl,et al.  Direct and Long-Range Action of a Wingless Morphogen Gradient , 1996, Cell.

[35]  D. Rio,et al.  Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[36]  G. Ruvkun,et al.  A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans , 1996, Nature.

[37]  M. Raff,et al.  Size Control: The Regulation of Cell Numbers in Animal Development , 1996, Cell.

[38]  M. Noll,et al.  The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal , 1996, Cell.

[39]  K. Basler,et al.  Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. , 1996, Development.

[40]  J. Nevins,et al.  Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs. , 1996, Genes & development.

[41]  M. Vidal,et al.  RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila. , 1996, Genes & development.

[42]  J. Downward,et al.  Activation of phosphoinositide 3‐kinase by interaction with Ras and by point mutation. , 1996, The EMBO journal.

[43]  R. Garofalo,et al.  The Drosophila insulin receptor is required for normal growth. , 1996, Endocrinology.

[44]  M. Waterfield,et al.  A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction , 1995, Current Biology.

[45]  Michael J. Fry,et al.  Phosphatidylinositol-3-OH kinase direct target of Ras , 1994, Nature.

[46]  T. Kitamura,et al.  1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[47]  K. Hara.  Phosphoinositide 3-kinase activity is required for insulin-stimulated glucose transport but not for ras activation in CHO cells , 1994 .

[48]  P. Bryant,et al.  Tumor suppressor genes encoding proteins required for cell interactions and signal transduction in Drosophila. , 1993, Development (Cambridge, England). Supplement.

[49]  I. Kiss,et al.  P-lacW insertional mutagenesis on the second chromosome of Drosophila melanogaster: isolation of lethals with different overgrowth phenotypes. , 1993, Genetics.

[50]  T Pawson,et al.  Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach , 1993, Molecular and cellular biology.

[51]  G. Rubin,et al.  Analysis of genetic mosaics in developing and adult Drosophila tissues. , 1993, Development.

[52]  T. Pawson,et al.  SH2 domains recognize specific phosphopeptide sequences , 1993, Cell.

[53]  M. Bate,et al.  The development of Drosophila melanogaster , 1993 .

[54]  A. Bang,et al.  The Drosophila gene Hairless encodes a novel basic protein that controls alternative cell fates in adult sensory organ development. , 1992, Genes & development.

[55]  D. Maier,et al.  Hairless, a Drosophila gene involved in neural development, encodes a novel, serine rich protein , 1992, Mechanisms of Development.

[56]  D. Lindsley,et al.  The Genome of Drosophila Melanogaster , 1992 .

[57]  M. Noll,et al.  Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis. , 1987, Genes & development.

[58]  D. Ready,et al.  Neuronal differentiation in Drosophila ommatidium. , 1987, Developmental biology.

[59]  P J Bryant,et al.  Intrinsic growth control in the imaginal primordia of Drosophila, and the autonomous action of a lethal mutation causing overgrowth. , 1985, Developmental biology.

[60]  P. Bryant,et al.  Intrinsic and Extrinsic Control of Growth in Developing Organs , 1984, The Quarterly Review of Biology.

[61]  P. Simpson,et al.  The initiation of pupariation in Drosophila: dependence on growth of the imaginal discs. , 1980, Journal of embryology and experimental morphology.

[62]  J. Haynie.  The effects of X-rays on the proliferation dynamics of cells in the imaginal wing disc of Drosophila melanogaster , 1977 .

[63]  G. Morata,et al.  Minutes: mutants of drosophila autonomously affecting cell division rate. , 1975, Developmental biology.

[64]  Antonio Garcia-Bellido.  Larvalentwicklung transplantierter Organe von Drosophila melanogaster im Adultmilieu , 1965 .

[65]  J. C. Li,et al.  Development in DROSOPHILA MELANOGASTER. , 1927, Genetics.