Insulin downregulates the expression of the Ca2+-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models
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R. Vennekens | B. Nilius | K. Philippaert | T. Voets | A. Segal | F. Schuit | G. Owsianik | B. Colsoul | G. Jacobs | Griet Jacobs | Koenraad Philippaert
[1] E. Van Obberghen,et al. MicroRNAs and metabolism crosstalk in energy homeostasis. , 2013, Cell metabolism.
[2] A. Harris,et al. Transcriptional networks driving enhancer function in the CFTR gene. , 2012, The Biochemical journal.
[3] L. Marroqui,et al. REVIEW Role of leptin in the pancreatic b -cell: effects and signaling pathways , 2012 .
[4] Howard Slomko,et al. Minireview: Epigenetics of obesity and diabetes in humans. , 2012, Endocrinology.
[5] Christopher J. Ott,et al. Nucleosome occupancy reveals regulatory elements of the CFTR promoter , 2011, Nucleic acids research.
[6] P. Bougnères,et al. T2DM: Why Epigenetics? , 2011, Journal of nutrition and metabolism.
[7] J. Holst,et al. Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes. , 2011, Metabolism: clinical and experimental.
[8] R. Vennekens,et al. Transient receptor potential cation channels in pancreatic β cells. , 2011, Reviews of physiology, biochemistry and pharmacology.
[9] B. Nilius,et al. The role of transient receptor potential cation channels in Ca2+ signaling. , 2010, Cold Spring Harbor perspectives in biology.
[10] R. Penner,et al. TRPM5 regulates glucose-stimulated insulin secretion , 2010, Pflügers Archiv - European Journal of Physiology.
[11] K. Lemaire,et al. Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5−/− mice , 2010, Proceedings of the National Academy of Sciences.
[12] Bernd Nilius,et al. Transient receptor potential channelopathies , 2010, Pflügers Archiv - European Journal of Physiology.
[13] L. Groop,et al. Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes , 2009, Diabetes.
[14] D. Pipeleers,et al. Glucose, regulator of survival and phenotype of pancreatic beta cells. , 2009, Vitamins and hormones.
[15] M. Horowitz,et al. Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes , 2008, Gut.
[16] S. Arora. Leptin and its metabolic interactions – an update , 2008, Diabetes, obesity & metabolism.
[17] Per-Olof Berggren,et al. Insulin signaling in the pancreatic beta-cell. , 2008, Annual review of nutrition.
[18] P. Lindström. The Physiology of Obese-Hyperglycemic Mice [ob/ob Mice] , 2007, TheScientificWorldJournal.
[19] J. A. Peters,et al. Transient receptor potential cation channels in disease. , 2007, Physiological reviews.
[20] I. Haznedaroglu,et al. Rethinking leptin and insulin action: therapeutic opportunities for diabetes. , 2006, The international journal of biochemistry & cell biology.
[21] B. Nilius,et al. TRP channels: an overview. , 2005, Cell calcium.
[22] F. Ashcroft,et al. Type 2 diabetes mellitus: not quite exciting enough? , 2004, Human molecular genetics.
[23] J. Seufert,et al. Leptin Effects on Pancreatic β-Cell Gene Expression and Function , 2004 .
[24] D. Coleman. Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice , 1978, Diabetologia.
[25] J. Seufert. Leptin effects on pancreatic beta-cell gene expression and function. , 2004, Diabetes.
[26] R. Penner,et al. TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[27] T. Gudermann,et al. TRPM5 Is a Voltage-Modulated and Ca2+-Activated Monovalent Selective Cation Channel , 2003, Current Biology.
[28] P. Berggren,et al. Insulin feedback action on pancreatic β‐cell function , 2002 .
[29] M. Ravier,et al. Disorganization of cytoplasmic Ca2+ oscillations and pulsatile insulin secretion in islets from ob/ob mice , 2002, Diabetologia.
[30] P. Berggren,et al. Insulin feedback action on pancreatic beta-cell function. , 2002, FEBS letters.
[31] M. Ravier,et al. Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ obmice. , 2002, Diabetologia.
[32] N. Pørksen,et al. The in vivo regulation of pulsatile insulin secretion , 2002, Diabetologia.
[33] F. Speleman,et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes , 2002, Genome Biology.
[34] L. Satin,et al. Insulin activates ATP-sensitive K(+) channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway. , 2001, Diabetes.
[35] C. Kahn,et al. Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells. , 2001, Molecular cell.
[36] J. Habener,et al. Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[37] L. Tartaglia,et al. Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice , 1996, Cell.
[38] M. Pelleymounter,et al. Effects of the obese gene product on body weight regulation in ob/ob mice. , 1995, Science.
[39] A. Kuznetsov,et al. Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans. , 1994, The Journal of biological chemistry.
[40] J. Castaño. Regulation of gene expression by insulin. , 1991, Advances in enzyme regulation.
[41] S. O’Rahilly,et al. Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. , 1988, The New England journal of medicine.