Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations☆

[1]  C. la Vecchia,et al.  Clinical utility of a plasma-based miRNA signature classifier within computed tomography lung cancer screening: a correlative MILD trial study. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  Ugo Pastorino,et al.  Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial , 2012, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[3]  A. Dirksen,et al.  CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT , 2012, Thorax.

[4]  C. Croce,et al.  MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer , 2011, Proceedings of the National Academy of Sciences.

[5]  Lara J. Monteiro,et al.  Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer. , 2009, Cancer research.

[6]  F. Fazio,et al.  Fluorodeoxyglucose Uptake Measured by Positron Emission Tomography and Standardized Uptake Value Predicts Long-Term Survival of CT Screening Detected Lung Cancer in Heavy Smokers , 2009, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[7]  L. Bloom,et al.  FN3: a new protein scaffold reaches the clinic. , 2009, Drug discovery today.

[8]  Libing Song,et al.  Astrocyte elevated gene-1 is a proliferation promoter in breast cancer via suppressing transcriptional factor FOXO1 , 2009, Oncogene.

[9]  Armando Santoro,et al.  A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial. , 2009, American journal of respiratory and critical care medicine.

[10]  W. Nishio,et al.  Expression and localization of FOXO1 in non-small cell lung cancer. , 2009, Oncology reports.

[11]  J. Roman,et al.  Stimulation of lung carcinoma cell growth by fibronectin-integrin signalling. , 2008, Molecular bioSystems.

[12]  P. Bach.  Is our natural-history model of lung cancer wrong? , 2008, The Lancet. Oncology.

[13]  B. Comin-Anduix,et al.  Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma , 2008, Journal of Translational Medicine.

[14]  P. Scardino,et al.  Forkhead protein FKHR and its phosphorylated form p-FKHR in human prostate cancer. , 2007, Human pathology.

[15]  J. Lin,et al.  PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound , 2007, British Journal of Cancer.

[16]  J. Crowley,et al.  The IASLC Lung Cancer Staging Project: Proposals for the Revision of the TNM Stage Groupings in the Forthcoming (Seventh) Edition of the TNM Classification of Malignant Tumours , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[17]  O. Miettinen,et al.  Survival of patients with stage I lung cancer detected on CT screening. , 2006, The New England journal of medicine.

[18]  E. Bergstralh,et al.  Extended lung cancer incidence follow-up in the Mayo Lung Project and overdiagnosis. , 2006, Journal of the National Cancer Institute.

[19]  Takayuki Kosaka,et al.  Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[20]  J. Varakis,et al.  ILK over‐expression in human colon cancer progression correlates with activation of β‐catenin, down‐regulation of E‐cadherin and activation of the Akt–FKHR pathway , 2006, The Journal of pathology.

[21]  J. Testa,et al.  Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions. , 2004, Carcinogenesis.

[22]  U. Pastorino,et al.  Lung Cancers Detected by Screening with Spiral Computed Tomography Have a Malignant Phenotype when Analyzed by cDNA Microarray , 2004, Clinical Cancer Research.

[23]  J. Cheong,et al.  Constitutive phosphorylation of FKHR transcription factor as a prognostic variable in acute myeloid leukemia. , 2003, Leukemia research.

[24]  F. Fazio,et al.  Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2-year results , 2003, The Lancet.

[25]  Alfonso Bellacosa,et al.  AKT plays a central role in tumorigenesis , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[26]  G. Bepler,et al.  Screening for lung cancer. , 2000, The New England journal of medicine.

[27]  A. Harris,et al.  Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer , 2000, The Journal of pathology.

[28]  Kenneth M. Yamada,et al.  Fibronectin and integrins in invasion and metastasis , 1995, Cancer and Metastasis Reviews.

[29]  J. Mulshine,et al.  Early detection of lung cancer. , 1993, Seminars in oncology.

[30]  S. Horning,et al.  The natural history of initially untreated low-grade non-Hodgkin's lymphomas. , 1984, The New England journal of medicine.

[31]  B J Flehinger,et al.  Screening for early lung cancer. Results of the Memorial Sloan-Kettering study in New York. , 1984, Chest.

[32]  Andrew H. Beck,et al.  Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression , 2015, Modern Pathology.

[33]  Screening for lung cancer. Too many uncertainties, even for smokers. , 2014, Prescrire international.

[34]  C. Gatsonis,et al.  Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening , 2012 .

[35]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[36]  M. Basson.  An intracellular signal pathway that regulates cancer cell adhesion in response to extracellular forces. , 2008, Cancer research.

[37]  Douglas C McCrory,et al.  Screening for lung cancer: a review of the current literature. , 2003, Chest.

[38]  J Murtaugh,et al.  Early detection. , 1999, Journal of the American Dental Association.