论文信息 - Reduced PD-1/PD-L1 expression in KRAS-mutant versus wild-type microsatellite instable (MSI-H) colorectal cancer (CRC) and association of wnt pathway corepressor TLE-3.

Reduced PD-1/PD-L1 expression in KRAS-mutant versus wild-type microsatellite instable (MSI-H) colorectal cancer (CRC) and association of wnt pathway corepressor TLE-3.

3611 Background: MSI-H CRC comprises ~15% of CRC & has higher PD-1 & PD-L1 (P(+)) expression in CD4+ lymphocytes & tumor cells, respectively, compared to non-MSI-H CRC. Immune-checkpoint inhibitor ...

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