Special focus issue: Bioanalysis of large molecules by LC-MS.

[1]  Michael E. Lassman,et al.  Applications of low-flow LC-SRM for the analysis of large molecules in pharmaceutical R&D. , 2014, Bioanalysis.

[2]  Yan J. Zhang,et al.  The integration of ligand binding and LC-MS-based assays into bioanalytical strategies for protein analysis. , 2014, Bioanalysis.

[3]  Jean-Nicholas Mess,et al.  Application of high-resolution MS in the quantification of a therapeutic monoclonal antibody in human plasma. , 2014, Bioanalysis.

[4]  D. Dufield,et al.  Minimalistic sample preparation strategies for LC-MS quantification of large molecule biopharmaceuticals: a case study highlighting alpha-1 antitrypsin protein. , 2014, Bioanalysis.

[5]  A. Papadimitriou,et al.  Can LC-MS/MS and ligand-binding assays live in harmony for large-molecule bioanalysis? , 2014, Bioanalysis.

[6]  H. Neubert,et al.  Quantification of biotherapeutic targets: new opportunities with immunoaffinity LC-MS/MS. , 2014, Bioanalysis.

[7]  Michael E. Lassman,et al.  Development and fit-for-purpose validation of a LC-MS/MS assay for fibrinogen peptide A quantitation in human plasma. , 2014, Bioanalysis.

[8]  D. Shuster,et al.  Quantification of human mAbs in mouse tissues using generic affinity enrichment procedures and LC-MS detection. , 2014, Bioanalysis.

[9]  M. Maia,et al.  A multiplexed hybrid LC-MS/MS pharmacokinetic assay to measure two co-administered monoclonal antibodies in a clinical study. , 2014, Bioanalysis.

[10]  Hao Jiang,et al.  An exploratory universal LC-MS/MS assay for bioanalysis of hinge region-stabilized human IgG4 mAbs in clinical studies. , 2014, Bioanalysis.

[11]  F. Vazvaei,et al.  Validation of LC-MS/MS bioanalytical methods for protein therapeutics. , 2014, Bioanalysis.

[12]  Michael E. Lassman,et al.  Quantitation of human peptides and proteins via MS: review of analytically validated assays. , 2014, Bioanalysis.