Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells

[1]  D. Brat,et al.  Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival. , 2010, Cancer research.

[2]  E. Giovannucci,et al.  Coffee, Tea, Caffeine Intake, and Risk of Adult Glioma in Three Prospective Cohort Studies , 2010, Cancer Epidemiology, Biomarkers & Prevention.

[3]  Y. Bae,et al.  The p53-p21Cip1/WAF1 pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells , 2009, Molecules and cells.

[4]  J. Villano,et al.  Temozolomide in malignant gliomas: current use and future targets , 2009, Cancer Chemotherapy and Pharmacology.

[5]  Jiyoung Kim,et al.  Iron-saturated lactoferrin stimulates cell cycle progression through PI3K/Akt pathway , 2009, Molecules and cells.

[6]  K. Kawakami,et al.  Potential Therapeutic Effect of Glycogen Synthase Kinase 3β Inhibition against Human Glioblastoma , 2009, Clinical Cancer Research.

[7]  Jia Luo,et al.  Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. , 2009, Cancer letters.

[8]  Y. Murawaki,et al.  Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway. , 2008, Basic & clinical pharmacology & toxicology.

[9]  Chang Gun Kim,et al.  p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression. , 2008, Cancer research.

[10]  Y. Lou,et al.  Stimulatory effect of oral administration of tea, coffee or caffeine on UVB-induced apoptosis in the epidermis of SKH-1 mice. , 2007, Toxicology and applied pharmacology.

[11]  Mark R Gilbert,et al.  Chemoradiotherapy in malignant glioma: standard of care and future directions. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[12]  B. Gabrielli,et al.  Caffeine Promotes Apoptosis in Mitotic Spindle Checkpoint-arrested Cells* , 2007, Journal of Biological Chemistry.

[13]  A. Bode,et al.  The enigmatic effects of caffeine in cell cycle and cancer. , 2007, Cancer letters.

[14]  K. Blomgren,et al.  Pathological apoptosis in the developing brain , 2007, Apoptosis.

[15]  S. Maddika,et al.  Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy. , 2007, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[16]  M. Berens,et al.  Molecular targets of glioma invasion , 2007, Cellular and Molecular Life Sciences.

[17]  Jie Liao,et al.  Inhibition of adenoma progression to adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model in A/J mice by tea polyphenols and caffeine. , 2006, Cancer research.

[18]  H. Harn,et al.  The natural compound n-butylidenephthalide derived from Angelica sinensis inhibits malignant brain tumor growth in vitro and in vivo3 , 2006, Journal of neurochemistry.

[19]  K. Nakayama,et al.  Phosphorylation of β-Catenin by Cyclic AMP-Dependent Protein Kinase Stabilizes β-Catenin through Inhibition of Its Ubiquitination , 2005, Molecular and Cellular Biology.

[20]  Z. Dong,et al.  Inhibition of epidermal growth factor‐induced cell transformation and Akt activation by caffeine , 2005, Molecular carcinogenesis.

[21]  T. Veenstra,et al.  Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis , 2005, Clinical & Experimental Metastasis.

[22]  Kimi Yamakoshi,et al.  The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression. , 2004, The journal of medical investigation : JMI.

[23]  Weiya Ma,et al.  Caffeine inhibits cell proliferation by G0/G1 phase arrest in JB6 cells. , 2004, Cancer research.

[24]  Weiya Ma,et al.  Induction of apoptosis by caffeine is mediated by the p53, Bax, and caspase 3 pathways. , 2003, Cancer research.

[25]  B. Doble,et al.  GSK-3: tricks of the trade for a multi-tasking kinase , 2003, Journal of Cell Science.

[26]  M. Shin,et al.  Caffeine induces apoptosis in human neuroblastoma cell line SK-N-MC. , 2002, Journal of Korean medical science.

[27]  Jesse D. Martinez,et al.  Caffeine Induces TP53-Independent G1-Phase Arrest and Apoptosis in Human Lung Tumor Cells in a Dose-Dependent Manner , 2002, Radiation research.

[28]  G. Mills,et al.  Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[29]  B. Fredholm,et al.  Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. , 1999, Pharmacological reviews.

[30]  B. Fredholm,et al.  Caffeine--an atypical drug of dependence. , 1998, Drug and alcohol dependence.

[31]  宮下 勝吉.  Potential therapeutic effect of glycogen synthase kinase 3β inhibition against human glioblastoma , 2009 .

[32]  K. Nakayama,et al.  Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination. , 2005, Molecular and cellular biology.

[33]  Kimi Yamakoshi,et al.  The p 16 INK 4 aRB pathway : molecular link between cellular senescence and tumor suppression , 2004 .