Dietary sucrose is essential to the development of liver injury in the methionine-choline-deficient model of steatohepatitis[S]
暂无分享,去创建一个
Scott M Turner | H. Ogata | J. Maher | S. Turner | J. Grenert | Hisanobu Ogata | James P Grenert | Jacquelyn J Maher | Carine Beysen | Michael K Pickens | Jim S Yan | Raymond K Ng | C. Beysen | Michael K. Pickens | Jim S. Yan | Hisanobu Ogata | R. K. Ng
[1] S. Turner,et al. Measurement of TG synthesis and turnover in vivo by 2H2O incorporation into the glycerol moiety and application of MIDA. , 2003, American journal of physiology. Endocrinology and metabolism.
[2] D. Koop,et al. Steatohepatitis induced by intragastric overfeeding in mice , 2005, Hepatology.
[3] J. Girard,et al. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. , 2008, The Journal of clinical investigation.
[4] S. Wołczyński,et al. Oxidative stress markers in preovulatory follicular fluid in humans. , 1999, Molecular human reproduction.
[5] C. Barth,et al. Dietary sucrose but not starch promotes protein-induced differences in rates of VLDL secretion and plasma lipid concentrations in rats. , 1992, Journal of NutriLife.
[6] M. Hellerstein,et al. Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects. , 2000, Journal of lipid research.
[7] R. Green,et al. Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet , 2008 .
[8] H. Towle. Glucose as a regulator of eukaryotic gene transcription , 2005, Trends in Endocrinology & Metabolism.
[9] M. Hellerstein,et al. Use of mass isotopomer distributions in secreted lipids to sample lipogenic acetyl-CoA pool in vivo in humans. , 1991, The American journal of physiology.
[10] J. Repa,et al. Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. , 2006, Cell metabolism.
[11] A. Mazur,et al. Lipid Metabolism and Antioxidant Status in Sucrose vs. Potato-Fed Rats , 2008, Journal of the American College of Nutrition.
[12] M. Hellerstein,et al. Measurement of de novo hepatic lipogenesis in humans using stable isotopes. , 1991, The Journal of clinical investigation.
[13] D. Vance,et al. The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes. , 1988, The Journal of biological chemistry.
[14] D. Vance,et al. A Choline-deficient Diet in Mice Inhibits neither the CDP-choline Pathway for Phosphatidylcholine Synthesis in Hepatocytes nor Apolipoprotein B Secretion* , 2004, Journal of Biological Chemistry.
[15] S. Turner,et al. Physiologic and Pharmacologic Factors Influencing Glyceroneogenic Contribution to Triacylglyceride Glycerol Measured by Mass Isotopomer Distribution Analysis* , 2005, Journal of Biological Chemistry.
[16] G. Gores,et al. The lysosomal‐mitochondrial axis in free fatty acid–induced hepatic lipotoxicity , 2008, Hepatology.
[17] I. Leclercq,et al. Central role of PPARα‐dependent hepatic lipid turnover in dietary steatohepatitis in mice , 2003, Hepatology.
[18] M. Miyazaki,et al. Regulation of stearoyl-CoA desaturases and role in metabolism. , 2004, Progress in lipid research.
[19] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[20] Robert V Farese,et al. Triglyceride accumulation protects against fatty acid-induced lipotoxicity , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[21] G. Gores,et al. Free Fatty Acids Induce JNK-dependent Hepatocyte Lipoapoptosis* , 2006, Journal of Biological Chemistry.
[22] P. J. Jones,et al. Tracing lipogenesis in humans using deuterated water. , 1996, Canadian journal of physiology and pharmacology.
[23] D. Schoeller,et al. In vivo measurement of fatty acids and cholesterol synthesis using D2O and mass isotopomer analysis. , 1994, The American journal of physiology.
[24] S. McCall,et al. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis , 2007, Hepatology.
[25] D. Vance,et al. The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion Published, JLR Papers in Press, June 26, 2007. , 2007, Journal of Lipid Research.
[26] Robert V Farese,et al. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat , 2000, Nature Genetics.
[27] A. Astrup,et al. Ad libitum intake of low-fat diets rich in either starchy foods or sucrose: effects on blood lipids, factor VII coagulant activity, and fibrinogen. , 2000, Metabolism: clinical and experimental.
[28] R. Green,et al. The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. , 2004, Journal of hepatology.
[29] J. Schwarz,et al. Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets. , 2003, The American journal of clinical nutrition.
[30] D. Small. The effects of glyceride structure on absorption and metabolism. , 1991, Annual review of nutrition.
[31] M. Sakurai,et al. A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[32] R. E. Pitas,et al. Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1 s⃞ Published, JLR Papers in Press, July 8, 2006. , 2006, Journal of Lipid Research.
[33] R. Green,et al. Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[34] R. Krauss,et al. Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance. , 1999, The Journal of clinical investigation.
[35] J. Jessurun,et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. , 2005, The Journal of clinical investigation.
[36] D. Ginzinger. Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream. , 2002, Experimental hematology.
[37] D. Vance,et al. The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. , 2006, Cell metabolism.
[38] Dong Wang,et al. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. , 2006, American journal of physiology. Endocrinology and metabolism.
[39] I. Leclercq,et al. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. , 2000, The Journal of clinical investigation.
[40] H. Sul,et al. Dissociation between adipose tissue fluxes and lipogenic gene expression in ob/ob mice. , 2007, American journal of physiology. Endocrinology and metabolism.
[41] L. Glimcher,et al. Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1 , 2008, Science.
[42] Pascale Bossard,et al. ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver. , 2008, The Journal of clinical investigation.
[43] J. Folch,et al. A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.
[44] M. Czaja,et al. Jnk1 but not jnk2 promotes the development of steatohepatitis in mice , 2006, Hepatology.
[45] G. Gores,et al. Transcriptional Regulation of Bim by FoxO3A Mediates Hepatocyte Lipoapoptosis* , 2007, Journal of Biological Chemistry.
[46] G. Gores,et al. Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. , 2003, Journal of hepatology.
[47] Kun Wook Chung,et al. Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytess⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplementary data in the form of three figures. Published, JLR Papers in Press, October 18, 2007. , 2008, Journal of Lipid Research.
[48] M. Yeh,et al. Hepatic free fatty acids accumulate in experimental steatohepatitis: role of adaptive pathways. , 2008, Journal of hepatology.
[49] S. Kakar,et al. Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury 1 s⃞ Published, JLR Papers in Press, May 27, 2007. , 2007, Journal of Lipid Research.