Accuracy of point‐of‐care‐testing (POCT) for determining hemoglobin concentrations

Background: While point‐of‐care testing (POCT) is being used increasingly as a basis for deciding on perioperative erythrocyte transfusion, no valid standards currently exist concerning the accuracy of Hb concentration measurements. For clinical employment, however, the confidence limits (±2 SD) of these measurements should lie close to 5 g/l. The aim of the present study was to evaluate the accuracy and precision of point‐of‐care testing for blood hemoglobin concentration (cHb in g/l) measurements in critically ill patients.

[1]  W. Zijlstra,et al.  Standardization of hemoglobinometry. I. The extinction coefficient of hemiglobincyanide. , 1960, Clinica chimica acta; international journal of clinical chemistry.

[2]  Willem G. Zijlstra,et al.  Standardization of hemoglobinometry: III. Preparation and use of a stable hemiglobin-cyanide standard , 1962 .

[3]  Limits of performance for measurement of blood haemoglobin concentration, number concentration of erythrocytes, and erythrocyte volume fraction in interlaboratory trials. Results of the Finnish proficiency testing programme in haematology. , 1980, Scandinavian journal of clinical and laboratory investigation.

[4]  A. Hutchison,et al.  Too much heparin: possible source of error in blood gas analysis. , 1983, British medical journal.

[5]  D. Altman,et al.  STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT , 1986, The Lancet.

[6]  J M Bland,et al.  Statistical methods for assessing agreement between two methods of clinical measurement , 1986 .

[7]  R. Verwilghen Recommendations for reference method for haemoglobinometry in human blood (ICSH standard 1986) and specifications for international haemiglobincyanide reference preparation (3rd edition). International Committee for Standardization in Haematology; Expert Panel on Haemoglobinometry. , 1987, Clinical and laboratory haematology.

[8]  W. Zijlstra,et al.  A new trend in blood gas chemistry: the measurement of clinically relevant hemoglobin derivatives. Performance of the OSM3 hemoximeter. , 1987, Scandinavian journal of clinical and laboratory investigation. Supplementum.

[9]  D. Pohland Evaluation of the Automated Haematology Analyser Sysmex M-2000 , 1989, Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie.

[10]  [Determination of hemoglobin concentration using the hemoglobin azide method in traumatic emergencies]. , 1990, Der Anaesthesist.

[11]  D. Stevenson,et al.  Measurement of carboxyhemoglobin and total hemoglobin by five specialized spectrophotometers (CO-oximeters) in comparison with reference methods. , 1993, Clinical chemistry.

[12]  A. Gong Near-patient measurements of methemoglobin, oxygen saturation, and total hemoglobin: evaluation of a new instrument for adult and neonatal intensive care. , 1995, Critical care medicine.

[13]  A Comparison of Four Bedside Methods of Hemoglobin Assessment During Cardiac Surgery , 1995, Anesthesia and analgesia.

[14]  Andrew D. Rosenberg,et al.  Practice Guidelines for Blood Component Therapy: A Report by the American Society of Anesthesiologists Task Force on Blood Component Therapy , 1996, Anesthesiology.

[15]  P. Günter Practice guidelines for blood component therapy. , 1996, Anesthesiology.

[16]  Perioperative on-site haemoglobin determination: as accurate as laboratory values? , 1996, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[17]  P. Gunter Practice Guidelines for Blood Component Therapy , 1996 .

[18]  A J Mortimer,et al.  Evaluation of the HemoCue® for measuring intra‐operative haemoglobin concentrations: a comparison with the Coulter Max‐M® , 1998, Anaesthesia.

[19]  J D Milam,et al.  Practice parameter for the use of red blood cell transfusions: developed by the Red Blood Cell Administration Practice Guideline Development Task Force of the College of American Pathologists. , 1998, Archives of pathology & laboratory medicine.

[20]  S. Kleinman,et al.  A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care , 1999 .

[21]  G. Wells,et al.  A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. , 1999, The New England journal of medicine.

[22]  Michael H. Kanter,et al.  Transfusion medicine. First of two parts--blood transfusion. , 1999 .

[23]  B. Seifert,et al.  HemoCue®, an Accurate Bedside Method of Hemoglobin Measurement? , 1997, Journal of Clinical Monitoring.