Chemical constituents from three medicinal plants: Piper renitens, Siparuna guianensis and Alternanthera brasiliana

Chemical study of three medicinal plants: from leaves of Piper renitens (Miq.) Yunck, Piperaceae, and Siparuna guianensis Aubl., Siparunaceae, and from flowers of Alternanthera brasiliana (L.) Kuntze, Amaranthaceae, resulted in isolation of nine compounds: three steroids, β-sitosterol, stigmasterol from P. renitens and sitosterol-3-O-β-D-glucopyranoside from A. brasiliana, the diterpene kaurane ent-kauran-16α,17-diol from P. renitens, two derivatives kaempferol-methylether, kumatakenine (kaempferol-3,7-dimethylether) and kaempferol-3,7,3'-trimethylether from S. guianensis and three flavones, crysoeriol (5,7,4'-trihydroxy-3'-methoxyflavone), tricin (5,7,4'-trihydroxy-3',5'-dimethoxyflavone) and 7-O-β-D-glucopyranoside-5,4'-dihydroxy-3'-methoxyflavone from A. brasiliana. Compounds structures were determinate using 1D and 2D 1H NMR and 13C spectral data, mass and IR spectra, comparing with literature data.

[1]  Sideney Becker Onofre,et al.  AÇÃO DO EXTRATO HIDROALCOÓLICO DE Alternanthera brasiliana (L.) O. KUNT., (AMARANTHACEAE) SOBRE A ATIVIDADE DE ANTIMICROBIANOS UTILIZADOS NA TERAPÊUTICA , 2011 .

[2]  M. Coelho,et al.  Siparuna guianensis Aublet ("negramina"): a review , 2010 .

[3]  Tania M. S. Silva,et al.  ESTUDO ESPECTROSCÓPICO EM ELUCIDAÇÃO ESTRUTURAL DE FLAVONOIDES DE Solanum jabrense AGRA & NEE E S. paludosum MORIC. , 2009 .

[4]  Y. Zhang,et al.  Separation and purification of tricin from an antioxidant product derived from bamboo leaves. , 2007, Journal of agricultural and food chemistry.

[5]  M. Rover,et al.  Essential Oil of Piper renitens (Miq.) Yunck Leaves and Stems (Piperaceae) from Brazilian Amazonian Forest , 2007 .

[6]  A. Awaad,et al.  Hepatoprotective activity of Schouwia thebica webb. , 2006, Bioorganic & medicinal chemistry letters.

[7]  E. Rodrigues Plants and animals utilized as medicines in the Jaú National Park (JNP), Brazilian Amazon , 2006, Phytotherapy research : PTR.

[8]  V. Paula,et al.  Constituintes químicos de Bombacopsis glabra (Bombacaceae) , 2006 .

[9]  M. Chaves,et al.  Aristolactams from Piper marginatum Jacq (Piperaceae) , 2006 .

[10]  J. Mello,et al.  Estudo mineral das espécies vegetais Alternanthera brasiliana (L.) Kuntze e Bouchea fluminensis (Vell) Mold. , 2005 .

[11]  Hildebert Wagner,et al.  ESTUDO QUÍMICO E PERFIL CROMATOGRÁFICO DAS CASCAS DE Aspidosperma parvifolium A. DC. ("PAU- PEREIRA") , 2004 .

[12]  R. Braz-Filho,et al.  Three new natural cyclopentenedione derivatives from Piper carniconnectivum , 2004 .

[13]  Isabele R. Nascimento,et al.  Diterpene esters of aristolochic acids from Aristolochia pubescens. , 2003, Phytochemistry.

[14]  E. D. Sousa,et al.  Flavonóides glicosilados das folhas e flores de Bauhinia forficata (Leguminosae) , 2003 .

[15]  David J Newman,et al.  Natural products as sources of new drugs over the period 1981-2002. , 2003, Journal of natural products.

[16]  S. S. Costa,et al.  Flavonol robinobiosides and rutinosides from Alternanthera brasiliana (Amaranthaceae) and their effects on lymphocyte proliferation in vitro , 2003 .

[17]  N. K. Simas,et al.  Chemistry and pharmacology of Monimiaceae: a special focus on Siparuna and Mollinedia. , 1999, Journal of ethnopharmacology.

[18]  A. I. Gray,et al.  Cepharanone B from Piper tuberculatum , 1999 .

[19]  L. G. Lohmann,et al.  Flora da Reserva Ducke. Guia de identificacao das plantas vasculares de uma floresta de terra-firme na Amazonia Central , 1999 .

[20]  M. Machado,et al.  Seasonal Variation of (E)-Nerolidol in Siparuna guianensis Aublet and 13C-NMR Spectral Assignments of (E)- and (Z)-Nerolidol , 1998 .

[21]  E. Andrade,et al.  Essential Oils of Siparuna guianensis Aubl. , 1998 .

[22]  L. Lohmann,et al.  Phylogenetic Position and Floral Function of Siparuna (Siparunaceae: Laurales) , 1997, International Journal of Plant Sciences.

[23]  C. Olsen,et al.  Phytochemistry of the genus Piper , 1997 .

[24]  P. A. T. Macari,et al.  Identificação dos Triterpenos de Miconia albicans Triana Através de Análise por Microcomputador , 1990 .

[25]  K. R. Markham,et al.  Comparative flavonoid glycoside biochemistry as a chemotaxonomic tool in the subdivision of the classical ‘genus’ Lycopodium , 1980 .

[26]  J. Maia,et al.  Oxoaporphine alkaloids from Fusea longifolia and Siparuna guianensis , 1976 .