High genomic deleterious mutation rates in hominids

[1]  Kim Hill,et al.  Ache Life History: The Ecology and Demography of a Foraging People , 1995 .

[2]  P. Keightley.  Nature of deleterious mutation load in Drosophila. , 1996, Genetics.

[3]  M. Kimura,et al.  The neutral theory of molecular evolution. , 1983, Scientific American.

[4]  M. Kimura,et al.  The mutational load with epistatic gene interactions in fitness. , 1966, Genetics.

[5]  M. Kimura.  The Neutral Theory of Molecular Evolution: Introduction , 1983 .

[6]  A. Kondrashov.  Contamination of the genome by very slightly deleterious mutations: why have we not died 100 times over? , 1995, Journal of theoretical biology.

[7]  A. Bird,et al.  Number of CpG islands and genes in human and mouse. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Y. Ina.  Estimation of the Transition/Transversion Ratio , 1998, Journal of Molecular Evolution.

[9]  J. Crow,et al.  Mutations affecting fitness in Drosophila populations. , 1977, Annual review of genetics.

[10]  Nancy Howell.  Demography of the Dobe! Kung , 1979 .

[11]  J. Crow.  The high spontaneous mutation rate: is it a health risk? , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[12]  T. Ohta,et al.  Synonymous and nonsynonymous substitutions in mammalian genes and the nearly neutral theory. , 1995, Journal of molecular evolution.

[13]  R. Lande.  RISK OF POPULATION EXTINCTION FROM FIXATION OF NEW DELETERIOUS MUTATIONS , 1994, Evolution; international journal of organic evolution.

[14]  H. Muller,et al.  Our load of mutations. , 1950, American journal of human genetics.

[15]  N. M. Brooke,et al.  A molecular timescale for vertebrate evolution , 1998, Nature.

[16]  J. Thompson,et al.  The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. , 1997, Nucleic acids research.

[17]  B. Charlesworth,et al.  Genetic loads and estimates of mutation rates in highly inbred plant populations , 1990, Nature.

[18]  J. Crow,et al.  A molecular approach to estimating the human deleterious mutation rate , 1993, Human mutation.

[19]  M. Adams,et al.  How many genes in the human genome? , 1994, Nature Genetics.

[20]  D Graur,et al.  Patterns and rates of indel evolution in processed pseudogenes from humans and murids. , 1997, Gene.

[21]  M. Gouy,et al.  HOVERGEN: a database of homologous vertebrate genes. , 1994, Nucleic acids research.

[22]  Michael F. Hammer,et al.  A recent common ancestry for human Y chromosomes , 1995, Nature.

[23]  J. Neel,et al.  Search for mutations altering protein charge and/or function in children of atomic bomb survivors: final report. , 1988, American journal of human genetics.

[24]  Wen-Hsiung Li,et al.  Mutation rates differ among regions of the mammalian genome , 1989, Nature.

[25]  J. Drake,et al.  Rates of spontaneous mutation. , 1998, Genetics.

[26]  H. Mohrenweiser,et al.  Frequency of thermostability variants: estimation of total "rare" variant frequency in human populations. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[27]  N. Takahata.  Neutral theory of molecular evolution. , 1996, Current opinion in genetics & development.

[28]  C. Groves,et al.  Toward a phylogenetic classification of Primates based on DNA evidence complemented by fossil evidence. , 1998, Molecular phylogenetics and evolution.