Pulmonary aspergilloma: surgical outcome of 79 patients in a Moroccan center

Background Pulmonary aspergilloma presents in two clinical and radiological forms: simple and complex aspergilloma. Surgery is the best therapeutic option, most often by anatomic lung resection. Our aim was to report the surgical outcomes according to our experience. Methods A retrospective study was conducted on data of 79 patients operated on for pulmonary aspergilloma over a period of 10 years. There were 57 (72.15%) men and 22 women (27.84%), with a mean age of 40.45 years. Results Tuberculosis, all-form combined, was the predominant pathological antecedent in 57 (72.15%) patients, and hemoptysis was the most frequent functional sign in 43 (54.43%). The right side was involved in 39 (49.36%) patients. All patients were operated on via a posterolateral thoracotomy, and an extrapleural plane was necessary in 40 (50.63%). The surgical procedure was a lobectomy in 38 (48.10%) patients and a pneumonectomy in 14 (17.72%). Transfusion of red blood cells was carried out in 10 (12.65%) patients, with one (1.26%) requiring a rethoracotomy for postoperative clotted hemothorax. Two (2.53%) patients presented with empyema after pneumonectomy. The mortality rate was 2.53% (2 patients), and the mean follow-up was 2.5 years. Conclusion Surgery for pulmonary aspergilloma is associated with a high rate of morbidity and mortality. This surgery has been performed in our department with a very acceptable rate of mortality, especially considering that all patients were operated on by open surgery.

[1]  M. Boudaya,et al.  [Surgery for thoracic tuberculosis]. , 2015, Revue de pneumologie clinique.

[2]  T. Kilani,et al.  [Conservative surgery in pulmonary aspergilloma]. , 2012, Revue des maladies respiratoires.

[3]  A. Brik,et al.  Surgical outcome of pulmonary aspergilloma. , 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[4]  A. Benosman,et al.  Chirurgie des aspergillomes pulmonaires , 2006 .

[5]  A. Benosman,et al.  [Surgical treatment of pulmonary aspergilloma. 278 cases]. , 2006, Presse medicale.

[6]  F. Gharagozloo,et al.  Postpneumonectomy and postlobectomy empyema. , 2006, Thoracic surgery clinics.

[7]  A. Bernard,et al.  Empyema and bronchopleural fistula after pneumonectomy: factors affecting incidence. , 2001, The Annals of thoracic surgery.

[8]  S. Kohno,et al.  Clinical evaluation of 61 patients with pulmonary aspergilloma. , 2000, Internal medicine.

[9]  J. Régnard,et al.  Aspergilloma: a series of 89 surgical cases. , 2000, The Annals of thoracic surgery.

[10]  P. Kay,et al.  Surgical management of pulmonary aspergilloma. , 1997, Thorax.

[11]  J. Wain Management of late postpneumonectomy empyema and bronchopleural fistula. , 1996, Chest surgery clinics of North America.

[12]  V. Young,et al.  Operation for cavitating invasive pulmonary aspergillosis in immunocompromised patients. , 1992, The Annals of thoracic surgery.

[13]  N. Amosov,et al.  Pulmonary resection with mechanical suture. , 1961, The Journal of thoracic and cardiovascular surgery.

[14]  J. Belcher,et al.  Surgery in broncho-pulmonary aspergillosis. , 1960 .

[15]  R. Sweet Closure of the bronchial stump following lobectomy or pneumonectomy , 1945 .

[16]  Chang Chen,et al.  Video-assisted thoracic surgery for pulmonary aspergilloma: a safe and effective procedure. , 2014, The Annals of thoracic surgery.

[17]  P. Sidhu,et al.  Bronchopleural fistula after pneumonectomy , 2003, Irish journal of medical science.