Soft tissue sarcomas of the extremities: Their natural history, treatment, and radiation sensitivity

The authors have attempted to explore the factors that influence the clinical course of a patient with a soft tissue tumor of the extremity (local recurrence, distant metastasis, and survival) by reviewing the literature as well as the cases at their institution. Do histology, site (proximal extremity versus distal extremity), age, or treatment significantly influence the natural history of the disease?

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