Clinical prospects of long noncoding RNAs as novel biomarkers and therapeutic targets in prostate cancer

[1]  K. Takayama,et al.  Long non‐coding RNAs and prostate cancer , 2017, Cancer science.

[2]  J. Rinn,et al.  CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo , 2015, Nature Methods.

[3]  C. Collins,et al.  The long non-coding RNA PCGEM1 is regulated by androgen receptor activity in vivo , 2015, Molecular Cancer.

[4]  S. Dhanasekaran,et al.  The landscape of long noncoding RNAs in the human transcriptome , 2015, Nature Genetics.

[5]  Yair Lotan,et al.  Can urinary PCA3 supplement PSA in the early detection of prostate cancer? , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[6]  S. Srivastava,et al.  A long noncoding RNA connects c-Myc to tumor metabolism , 2014, Proceedings of the National Academy of Sciences.

[7]  John T. Wei,et al.  RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1. , 2014, The Lancet. Oncology.

[8]  Fangting Wu,et al.  Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines , 2014, Nucleic acids research.

[9]  M. Aftab,et al.  Long noncoding RNAs as putative biomarkers for prostate cancer detection. , 2014, The Journal of molecular diagnostics : JMD.

[10]  J. Hou,et al.  Development and prospective multicenter evaluation of the long noncoding RNA MALAT-1 as a diagnostic urinary biomarker for prostate cancer , 2014, Oncotarget.

[11]  Zeping Han,et al.  Reciprocal regulation of PCGEM1 and miR-145 promote proliferation of LNCaP prostate cancer cells , 2014, Journal of experimental & clinical cancer research : CR.

[12]  J. Schalken,et al.  Noncoding RNAs as Novel Biomarkers in Prostate Cancer , 2014, BioMed research international.

[13]  S. Klauck,et al.  Novel RNA Markers in Prostate Cancer: Functional Considerations and Clinical Translation , 2014, BioMed research international.

[14]  F. Montorsi,et al.  Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer , 2014, Oncogene.

[15]  E. Pennisi.  Cell biology. Lengthy RNAs earn respect as cellular players. , 2014, Science.

[16]  D. Chan,et al.  Biomarkers in prostate cancer: what's new? , 2014, Current opinion in oncology.

[17]  S. Chanock,et al.  A comprehensive resequence‐analysis of 250 kb region of 8q24.21 in men of African ancestry , 2014, The Prostate.

[18]  Xianlin Han,et al.  The Functional Characterization of Long Noncoding RNA SPRY4-IT1 in Human Melanoma Cells , 2014, Oncotarget.

[19]  Francesca Demichelis,et al.  PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. , 2014, Cancer research.

[20]  S. Tomlins.  Urine PCA3 and TMPRSS2:ERG using cancer-specific markers to detect cancer. , 2014, European urology.

[21]  A. Chinnaiyan,et al.  The lncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer , 2014, Oncotarget.

[22]  E. Crawford,et al.  New biomarkers in prostate cancer. , 2014, Oncology.

[23]  W. Lam,et al.  Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer , 2014, Oncotarget.

[24]  J. Hou,et al.  Long noncoding RNA MALAT-1 is a new potential therapeutic target for castration resistant prostate cancer. , 2013, The Journal of urology.

[25]  B. Al-Lazikani,et al.  Drugging cancer genomes , 2013, Nature Reviews Drug Discovery.

[26]  Anna L. Walsh,et al.  Noncoding RNAs in Prostate Cancer: The Long and the Short of It , 2013, Clinical Cancer Research.

[27]  Marc S. Williams,et al.  Recommendations from the EGAPP Working Group: does PCA3 testing for the diagnosis and management of prostate cancer improve patient health outcomes? , 2013, Genetics in Medicine.

[28]  S. Dhanasekaran,et al.  The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex , 2013, Nature Genetics.

[29]  G. Deng,et al.  Noncoding RNA in Oncogenesis: A New Era of Identifying Key Players , 2013, International journal of molecular sciences.

[30]  M. Rosenfeld,et al.  LncRNA-Dependent Mechanisms of Androgen Receptor-regulated Gene Activation Programs , 2013, Nature.

[31]  Yangchao Chen,et al.  Targeting long non-coding RNAs in cancers: progress and prospects. , 2013, The international journal of biochemistry & cell biology.

[32]  L. Klotz,et al.  Prostate cancer overdiagnosis and overtreatment , 2013, Current opinion in endocrinology, diabetes, and obesity.

[33]  J. Mattick,et al.  Long noncoding RNAs and the genetics of cancer , 2013, British Journal of Cancer.

[34]  M. Rubin,et al.  Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity. , 2013, European urology.

[35]  Xiang Du,et al.  The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine , 2013, Modern Pathology.

[36]  Rong Yin,et al.  Long noncoding RNA: an emerging paradigm of cancer research , 2013, Tumor Biology.

[37]  M. Rubin,et al.  New Strategies in Prostate Cancer: Translating Genomics into the Clinic , 2012, Clinical Cancer Research.

[38]  Nadav S. Bar,et al.  Landscape of transcription in human cells , 2012, Nature.

[39]  J. Mattick,et al.  Genome-wide analysis of long noncoding RNA stability , 2012, Genome research.

[40]  A. Chinnaiyan,et al.  The emergence of lncRNAs in cancer biology. , 2011, Cancer discovery.

[41]  John T. Wei,et al.  Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression , 2011, Nature Biotechnology.

[42]  M. Kitagawa,et al.  Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene , 2011, Oncogene.

[43]  S. Srivastava,et al.  Prostate cancer: Diagnostic performance of the PCA3 urine test , 2011, Nature Reviews Urology.

[44]  Yusuke Nakamura,et al.  Association of a novel long non‐coding RNA in 8q24 with prostate cancer susceptibility , 2011, Cancer science.

[45]  B. Blencowe,et al.  The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. , 2010, Molecular cell.

[46]  P. Pandolfi,et al.  A coding-independent function of gene and pseudogene mRNAs regulates tumour biology , 2010, Nature.

[47]  A. Ruffion,et al.  Urinary prostate cancer 3 test: toward the age of reason? , 2010, Urology.

[48]  J. Schalken,et al.  The use of PCA3 in the diagnosis of prostate cancer , 2009, Nature Reviews Urology.

[49]  Wei Zhang,et al.  Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients , 2004, Oncogene.

[50]  Lin Yang,et al.  Long noncoding RNAs: fresh perspectives into the RNA world. , 2014, Trends in biochemical sciences.

[51]  R. Verhaak,et al.  Integrative genomic analyses reveal clinically relevant long non-coding RNA in human cancer , 2013 .

[52]  M. Provenzano.  [New biomarkers in prostate cancer]. , 2012, Praxis.

[53]  International Human Genome Sequencing Consortium.  Initial sequencing and analysis of the human genome , 2001, Nature.