Etiology of insulin resistance.
暂无分享,去创建一个
[1] J. Bottomley,et al. Economic costs of diabetes in the US in 2007 — Implications for Europe , 2008 .
[2] K. Petersen,et al. Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. , 2005, The Journal of clinical investigation.
[3] L. E. Hammond,et al. Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice. , 2005, Cell metabolism.
[4] K. Petersen,et al. Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. , 2005, Diabetes.
[5] Dan R. Littman,et al. PKC-θ knockout mice are protected from fat-induced insulin resistance , 2004 .
[6] P. Saha,et al. Metabolic Adaptations in the Absence of Perilipin , 2004, Journal of Biological Chemistry.
[7] P. Cavanagh,et al. Foot problems in diabetes: an overview. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[8] D. Befroy,et al. Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease* , 2004, Journal of Biological Chemistry.
[9] D. Williamson,et al. Primary Prevention of Type 2 Diabetes Mellitus by Lifestyle Intervention: Implications for Health Policy , 2004, Annals of Internal Medicine.
[10] K. Petersen,et al. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. , 2004, The New England journal of medicine.
[11] Douglas L. Rothman,et al. Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance , 2003, Science.
[12] P. Hogan,et al. Economic Costs of Diabetes in the U.S. in 2002 , 2003, Diabetes care.
[13] R. Parker,et al. Insulin resistance is a poor predictor of type 2 diabetes in individuals with no family history of disease , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[14] K. Petersen,et al. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. , 2002, The Journal of clinical investigation.
[15] Vincent Lebon,et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. , 2002, Diabetes.
[16] C. Deng,et al. Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[17] G. Shulman,et al. Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in Vivo * , 2000, The Journal of Biological Chemistry.
[18] K. Petersen,et al. Mechanism of troglitazone action in type 2 diabetes. , 2000, Diabetes.
[19] G. Shulman,et al. Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice* , 2000, The Journal of Biological Chemistry.
[20] G. Shulman,et al. On Diabetes: Insulin Resistance Cellular Mechanisms of Insulin Resistance , 2022 .
[21] R. Hammer,et al. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy , 1999, Nature.
[22] P. Scifo,et al. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. , 1999, Diabetes.
[23] Z Trajanoski,et al. Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. , 1999, The New England journal of medicine.
[24] G. Shulman,et al. Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. , 1999, Diabetes.
[25] F. Collins,et al. Familiality of Quantitative Metabolic Traits in Finnish Families with Non-Insulin-Dependent Diabetes mellitus , 1999, Human Heredity.
[26] K. Liang,et al. Body weight patterns from 20 to 49 years of age and subsequent risk for diabetes mellitus: the Johns Hopkins Precursors Study. , 1999, Archives of internal medicine.
[27] F. Schick,et al. Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. , 1999, American journal of physiology. Endocrinology and metabolism.
[28] D L Rothman,et al. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. , 1999, The Journal of clinical investigation.
[29] M. Olive,et al. Life without white fat: a transgenic mouse. , 1998, Genes & development.
[30] M. Slovenkai. Foot problems in diabetes. , 1998, The Medical clinics of North America.
[31] T. Buchanan,et al. Metabolic Effects of Troglitazone Monotherapy in Type 2 Diabetes Mellitus , 1998, Annals of Internal Medicine.
[32] B. Fielding,et al. Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects. , 1996, Metabolism: clinical and experimental.
[33] K. Petersen,et al. Mechanism of free fatty acid-induced insulin resistance in humans. , 1996, The Journal of clinical investigation.
[34] A. Kimmel,et al. Perilipin: possible roles in structure and metabolism of intracellular neutral lipids in adipocytes and steroidogenic cells. , 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.
[35] L. Rossetti,et al. Mechanisms of fatty acid-induced inhibition of glucose uptake. , 1994, The Journal of clinical investigation.
[36] T. Okada,et al. Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. , 1994, The Journal of biological chemistry.
[37] I. Godsland,et al. Role of glucose and insulin resistance in development of type 2 diabetes mellitus , 1992, The Lancet.
[38] R. N. Bergman,et al. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study , 1992, The Lancet.
[39] R. Shulman,et al. Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. , 1992, The Journal of clinical investigation.
[40] R. Shulman,et al. 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus. , 1992, The Journal of clinical investigation.
[41] A. Krolewski,et al. Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents. , 1990, Annals of internal medicine.
[42] L. Rossetti,et al. Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats. , 1990, The Journal of clinical investigation.
[43] R G Shulman,et al. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. , 1990, The New England journal of medicine.
[44] Yii-Der I. Chen,et al. Measurement of Plasma Glucose, Free Fatty Acid, Lactate, and Insulin for 24 h in Patients With NIDDM , 1988, Diabetes.
[45] P. J. Randle,et al. THE GLUCOSE FATTY ACID CYCLE IN OBESITY AND MATURITY ONSET DIABETES MELLITUS , 1965, Annals of the New York Academy of Sciences.
[46] G. Shulman,et al. PKC-theta knockout mice are protected from fat-induced insulin resistance. , 2004, The Journal of clinical investigation.
[47] A. Barcelo,et al. The cost of diabetes in Latin America and the Caribbean. , 2003, Bulletin of the World Health Organization.
[48] M. Massi-Benedetti,et al. The Costs of Type 2 Diabetes Mellitus in Italy , 2003, Treatments in endocrinology.
[49] Economic Costs of Diabetes in the U . S . in 2002 , 2003 .
[50] K. Petersen,et al. Nuclear magnetic resonance studies of hepatic glucose metabolism in humans. , 2001, Recent progress in hormone research.
[51] L. DiPietro,et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study , 1999, Diabetologia.
[52] G. Shulman,et al. Metabolic defects in lean nondiabetic offspring of NIDDM parents: a cross-sectional study. , 1997, Diabetes.
[53] W. Wahli,et al. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. , 1996, Endocrinology.