Background/Aims The HMO Research Network (HMORN) is at the forefront of the development and operation of distributed research networks for secondary use of routinely collected health information. PopMedNetTM is a distributed querying platform developed by HMORN investigators to meet HMORN and other large-scale distributed networks needs. PopMedNet is serving as the distributed querying platform for several large multi-site projects, including the FDA Mini-Sentinel and the Scalable PArtnering Network for CER: Across Lifespan, Conditions, and Settings. The substantial overhead costs associated with use of PopMedNet for HMORN activities would be best shared across projects. The ability to share secure infrastructure while maintaining compliance with national security and privacy standards such as those embodied in the Federal Information Security Management Act and those required by HMORN health plans was uncertain. Objectives Investigate the viability for creating HMORNnet, a secure architecture for implementing a single shared distributed querying infrastructure based on the PopMedNet platform that meets the privacy, proprietary, security, and research integrity demands of HMORN projects. Methods A three stage evaluation approach was undertaken in which business requirements were specified that would allow multiple HMORN projects to share a single secure hosting environment, software architecture was developed to meet the business requirements, and an investigation was conducted to determine if the approach meets security requirements. Results The business requirements specified a shared hosting environment that would: meet federal security standards, allow networks to implement their own governance policies, allow cross-network meta-data searches and activity audits, permit a single sign-on capability to facilitate multiple network activity, and allow sharing of hosting costs across projects. The architecture meets all the specified business requirements while maintaining the required security profile. Discussion A single shared secure distributed querying architecture - HMORNnet - is viable using the PopMedNet software platform. We propose the implementation of HMORNnet as a solution to maintain HMORN’s position as the leading example for a distributed research network.